Q3 2025 Holdings
Filed 2025-11-14 | 40 holdings | $610.9M | 13F-HR | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Madrigal Pharmaceuticals Inc(MDGL) | Common | 558868105 | $46.1M | 100,415 | 7.5% |
| Cullinan Therapeutics, Inc.(CGEM) | Common | 230031106 | $45.4M | 7,648,268 | 7.4% |
| Avidity Biosciences Inc(RNA) | Common | 05370A108 | $33.1M | 760,022 | 5.4% |
| Trevi Therapeutics Inc(TRVI) | Common | 89532M101 | $31.2M | 3,406,955 | 5.1% |
| Edgewise Therapeutics Inc(EWTX) | Common | 28036F105 | $27.9M | 1,720,741 | 4.6% |
| PTC Therapeutics Inc(PTCT) | Common | 69366J200 | $26.9M | 438,477 | 4.4% |
| Zai Lab Ltd(ZLAB) | ADR | 98887Q104 | $25.3M | 745,060 | 4.1% |
| Syndax Pharmaceuticals Inc(SNDX) | Common | 87164F105 | $21.2M | 1,375,674 | 3.5% |
| Oric Pharmaceuticals Inc(ORIC) | Common | 68622P109 | $20.8M | 1,729,378 | 3.4% |
| Tarsus Pharmaceuticals Inc(TARS) | Common | 87650L103 | $20.3M | 341,496 | 3.3% |
| Xenon Pharmaceuticals Inc(XENE) | Common | 98420N105 | $20.2M | 503,398 | 3.3% |
| Stoke Therapeutics Inc(STOK) | Common | 86150R107 | $18.6M | 789,698 | 3.0% |
| Dyne Therapeutics, Inc.(DYN) | Common | 26818M108 | $18.3M | 1,446,361 | 3.0% |
| Compass Therapeutics, Inc.(CMPX) | Common | 20454B104 | $17.8M | 5,075,970 | 2.9% |
| Alkermes Plc(ALKS) | Common | G01767105 | $16.5M | 549,262 | 2.7% |
| Vera Therapeutics Inc.(VERA) | Class A Ord | 92337R101 | $16.4M | 563,075 | 2.7% |
| Natera Inc(NTRA) | Common | 632307104 | $15.9M | 98,924 | 2.6% |
| Janux Therapeutics Inc(JANX) | Common | 47103J105 | $15.0M | 614,282 | 2.5% |
| Revolution Medicines, Inc.(RVMD) | Common | 76155X100 | $14.7M | 315,722 | 2.4% |
| Context Therapeutics Inc(CNTX) | Common | 21077P108 | $14.2M | 14,705,882 | 2.3% |
| Sarepta Therapeutics Inc(SRPT) | Common | 803607100 | $13.5M | 700,000 | 2.2% |
| ARS Pharmaceuticals Inc(SPRY) | Common | 82835W108 | $13.1M | 1,303,399 | 2.1% |
| Rocket Pharmaceuticals, Inc.(RCKT) | Common | 77313F106 | $12.7M | 3,903,381 | 2.1% |
| Relay Therapeutics Inc.(RLAY) | Common | 75943R102 | $11.9M | 2,282,680 | 2.0% |
| Ultragenyx Pharmaceutical Inc(RARE) | Common | 90400D108 | $11.9M | 395,700 | 1.9% |
| Wave Life Sciences PTE LTD(WVE) | Common | Y95308105 | $11.0M | 1,505,262 | 1.8% |
| DBV Technologies S A(DBVT) | SPONSORED ADS | 23306J309 | $10.5M | 1,054,504 | 1.7% |
| Soleno Therapeutics Inc(SLNO) | Common | 834203309 | $10.1M | 150,000 | 1.7% |
| Solid Biosciences Inc(SLDB) | Common | 83422E204 | $10.1M | 1,634,569 | 1.7% |
| Akebia Therapeutics Inc(AKBA) | Common | 00972D105 | $7.9M | 2,889,125 | 1.3% |
| Werewolf Therapeutics, Inc.(HOWL) | Common | 95075A107 | $4.7M | 2,408,810 | 0.8% |
| Liquidia Corp(LQDA) | Common | 53635D202 | $4.5M | 200,000 | 0.7% |
| Palvella Therapeutics Inc(PVLA) | Common | 697947109 | $4.2M | 67,423 | 0.7% |
| Design Therapeutics Inc(DSGN) | Common | 25056L103 | $4.2M | 555,187 | 0.7% |
| Cartesian Therapeutics Inc(RNAC) | Common | 816212302 | $3.9M | 380,000 | 0.6% |
| enGene Holdings Inc(ENGN) | Common | 29286M105 | $3.6M | 530,299 | 0.6% |
| Urogen Pharma Ltd(URGN) | Common | M96088105 | $2.7M | 135,000 | 0.4% |
| Rapport Therapeutics Inc(RAPP) | Common | 75383L102 | $2.1M | 71,807 | 0.3% |
| Repare Therapeutics, Inc.(RPTX) | Common | 760273102 | $1.4M | 819,924 | 0.2% |
| Assembly Biosciences Inc(ASMB) | Common | 045396207 | $1.0M | 39,665 | 0.2% |