Q3 2025 Holdings
Filed 2025-11-14 | 56 holdings | $3.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Guardant Health Inc(GH) | COM | 40131M109 | $259.5M | 4,154,086 | 7.2% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $249.1M | 3,808,144 | 7.0% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $236.3M | 4,300,000 | 6.6% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $190.0M | 4,000,978 | 5.3% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $181.0M | 8,000,382 | 5.1% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $178.3M | 3,000,000 | 5.0% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $156.8M | 9,728,845 | 4.4% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $156.2M | 15,726,349 | 4.4% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $139.5M | 11,932,137 | 3.9% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $137.5M | 9,356,171 | 3.8% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $118.0M | 4,215,811 | 3.3% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $116.1M | 5,380,449 | 3.2% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $114.0M | 1,715,691 | 3.2% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $109.3M | 900,000 | 3.1% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $108.1M | 3,000,000 | 3.0% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $102.4M | 3,948,910 | 2.9% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $65.4M | 1,800,000 | 1.8% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $62.3M | 1,200,000 | 1.7% |
| Geron Corp(GERN) | COM | 374163103 | $56.3M | 41,096,522 | 1.6% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $56.3M | 7,495,000 | 1.6% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $56.0M | 6,057,024 | 1.6% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $55.1M | 3,150,000 | 1.5% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $54.7M | 1,000,000 | 1.5% |
| LB Pharmaceuticals Inc(LBRX) | COM SHS | 50180M108 | $52.9M | 3,352,804 | 1.5% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $51.7M | 2,000,000 | 1.4% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $51.1M | 2,654,781 | 1.4% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $48.2M | 1,200,000 | 1.3% |
| Compass Pathways PLC(CMPS) | SPONSORED ADS | 20451W101 | $45.0M | 7,859,648 | 1.3% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $41.2M | 450,000 | 1.2% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $38.3M | 2,426,657 | 1.1% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $34.0M | 3,470,172 | 0.9% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $28.7M | 300,000 | 0.8% |
| Uniqure NV(QURE) | SHS | N90064101 | $28.2M | 483,092 | 0.8% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $25.3M | 2,000,000 | 0.7% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $19.7M | 2,279,892 | 0.5% |
| Rapt Therapeutics Inc(RAPT) | COM NEW | 75382E208 | $19.4M | 751,422 | 0.5% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $17.9M | 1,250,000 | 0.5% |
| Mind Medicine Mindmed Inc(BRD1EUR) | COM NEW | 60255C885 | $17.7M | 1,500,000 | 0.5% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $15.3M | 2,239,353 | 0.4% |
| Genmab A/S(GMAB) | SPONSORED ADS | 372303206 | $14.8M | 481,267 | 0.4% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $12.2M | 1,454,562 | 0.3% |
| Context Therapeutics Inc(CNTX) | COM | 21077P108 | $7.2M | 7,419,355 | 0.2% |
| Imagenebio Inc(IMA) | COM | 45175G207 | $7.2M | 878,516 | 0.2% |
| Xencor Inc(XNCR) | COM | 98401F105 | $6.4M | 549,439 | 0.2% |
| Cybin Inc(HELP) | COM NEW | 23256X407 | $5.9M | 1,000,000 | 0.2% |
| Cormedix Inc(CRMD) | COM | 21900C308 | $5.8M | 500,000 | 0.2% |
| Pepgen Inc(PEPG) | COM | 713317105 | $5.5M | 1,200,000 | 0.2% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $5.4M | 453,686 | 0.2% |
| Aligos Therapeutics Inc(ALGS) | COM NEW | 01626L204 | $4.4M | 444,110 | 0.1% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $4.2M | 2,568,613 | 0.1% |