Q4 2025 Holdings
Filed 2026-02-17 | 370 holdings | $8.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr S&P 500 ETF TR(SPY)Put | TR UNIT | 78462F103 | $2.0B | 3,000,000 | 24.3% |
| Ishares TR(IWM)Put | RUSSELL 2000 ETF | 464287655 | $2.0B | 8,100,000 | 23.7% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $212.8M | 2,801,869 | 2.5% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $154.7M | 265,705 | 1.8% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $146.1M | 5,747,155 | 1.7% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $143.8M | 3,763,891 | 1.7% |
| Supernus Pharmaceuticals Inc(SUPN) | COM | 868459108 | $137.4M | 2,764,000 | 1.6% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $116.3M | 820,240 | 1.4% |
| Incyte Corp(INCY) | COM | 45337C102 | $108.5M | 1,098,102 | 1.3% |
| Cytokinetics Inc(CYTK)Call | COM NEW | 23282W605 | $95.3M | 1,500,000 | 1.1% |
| Amazon COM Inc(AMZN) | COM | 023135106 | $84.9M | 367,633 | 1.0% |
| Dentsply Sirona Inc(XRAY) | COM | 24906P109 | $83.4M | 7,298,000 | 1.0% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $82.6M | 3,036,000 | 1.0% |
| Agios Pharmaceuticals Inc(AGIO)Call | COM | 00847X104 | $81.7M | 3,000,000 | 1.0% |
| Freshpet Inc(FRPT) | COM | 358039105 | $79.0M | 1,296,000 | 0.9% |
| Kenvue Inc(KVUE) | COM | 49177J102 | $68.9M | 3,992,196 | 0.8% |
| GE Healthcare Technologies I(GEHC) | COMMON STOCK | 36266G107 | $65.0M | 792,000 | 0.8% |
| Regeneron Pharmaceuticals(REGN) | COM | 75886F107 | $64.8M | 84,000 | 0.8% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $63.6M | 3,249,708 | 0.8% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $63.1M | 992,766 | 0.8% |
| Alphabet Inc(GOOGL) | CAP STK CL A | 02079K305 | $61.5M | 196,420 | 0.7% |
| Microsoft Corp(MSFT) | COM | 594918104 | $57.2M | 118,337 | 0.7% |
| Ironwood Pharmaceuticals Inc(IRWD) | COM CL A | 46333X108 | $54.0M | 16,025,000 | 0.6% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $51.3M | 4,936,000 | 0.6% |
| E L F Beauty Inc(ELF) | COM | 26856L103 | $50.0M | 657,983 | 0.6% |
| GSK PLC(GSK) | SPONSORED ADR | 37733W204 | $49.0M | 1,000,000 | 0.6% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $48.8M | 58,000 | 0.6% |
| Sentinelone Inc(S)Call | CL A | 81730H109 | $48.0M | 3,200,000 | 0.6% |
| Alibaba Group Hldg LTD(BABA) | SPONSORED ADS | 01609W102 | $46.8M | 319,100 | 0.6% |
| Starbucks Corp(SBUX) | COM | 855244109 | $46.3M | 549,805 | 0.6% |
| Penn Entertainment Inc(PENN) | COM | 707569109 | $45.7M | 3,096,000 | 0.5% |
| Orthofix MED Inc(OFIX) | COM | 68752M108 | $40.1M | 2,648,000 | 0.5% |
| Five9 Inc(FIVN) | COM | 338307101 | $40.1M | 2,000,000 | 0.5% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $39.7M | 499,391 | 0.5% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $38.1M | 1,098,000 | 0.5% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $36.4M | 62,838 | 0.4% |
| Sentinelone Inc(S) | CL A | 81730H109 | $36.3M | 2,422,219 | 0.4% |
| Five9 Inc(FIVN)Call | COM | 338307101 | $36.1M | 1,800,000 | 0.4% |
| Avanos MED Inc(AVNS) | COM | 05350V106 | $35.9M | 3,200,000 | 0.4% |
| Rigel Pharmaceuticals Inc(RIGL) | COM | 766559702 | $35.8M | 836,000 | 0.4% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $34.8M | 17,500,000 | 0.4% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $34.6M | 61,073 | 0.4% |
| Datadog Inc(DDOG) | CL A COM | 23804L103 | $33.3M | 244,537 | 0.4% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $33.1M | 653,796 | 0.4% |
| Sanofi SA(SNY) | SPONSORED ADR | 80105N105 | $32.8M | 676,000 | 0.4% |
| Gitlab Inc(GTLB) | CLASS A COM | 37637K108 | $32.2M | 858,925 | 0.4% |
| Axogen Inc(AXGN) | COM | 05463X106 | $30.6M | 936,000 | 0.4% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $27.3M | 1,536,000 | 0.3% |
| Verastem Inc(VSTM) | COM NEW | 92337C203 | $27.3M | 3,536,000 | 0.3% |
| Hubspot Inc(HUBS) | COM | 443573100 | $27.3M | 68,000 | 0.3% |