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Palo Alto Investors LP

Q4 2024 Holdings

Filed 2025-02-14 | 43 holdings | $645.4M | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↓Shares% Portfolio
Insmed Inc(INSM)COM PAR $.01457669307$110.7M1,603,46517.2%
Amicus Therapeutics Inc(FOLD)COM03152W109$72.2M7,662,47911.2%
Biomarin Pharmaceutical Inc(BMRN)COM09061G101$70.2M1,067,26610.9%
United Therapeutics Corp(UTHR)COM91307C102$54.9M155,7148.5%
Acadia Pharmaceuticals Inc(ACAD)COM004225108$50.4M2,748,5997.8%
Alnylam Pharmaceuticals Inc(ALNY)COM02043Q107$33.1M140,6815.1%
Biogen Inc(BIIB)COM09062X103$29.1M190,1484.5%
Sarepta Therapeutics Inc(SRPT)COM803607100$25.6M210,2584.0%
Novocure LTD(NVCR)ORD SHSG6674U108$24.3M814,1913.8%
Prothena Corp PLC(PRTA)SHSG72800108$24.1M1,737,9643.7%
Iovance Biotherapeutics Inc(IOVA)COM462260100$22.5M3,041,6853.5%
Ehealth Inc(EHTH)COM28238P109$17.7M1,878,1272.7%
PTC Therapeutics Inc(PTCT)COM69366J200$17.4M386,4132.7%
Staar Surgical Co(STAA)COM PAR $0.01852312305$12.2M500,7751.9%
Anaptysbio Inc(ANAB)COM032724106$11.2M843,9711.7%
Alkermes PLC(ALKS)SHSG01767105$8.3M289,3081.3%
Align Technology Inc(ALGN)COM016255101$7.9M37,7721.2%
Gossamer BIO Inc(GOSS)COM38341P102$5.7M6,277,0930.9%
Acelyrin IncCOM00445A100$5.6M1,792,8950.9%
Syndax Pharmaceuticals Inc(SNDX)COM87164F105$5.4M405,1930.8%
Bicycle Therapeutics PLC(BCYC)SPONSORED ADS088786108$3.5M248,9340.5%
Karyopharm Therapeutics Inc(KPTIEUR)COM48576U106$3.3M4,907,0010.5%
Verve Therapeutics IncCOM92539P101$3.2M575,8170.5%
Edwards Lifesciences Corp(EW)COM28176E108$2.9M39,4730.5%
Biontech SE(BNTX)SPONSORED ADS09075V102$2.9M25,2060.4%
Nevro Corp(NVROEUR)COM64157F103$2.8M750,3710.4%
Mirum Pharmaceuticals Inc(MIRM)COM604749101$2.7M64,7000.4%
Nuvation BIO Inc(NUVB)COM CL A67080N101$2.1M772,6520.3%
Travere Therapeutics Inc(TVTX)COM89422G107$1.9M110,7190.3%
Pyxis Oncology Inc(PYXS)COMMON STOCK747324101$1.6M1,037,4210.3%
Vyne Therapeutics Inc Pipe(VYNE)COM92941V308$1.5M445,4340.2%
Aclaris Therapeutics Inc(ACRS)COM00461U105$1.4M569,8320.2%
Taysha Gene Therapies Inc(TSHA)COM SHS877619106$1.4M811,2680.2%
Stoke Therapeutics Inc(STOK)COM86150R107$1.4M125,8610.2%
Aldeyra Therapeutics Inc(ALDX)COM01438T106$1.1M225,4650.2%
Humana Inc(HUM)COM444859102$1.0M3,9850.2%
Jasper Therapeutics Inc(JSPR)COM NEW471871202$655.3K30,6510.1%
Abeona Therapeutics Inc(ABEO)COM NEW00289Y206$606.4K108,8650.1%
Urogen Pharma LTD(URGN)COMM96088105$260.9K24,5000.0%
Relmada Therapeutics Inc(RLMD)COM75955J402$257.5K495,1460.0%
Instil BIO Inc(TIL)COM NEW45783C200$213.1K11,1650.0%
Akari Therapeutics PLC(AKTX)SPONSORED ADR00972G207$178.1K146,0240.0%
Generation BIO Co(GBIOGBX)COM37148K100$159.5K150,4750.0%