Q4 2025 Holdings
Filed 2026-02-17 | 30 holdings | $3.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Nuvalent Inc(NUVL) | COM | 670703107 | $530.1M | 5,269,433 | 13.5% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $529.2M | 6,644,403 | 13.5% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $373.2M | 5,724,016 | 9.5% |
| Genmab A/S(GMAB) | SPONSORED ADS | 372303206 | $216.8M | 7,039,834 | 5.5% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $209.8M | 2,562,154 | 5.4% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $191.2M | 1,417,473 | 4.9% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $188.6M | 7,544,172 | 4.8% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $187.7M | 4,068,020 | 4.8% |
| Spdr Series Trust(XBI)Put | STATE STREET SPD | 78464A870 | $182.9M | 1,500,000 | 4.7% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $167.8M | 759,565 | 4.3% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $162.3M | 6,541,210 | 4.1% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $134.9M | 3,062,157 | 3.4% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $104.8M | 4,473,648 | 2.7% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $102.9M | 2,210,774 | 2.6% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $84.8M | 1,123,243 | 2.2% |
| Eyepoint Inc(EYPT) | COM NEW | 30233G209 | $67.4M | 3,691,475 | 1.7% |
| Erasca Inc(ERAS) | COM | 29479A108 | $52.7M | 14,159,095 | 1.3% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $52.3M | 684,277 | 1.3% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $51.8M | 1,710,316 | 1.3% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $48.1M | 1,467,266 | 1.2% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $47.3M | 4,763,198 | 1.2% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $44.9M | 1,443,102 | 1.1% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $35.6M | 2,935,284 | 0.9% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $32.7M | 810,286 | 0.8% |
| Bridgebio Oncology Therapeut(BBOT) | COM NEW | 107924102 | $28.3M | 2,261,749 | 0.7% |
| VOR Biopharma Inc(VOR) | COM NEW | 929033207 | $22.9M | 1,750,000 | 0.6% |
| Assembly Biosciences Inc(ASMB) | COM NEW | 045396207 | $22.6M | 665,251 | 0.6% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $19.6M | 2,401,217 | 0.5% |
| Inventiva SA(IVA) | ADS | 46124U107 | $18.6M | 4,000,000 | 0.5% |
| Kalaris Therapeutics Inc(KLRS) | COM | 482929106 | $5.9M | 700,000 | 0.2% |