Q3 2023 Holdings
Filed 2023-11-14 | 67 holdings | $4.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $362.4M | 17,687,772 | 7.6% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $316.4M | 6,096,387 | 6.7% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $313.8M | 4,489,596 | 6.6% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $298.1M | 1,683,362 | 6.3% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $294.8M | 6,768,514 | 6.2% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $249.4M | 507,195 | 5.3% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $241.3M | 11,576,537 | 5.1% |
| Bruker Corp(BRKR) | COM | 116794108 | $210.7M | 3,381,703 | 4.4% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $192.7M | 5,405,089 | 4.1% |
| Penumbra Inc(PEN) | COM | 70975L107 | $162.9M | 673,371 | 3.4% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $162.1M | 7,235,196 | 3.4% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $147.0M | 290,334 | 3.1% |
| Masimo Corp(MASI) | COM | 574795100 | $131.7M | 1,501,493 | 2.8% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $122.4M | 2,494,138 | 2.6% |
| Natera Inc(NTRA) | COM | 632307104 | $117.3M | 2,651,783 | 2.5% |
| Vericel Corp(VCEL) | COM | 92346J108 | $110.3M | 3,291,873 | 2.3% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $106.0M | 5,149,482 | 2.2% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $95.3M | 3,463,201 | 2.0% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $90.3M | 5,415,514 | 1.9% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $75.8M | 2,574,198 | 1.6% |
| Avadel Pharmaceuticals PLC | SPONSORED ADR | 05337M104 | $73.5M | 7,136,415 | 1.6% |
| 10X Genomics Inc(TXG) | CL A COM | 88025U109 | $62.7M | 1,519,956 | 1.3% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $53.4M | 16,893,185 | 1.1% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $51.2M | 2,880,701 | 1.1% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $49.0M | 5,620,640 | 1.0% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $47.1M | 1,865,108 | 1.0% |
| Merus N V | COM | N5749R100 | $47.1M | 1,996,764 | 1.0% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $45.6M | 2,142,591 | 1.0% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $45.2M | 309,485 | 1.0% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $42.7M | 6,689,789 | 0.9% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $33.4M | 3,327,129 | 0.7% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $28.5M | 500,000 | 0.6% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $25.8M | 5,818,804 | 0.5% |
| Illumina Inc(ILMN) | COM | 452327109 | $25.8M | 188,125 | 0.5% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $24.9M | 889,073 | 0.5% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $24.8M | 442,487 | 0.5% |
| Shockwave MED Inc(SWAVUSD) | COM | 82489T104 | $24.7M | 124,000 | 0.5% |
| Scpharmaceuticals Inc(SCPH) | COM | 810648105 | $23.5M | 3,297,843 | 0.5% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $18.1M | 1,552,717 | 0.4% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $17.3M | 4,390,558 | 0.4% |
| Allurion Technologies Inc | COM SHS | 02008G102 | $14.9M | 3,457,707 | 0.3% |
| Guardant Health Inc(GH) | COM | 40131M109 | $14.8M | 500,887 | 0.3% |
| PMV Pharmaceuticals Inc(PMVP) | COM | 69353Y103 | $14.6M | 2,375,785 | 0.3% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $12.0M | 857,464 | 0.3% |
| Cutera Inc(CUTREUR) | COM | 232109108 | $11.1M | 1,846,596 | 0.2% |
| Milestone Pharmaceuticals in(MIST) | COM | 59935V107 | $10.1M | 3,256,102 | 0.2% |
| Acelyrin Inc | COM | 00445A100 | $9.9M | 978,310 | 0.2% |
| Immatics N.v(IMTX) | SHS | N44445109 | $9.8M | 845,000 | 0.2% |
| Outset MED Inc(OMGBP) | COM | 690145107 | $8.8M | 808,658 | 0.2% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $8.8M | 922,100 | 0.2% |