Q2 2025 Holdings
Filed 2025-08-14 | 45 holdings | $470.0M | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Insmed Inc(INSM) | COM | 457669307 | $87.1M | 865,113 | 18.5% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $55.3M | 2,563,209 | 11.8% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $46.2M | 840,470 | 9.8% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $32.1M | 5,610,513 | 6.8% |
| United Therapeutics Corp(UTHR) | COM | 91307C102 | $27.4M | 95,482 | 5.8% |
| Biogen Inc(BIIB) | SPONSORED ADS | 09062X103 | $25.8M | 205,759 | 5.5% |
| Alnylam Pharmaceuticals Inc(ALNY) | SHS | 02043Q107 | $24.6M | 75,535 | 5.2% |
| PTC Therapeutics Inc(PTCT) | SHS | 69366J200 | $19.9M | 406,469 | 4.2% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $18.0M | 812,821 | 3.8% |
| Novocure LTD(NVCR) | COM | G6674U108 | $17.1M | 962,396 | 3.6% |
| Staar Surgical Co(STAA) | COM | 852312305 | $13.3M | 791,879 | 2.8% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $8.9M | 268,783 | 1.9% |
| Prothena Corp PLC(PRTA) | COM CL A | G72800108 | $7.7M | 1,274,753 | 1.6% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $7.7M | 145,691 | 1.6% |
| Align Technology Inc(ALGN) | COM | 016255101 | $7.2M | 37,772 | 1.5% |
| Gossamer BIO Inc(GOSS) | COM | 38341P102 | $7.1M | 5,739,013 | 1.5% |
| Ehealth Inc(EHTH) | COM | 28238P109 | $6.9M | 1,577,850 | 1.5% |
| Alkermes PLC(ALKS) | COM | G01767105 | $6.3M | 221,021 | 1.3% |
| Iovance Biotherapeutics Inc(IOVA) | COM NEW | 462260100 | $5.9M | 3,429,329 | 1.3% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $4.2M | 444,367 | 0.9% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $3.4M | 118,886 | 0.7% |
| Denali Therapeutics Inc(DNLI) | COM | 24823R105 | $3.4M | 239,809 | 0.7% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $3.3M | 64,700 | 0.7% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $3.1M | 39,473 | 0.7% |
| Taysha Gene Therapies Inc(TSHA) | COM | 877619106 | $2.9M | 1,246,033 | 0.6% |
| Biontech SE(BNTX) | COM | 09075V102 | $2.7M | 25,206 | 0.6% |
| Dyne Therapeutics Inc(DYN) | SPONSORED ADS | 26818M108 | $2.5M | 264,976 | 0.5% |
| Crispr Therapeutics AG(CRSP) | NAMEN AKT | H17182108 | $2.2M | 44,625 | 0.5% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $2.0M | 1,390,028 | 0.4% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $1.8M | 48,750 | 0.4% |
| Bicycle Therapeutics PLC(BCYC) | COM | 088786108 | $1.7M | 248,934 | 0.4% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $1.7M | 13,334 | 0.4% |
| Travere Therapeutics Inc(TVTX) | COM SHS | 89422G107 | $1.6M | 110,719 | 0.3% |
| Nuvation BIO Inc(NUVB) | ORD SHS | 67080N101 | $1.5M | 772,652 | 0.3% |
| Stoke Therapeutics Inc(STOK) | COM PAR $0.01 | 86150R107 | $1.4M | 125,861 | 0.3% |
| Pyxis Oncology Inc(PYXS) | COM | 747324101 | $1.1M | 1,037,421 | 0.2% |
| Humana Inc(HUM) | COM | 444859102 | $974.3K | 3,985 | 0.2% |
| Aldeyra Therapeutics Inc(ALDX) | SPONSORED ADR | 01438T106 | $863.5K | 225,465 | 0.2% |
| Karyopharm Therapeutics Inc(KPTI) | COM | 48576U205 | $809.9K | 187,911 | 0.2% |
| Vyne Therapeutics Inc Pipe(VYNE) | COM | 92941V308 | $735.0K | 445,434 | 0.2% |
| Abeona Therapeutics Inc(ABEO) | COM NEW | 00289Y206 | $618.4K | 108,865 | 0.1% |
| Alumis Inc(ALMS) | COM | 022307102 | $430.3K | 143,437 | 0.1% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $335.7K | 24,500 | 0.1% |
| Akari Therapeutics PLC(AKTX) | COM | 00972G207 | $170.8K | 146,024 | 0.0% |
| Generation BIO Co(GBIOGBX) | COM | 37148K100 | $48.2K | 150,475 | 0.0% |