Q4 2021 Holdings
Filed 2022-02-14 | 124 holdings | $1.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $335.1M | 1,975,879 | 31.4% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $151.5M | 3,921,579 | 14.2% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $116.7M | 2,561,182 | 10.9% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $111.2M | 317,447 | 10.4% |
| C4 Therapeutics Inc(CCCC) | COM STK | 12529R107 | $80.3M | 2,494,965 | 7.5% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $61.2M | 1,618,819 | 5.7% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $52.9M | 869,271 | 5.0% |
| Apyx Medical Corporation(APYX) | COM | 03837C106 | $43.6M | 3,398,279 | 4.1% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $26.1M | 6,029,700 | 2.4% |
| Castle Biosciences Inc(CSTL) | COM | 14843C105 | $25.7M | 599,009 | 2.4% |
| Arrowhead Pharmaceuticals in(ARWR) | COM | 04280A100 | $23.0M | 346,842 | 2.2% |
| Aadi Biosciences Inc(WHWK) | COM | 00032Q104 | $18.5M | 764,701 | 1.7% |
| Arbutus Biopharma Corp(ABUS) | COM | 03879J100 | $9.7M | 2,504,493 | 0.9% |
| Biomea Fusion Inc(BMEA) | COM | 09077A106 | $4.4M | 593,846 | 0.4% |
| Avita Medical Inc(RCEL) | COM | 05380C102 | $1.3M | 106,667 | 0.1% |
| Spdr S&P 500 ETF TR(SPY) | TR UNIT | 78462F103 | $422.6K | 889,739 | 0.0% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $345.0K | 15,802,802 | 0.0% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $290.6K | 435,500 | 0.0% |
| Masimo Corp(MASI) | COM | 574795100 | $248.9K | 849,971 | 0.0% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $229.1K | 1,561,497 | 0.0% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $210.9K | 5,293,966 | 0.0% |
| Illumina Inc(ILMN) | COM | 452327109 | $186.6K | 490,399 | 0.0% |
| Penumbra Inc(PEN) | COM | 70975L107 | $178.4K | 620,871 | 0.0% |
| Vericel Corp(VCEL) | COM | 92346J108 | $177.5K | 4,517,570 | 0.0% |
| Tandem Diabetes Care Inc(TNDM) | COM NEW | 875372203 | $174.7K | 1,160,734 | 0.0% |
| Natera Inc(NTRA) | COM | 632307104 | $173.9K | 1,862,234 | 0.0% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $156.8K | 2,319,138 | 0.0% |
| Prometheus Biosciences Inc | COM | 74349U108 | $129.1K | 3,264,031 | 0.0% |
| Globus MED Inc(GMED) | CL A | 379577208 | $120.6K | 1,670,811 | 0.0% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $115.5K | 1,373,284 | 0.0% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $114.0K | 4,795,000 | 0.0% |
| Iveric BIO Inc(OPHTEUR) | COM | 46583P102 | $112.4K | 6,722,624 | 0.0% |
| Iteos Therapeutics Inc(5E7) | COM | 46565G104 | $109.6K | 2,353,015 | 0.0% |
| 10X Genomics Inc(TXG) | CL A COM | 88025U109 | $109.4K | 734,481 | 0.0% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $108.9K | 1,943,864 | 0.0% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $94.1K | 1,990,404 | 0.0% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $88.9K | 2,599,822 | 0.0% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $87.4K | 3,644,248 | 0.0% |
| Guardant Health Inc(GH) | COM | 40131M109 | $81.4K | 813,342 | 0.0% |
| PMV Pharmaceuticals Inc(PMVP) | COM | 69353Y103 | $68.9K | 2,980,960 | 0.0% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $68.4K | 3,866,872 | 0.0% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $63.8K | 3,975,554 | 0.0% |
| Regenxbio Inc(RGNX) | COM | 75901B107 | $60.3K | 1,845,366 | 0.0% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $59.6K | 2,520,076 | 0.0% |
| Cutera Inc(CUTREUR) | COM | 232109108 | $57.7K | 1,397,063 | 0.0% |
| Proqr Thrapeutics N V | SHS EURO | N71542109 | $56.3K | 7,027,725 | 0.0% |
| Adicet BIO Inc(TORCEUR) | COM | 007002108 | $52.9K | 3,023,744 | 0.0% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $52.4K | 582,265 | 0.0% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $50.6K | 2,168,957 | 0.0% |
| Science 37 Holdings Inc | COM | 808644108 | $49.6K | 3,975,000 | 0.0% |