Q4 2025 Holdings
Filed 2026-02-17 | 69 holdings | $1.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $159.3M | 2,000,000 | 9.6% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $110.5M | 375,000 | 6.7% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $108.0M | 3,125,000 | 6.5% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $80.2M | 3,208,875 | 4.8% |
| Revolution Medicines Inc(RVMD)Call | COM | 76155X100 | $79.7M | 1,000,000 | 4.8% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $68.5M | 310,000 | 4.1% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $53.9M | 400,000 | 3.3% |
| Erasca Inc(ERAS) | COM | 29479A108 | $48.4M | 13,000,000 | 2.9% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $42.5M | 3,500,000 | 2.6% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $41.7M | 600,000 | 2.5% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $40.5M | 510,000 | 2.4% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $39.4M | 950,000 | 2.4% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $37.2M | 4,200,000 | 2.2% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $36.1M | 500,000 | 2.2% |
| Biogen Inc(BIIB) | COM | 09062X103 | $35.2M | 200,000 | 2.1% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $35.0M | 1,375,000 | 2.1% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $34.0M | 200,000 | 2.1% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $30.3M | 750,000 | 1.8% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $30.0M | 650,000 | 1.8% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $29.5M | 850,000 | 1.8% |
| LB Pharmaceuticals Inc(LBRX) | COM SHS | 50180M108 | $26.7M | 1,200,000 | 1.6% |
| Apellis Pharmaceuticals Inc(APLS)Call | COM | 03753U106 | $25.1M | 1,000,000 | 1.5% |
| Arcus Biosciences Inc(RCUS)Call | COM | 03969F109 | $25.0M | 1,050,000 | 1.5% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $24.5M | 1,250,000 | 1.5% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $23.5M | 2,500,000 | 1.4% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $23.1M | 1,750,000 | 1.4% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $22.7M | 850,000 | 1.4% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $20.3M | 190,000 | 1.2% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $19.4M | 1,550,000 | 1.2% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $19.1M | 300,000 | 1.2% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $17.8M | 225,000 | 1.1% |
| Uniqure NV(QURE) | SHS | N90064101 | $16.2M | 675,000 | 1.0% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $15.8M | 450,000 | 1.0% |
| Ideaya Biosciences Inc(IDYA)Call | COM | 45166A102 | $15.6M | 450,000 | 0.9% |
| Kiniksa Pharmaceuticals Intl(KNSA) | ORD SHS CL A | G52694109 | $14.4M | 350,000 | 0.9% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $13.9M | 300,000 | 0.8% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $13.8M | 1,000,000 | 0.8% |
| Minerva Neurosciences Inc(NERV) | COM NEW | 603380205 | $13.3M | 3,311,000 | 0.8% |
| Verastem Inc(VSTM) | COM NEW | 92337C203 | $13.1M | 1,700,000 | 0.8% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $13.0M | 315,000 | 0.8% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $11.5M | 950,000 | 0.7% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $10.1M | 130,000 | 0.6% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $9.5M | 350,000 | 0.6% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $9.5M | 500,000 | 0.6% |
| Immatics N.v(IMTX)Call | SHS | N44445109 | $8.9M | 850,000 | 0.5% |
| CG Oncology Inc(CGON) | COM | 156944100 | $8.3M | 200,000 | 0.5% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $7.5M | 115,000 | 0.5% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $7.1M | 600,000 | 0.4% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $6.2M | 1,150,000 | 0.4% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $6.1M | 395,000 | 0.4% |