Q4 2022 Holdings
Filed 2023-02-14 | 86 holdings | $414.5M | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Madrigal Pharmaceuticals Inc(MDGL)Put | COM | 558868105 | $87.1M | 300,000 | 21.0% |
| Prometheus Biosciences Inc | COM | 74349U108 | $31.8M | 288,926 | 7.7% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $17.2M | 966,700 | 4.1% |
| Krystal Biotech Inc(KRYS)Put | COM | 501147102 | $13.1M | 165,900 | 3.2% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $12.0M | 250,000 | 2.9% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $11.9M | 267,476 | 2.9% |
| Esperion Therapeutics Inc NE(ESPR) | COM | 29664W105 | $11.8M | 1,891,147 | 2.8% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $11.6M | 837,500 | 2.8% |
| Prometheus Biosciences IncCall | COM | 74349U108 | $11.0M | 100,000 | 2.7% |
| Horizon Therapeutics PUB L | SHS | G46188101 | $10.2M | 89,219 | 2.4% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $10.1M | 675,176 | 2.4% |
| Altimmune Inc(ALT)Call | COM NEW | 02155H200 | $9.5M | 577,400 | 2.3% |
| Spdr SER TR(XBI)Call | S&P BIOTECH | 78464A870 | $8.3M | 100,000 | 2.0% |
| Spdr SER TR(XBI)Put | S&P BIOTECH | 78464A870 | $8.3M | 100,000 | 2.0% |
| Esperion Therapeutics Inc NE(ESPR)Call | COM | 29664W105 | $8.1M | 1,296,900 | 1.9% |
| Iveric BIO Inc(OPHTEUR) | COM | 46583P102 | $8.1M | 377,021 | 1.9% |
| Reata Pharmaceuticals Inc(RETAEUR)Put | CL A | 75615P103 | $7.6M | 201,200 | 1.8% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $7.5M | 737,319 | 1.8% |
| Bellus Health Inc New(BLU) | COM NEW | 07987C204 | $7.3M | 885,334 | 1.8% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $6.7M | 255,131 | 1.6% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $6.3M | 160,486 | 1.5% |
| Deciphera Pharmaceuticals in(DCPHEUR) | COM | 24344T101 | $6.0M | 367,119 | 1.5% |
| Arcus Biosciences Inc(RCUS)Put | COM | 03969F109 | $5.9M | 283,100 | 1.4% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $5.8M | 454,000 | 1.4% |
| Bluebird BIO Inc | COM | 09609G100 | $5.6M | 812,628 | 1.4% |
| Bioxcel Therapeutics Inc(BTAIEUR) | COM | 09075P105 | $5.4M | 250,000 | 1.3% |
| Verona Pharma PLC(VRNA)Call | SPONSORED ADS | 925050106 | $5.2M | 200,000 | 1.3% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $5.2M | 325,000 | 1.2% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $4.9M | 108,100 | 1.2% |
| Altimmune Inc(ALT) | COM NEW | 02155H200 | $4.5M | 273,432 | 1.1% |
| Kezar Life Sciences Inc | COM | 49372L100 | $4.4M | 629,986 | 1.1% |
| Tracon Pharmaceuticals Inc | COM NEW | 89237H209 | $4.1M | 2,765,530 | 1.0% |
| Ardelyx Inc(ARDX) | COM | 039697107 | $3.9M | 1,378,825 | 0.9% |
| Aerovate Therapeutics Inc | COM | 008064107 | $3.7M | 127,921 | 0.9% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $3.7M | 28,324 | 0.9% |
| Arvinas Inc(ARVN)Call | COM | 04335A105 | $3.4M | 100,000 | 0.8% |
| Seagen Inc(SGENUSD) | COM | 81181C104 | $3.2M | 25,000 | 0.8% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $2.9M | 137,987 | 0.7% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $2.6M | 67,805 | 0.6% |
| Astria Therapeutics Inc(CATBUSD)Call | COM | 04635X102 | $2.5M | 171,100 | 0.6% |
| Merus N V | COM | N5749R100 | $2.4M | 156,000 | 0.6% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $1.9M | 203,156 | 0.5% |
| Milestone Pharmaceuticals in(MIST) | COM | 59935V107 | $1.8M | 460,416 | 0.4% |
| Geron Corp(GERN)Call | COM | 374163103 | $1.6M | 650,000 | 0.4% |
| Proqr Thrapeutics N V | SHS EURO | N71542109 | $1.6M | 422,625 | 0.4% |
| Acumen Pharmaceuticals Inc(ABOS) | COM | 00509G209 | $1.4M | 254,945 | 0.3% |
| ARK ETF TR(ARKG) | GENOMIC REV ETF | 00214Q302 | $1.3M | 46,462 | 0.3% |
| Lyra Therapeutics Inc(LYRA) | COM | 55234L105 | $1.1M | 343,685 | 0.3% |
| Intercept Pharmaceuticals in(ICPTUSD) | COM | 45845P108 | $1.1M | 85,200 | 0.3% |
| Point Biopharma Global Inc | COM | 730541109 | $1.0M | 139,565 | 0.2% |