Q4 2023 Holdings
Filed 2024-02-14 | 60 holdings | $3.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $165.8M | 5,350,000 | 5.5% |
| Springworks Therapeutics Inc | COM | 85205L107 | $148.3M | 4,063,676 | 5.0% |
| Intra-Cellular Therapies Inc(ITCIEUR) | COM | 46116X101 | $143.2M | 2,000,000 | 4.8% |
| Guardant Health Inc(GH) | COM | 40131M109 | $135.3M | 5,000,000 | 4.5% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $114.1M | 300,000 | 3.8% |
| Cytokinetics Inc(CYTK)Call | COM NEW | 23282W605 | $112.5M | 1,347,300 | 3.8% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $111.0M | 4,000,000 | 3.7% |
| Pliant Therapeutics Inc(PLRX) | COM | 729139105 | $104.1M | 5,750,000 | 3.5% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $99.2M | 7,093,214 | 3.3% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $79.6M | 1,000,000 | 2.7% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $79.1M | 3,631,728 | 2.6% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $76.4M | 11,869,297 | 2.6% |
| Pacific Biosciences Calif in(PACB) | COM | 69404D108 | $68.7M | 7,000,000 | 2.3% |
| Intellia Therapeutics Inc(NTLA) | COM | 45826J105 | $68.6M | 2,250,000 | 2.3% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $66.3M | 7,370,000 | 2.2% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $64.9M | 2,323,456 | 2.2% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $63.4M | 3,187,415 | 2.1% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $63.2M | 1,249,068 | 2.1% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $63.1M | 3,490,506 | 2.1% |
| Geron Corp(GERN) | COM | 374163103 | $62.4M | 29,583,449 | 2.1% |
| Editas Medicine Inc(EDIT) | COM | 28106W103 | $55.4M | 5,473,086 | 1.9% |
| Ambrx Biopharma Inc | COM | 641871108 | $52.8M | 3,710,412 | 1.8% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $48.2M | 500,000 | 1.6% |
| Tourmaline BIO Inc(TRML) | COM | 89157D105 | $47.5M | 1,815,854 | 1.6% |
| Hillevax Inc | COM | 43157M102 | $46.5M | 2,900,000 | 1.6% |
| 4D Molecular Therapeutics in(FDMT) | COM | 35104E100 | $46.3M | 2,284,372 | 1.5% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $46.0M | 4,297,438 | 1.5% |
| Rapt Therapeutics Inc(RAPTEUR) | COM | 75382E109 | $44.6M | 1,793,966 | 1.5% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $43.6M | 2,036,990 | 1.5% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $42.1M | 1,000,000 | 1.4% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $42.0M | 1,952,760 | 1.4% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $41.2M | 9,230,769 | 1.4% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $40.2M | 725,145 | 1.3% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $39.6M | 6,100,000 | 1.3% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $33.9M | 1,951,580 | 1.1% |
| Orchard Therapeutics PLC | SPON ADS NEW | 68570P200 | $33.6M | 2,041,670 | 1.1% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $33.1M | 450,000 | 1.1% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $33.1M | 600,000 | 1.1% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $30.9M | 2,997,830 | 1.0% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $27.8M | 2,537,176 | 0.9% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $27.1M | 1,930,894 | 0.9% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $26.6M | 2,000,000 | 0.9% |
| Agenus Inc(AGENEUR) | COM NEW | 00847G705 | $26.2M | 31,697,539 | 0.9% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $24.1M | 288,949 | 0.8% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $23.7M | 1,062,881 | 0.8% |
| Repare Therapeutics Inc(RPTX) | COM | 760273102 | $21.8M | 2,992,731 | 0.7% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $19.0M | 1,011,829 | 0.6% |
| Prothena Corp PLC(PRTA)Call | SHS | G72800108 | $18.2M | 500,000 | 0.6% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $12.2M | 300,000 | 0.4% |
| Zura BIO LTD(ZURA) | CLASS A ORD SHS | G9TY5A101 | $11.8M | 2,523,000 | 0.4% |