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Ikarian Capital, LLC

Q1 2025 Holdings

Filed 2025-05-15 | 160 holdings | $811.5M | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↓Shares% Portfolio
Spdr S&P 500 ETF TR(SPY)PutTR UNIT78462F103$179.0M320,00022.1%
ELI Lilly & Co(LLY)PutCOM532457108$123.9M150,00015.3%
Corcept Therapeutics Inc(CORT)PutCOM218352102$32.9M287,9004.1%
Tarsus Pharmaceuticals Inc(TARS)COM87650L103$24.9M485,0213.1%
Bridgebio Pharma Inc(BBIO)CallCOM10806X102$22.7M655,4002.8%
Crinetics Pharmaceuticals in(CRNX)COM22663K107$17.6M523,4312.2%
Soleno Therapeutics Inc(SLNO)CallCOM834203309$17.4M243,0002.1%
Spdr S&P 500 ETF TR(SPY)TR UNIT78462F103$14.0M25,0001.7%
Corcept Therapeutics Inc(CORT)CallCOM218352102$11.4M100,0001.4%
Sarepta Therapeutics Inc(SRPT)COM803607100$10.8M169,0871.3%
Blueprint Medicines Corp(2L9)COM09627Y109$10.1M113,9041.2%
Akero Therapeutics Inc(AKRO)COM00973Y108$9.9M245,0001.2%
Avidity Biosciences Inc(RNA)PutCOM05370A108$8.9M300,0001.1%
Alnylam Pharmaceuticals Inc(ALNY)COM02043Q107$8.5M31,5941.1%
Biohaven LTD(BHVN)CallCOMG1110E107$8.4M348,2001.0%
TG Therapeutics Inc(TGTX)COM88322Q108$8.3M210,0651.0%
Verona Pharma PLC(VRNA)SPONSORED ADS925050106$8.3M130,0001.0%
Ultragenyx Pharmaceutical in(RARE)COM90400D108$7.9M216,9891.0%
Scholar Rock Hldg Corp(SRRK)COM80706P103$7.9M244,1791.0%
Vaxcyte Inc(PCVX)COM92243G108$7.6M200,0000.9%
Trupanion Inc(TRUP)CallCOM898202106$7.5M200,0000.9%
Arcellx Inc(ACLX)PutCOMMON STOCK03940C100$7.3M111,6000.9%
Soleno Therapeutics Inc(SLNO)PutCOM834203309$7.1M100,0000.9%
VIR Biotechnology Inc(VIR)COM92764N102$6.9M1,068,0620.9%
Immunovant Inc(IMVT)PutCOM45258J102$6.8M400,0000.8%
Viridian Therapeutics Inc(VRDN)COM92790C104$6.7M494,9490.8%
Insmed Inc(INSM)COM PAR $.01457669307$6.5M84,8000.8%
Edgewise Therapeutics Inc(EWTX)COM28036F105$6.2M280,0000.8%
Catalyst Pharmaceuticals Inc(CPRX)COM14888U101$6.1M249,6490.7%
Cytokinetics Inc(CYTK)COM NEW23282W605$6.0M149,9820.7%
Enliven Therapeutics Inc(ELVN)COM29337E102$5.7M289,5380.7%
Praxis Precision Medicines I(PRAX)COM NEW74006W207$5.5M145,5020.7%
Cidara Therapeutics Inc(CDTX)COM NEW171757206$5.4M248,9400.7%
Alpha Cognition Inc(ACOG)COM NEW02074J501$5.1M967,8670.6%
Kymera Therapeutics Inc(KYMR)PutCOM501575104$4.8M176,8000.6%
Protagonist Therapeutics Inc(PTGX)CallCOM74366E102$4.8M100,0000.6%
Protagonist Therapeutics Inc(PTGX)PutCOM74366E102$4.8M100,0000.6%
Tectonic Therapeutic Inc(TECX)COM878972108$4.8M269,0900.6%
Forte Biosciences Inc(FBRX)COM NEW34962G208$4.7M609,2250.6%
Structure Therapeutics Inc(GPCR)SPONSORED ADS86366E106$4.6M264,0850.6%
Ultragenyx Pharmaceutical in(RARE)CallCOM90400D108$4.1M113,1000.5%
Metsera IncCOM59267L107$4.1M150,0000.5%
Neuronetics Inc(STIM)COM64131A105$4.0M1,100,0000.5%
Capricor Therapeutics Inc(CAPR)CallCOM NEW14070B309$3.8M400,0000.5%
Dyne Therapeutics Inc(DYN)COM26818M108$3.8M358,8370.5%
Moonlake Immunotherapeutics(MLTX)CallCLASS A ORD61559X104$3.7M94,5000.5%
Moonlake Immunotherapeutics(MLTX)PutCLASS A ORD61559X104$3.7M94,5000.5%
Incyte Corp(INCY)CallCOM45337C102$3.7M60,4000.5%
Viking Therapeutics Inc(VKTX)CallCOM92686J106$3.6M150,0000.4%
Ultragenyx Pharmaceutical in(RARE)PutCOM90400D108$3.6M100,0000.4%
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