Q1 2023 Holdings
Filed 2023-05-15 | 58 holdings | $2.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $175.6M | 1,200,000 | 7.2% |
| Iveric BIO Inc(OPHTEUR) | COM | 46583P102 | $158.1M | 6,500,000 | 6.5% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $138.3M | 6,147,268 | 5.7% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $115.3M | 7,432,717 | 4.7% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $110.8M | 6,500,000 | 4.6% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $101.3M | 2,834,069 | 4.2% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $92.1M | 1,700,000 | 3.8% |
| Pliant Therapeutics Inc(PLRX) | COM | 729139105 | $91.0M | 3,422,057 | 3.7% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $84.6M | 3,000,000 | 3.5% |
| Springworks Therapeutics Inc | COM | 85205L107 | $79.8M | 3,100,000 | 3.3% |
| Chinook Therapeutics Inc(290A) | COM | 16961L106 | $69.5M | 3,000,000 | 2.9% |
| Reata Pharmaceuticals Inc(RETAEUR) | CL A | 75615P103 | $66.3M | 729,000 | 2.7% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $64.0M | 3,187,415 | 2.6% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $63.0M | 2,646,782 | 2.6% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $62.3M | 6,350,000 | 2.6% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $60.0M | 2,819,045 | 2.5% |
| Geron Corp(GERN) | COM | 374163103 | $58.3M | 26,867,479 | 2.4% |
| Biogen Inc(BIIB) | COM | 09062X103 | $55.6M | 200,000 | 2.3% |
| Dice Therapeutics Inc | COM | 23345J104 | $45.8M | 1,600,000 | 1.9% |
| Agenus Inc(AGENEUR) | COM NEW | 00847G705 | $45.6M | 30,000,000 | 1.9% |
| Seagen Inc(SGENUSD)Put | COM | 81181C104 | $44.1M | 217,800 | 1.8% |
| Pacific Biosciences Calif in(PACB) | COM | 69404D108 | $40.6M | 3,504,390 | 1.7% |
| 4D Molecular Therapeutics in(FDMT) | COM | 35104E100 | $39.2M | 2,278,107 | 1.6% |
| Beam Therapeutics Inc(BEAM) | COM | 07373V105 | $38.3M | 1,250,000 | 1.6% |
| Exelixis Inc(EXEL) | COM | 30161Q104 | $37.5M | 1,931,874 | 1.5% |
| Argenx SE(ARGX)Put | SPONSORED ADR | 04016X101 | $37.3M | 100,000 | 1.5% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $31.3M | 1,230,259 | 1.3% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $27.6M | 15,000,000 | 1.1% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $27.4M | 1,800,000 | 1.1% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $26.9M | 2,334,633 | 1.1% |
| Repare Therapeutics Inc(RPTX) | COM | 760273102 | $26.8M | 2,727,606 | 1.1% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $26.6M | 2,997,830 | 1.1% |
| Intellia Therapeutics Inc(NTLA) | COM | 45826J105 | $26.3M | 704,533 | 1.1% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $24.2M | 1,816,531 | 1.0% |
| Deciphera Pharmaceuticals in(DCPHEUR) | COM | 24344T101 | $21.1M | 1,363,201 | 0.9% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $20.5M | 3,068,259 | 0.8% |
| Vigil Neuroscience Inc(VIGL) | COM | 92673K108 | $19.8M | 2,025,137 | 0.8% |
| Inozyme Pharma Inc | COM | 45790W108 | $18.6M | 3,250,000 | 0.8% |
| Uniqure NV(QURE) | SHS | N90064101 | $17.4M | 865,767 | 0.7% |
| Point Biopharma Global Inc | COM | 730541109 | $17.0M | 2,345,073 | 0.7% |
| Acumen Pharmaceuticals Inc(ABOS) | COM | 00509G209 | $16.0M | 3,952,000 | 0.7% |
| Allakos Inc(ALLKGUSD) | COM | 01671P100 | $16.0M | 3,585,000 | 0.7% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $13.8M | 1,708,971 | 0.6% |
| Nuvation BIO Inc(NUVB) | COM CL A | 67080N101 | $12.8M | 7,720,688 | 0.5% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $12.1M | 1,951,580 | 0.5% |
| Rapt Therapeutics Inc(RAPTEUR) | COM | 75382E109 | $10.5M | 571,233 | 0.4% |
| Jounce Therapeutics Inc(JNCEEUR) | COM | 481116101 | $7.9M | 4,259,653 | 0.3% |
| Relmada Therapeutics Inc(RLMD) | COM | 75955J402 | $6.4M | 2,837,818 | 0.3% |
| Orchard Therapeutics PLC | SPON ADS NEW | 68570P200 | $6.3M | 1,166,670 | 0.3% |
| Heron Therapeutics Inc(HRTX) | COM | 427746102 | $4.9M | 3,234,722 | 0.2% |