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Diadema Partners LP

Q4 2025 Holdings

Filed 2026-02-17 | 145 holdings | $580.5M | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↓Shares% Portfolio
Vertex Pharmaceuticals Inc(VRTX)CallCOM92532F100$40.0M88,3006.9%
Spdr Series Trust(XBI)PutSTATE STREET SPD78464A870$30.5M250,0005.3%
Praxis Precision Medicines I(PRAX)PutCOM NEW74006W207$29.7M100,6005.1%
Viking Therapeutics Inc(VKTX)CallCOM92686J106$24.2M688,9004.2%
Avidity Biosciences Inc(RNA)CallCOM05370A108$23.7M328,0004.1%
Invesco QQQ TR(QQQ)PutUNIT SER 146090E103$18.4M30,0003.2%
Jazz Pharmaceuticals PLC(JAZZ)CallSHS USDG50871105$17.9M105,3003.1%
Apogee Therapeutics Inc(APGE)CallCOM03770N101$15.9M211,1002.7%
Bridgebio Pharma Inc(BBIO)PutCOM10806X102$15.3M200,0002.6%
Terns Pharmaceuticals Inc(TERN)COM880881107$14.0M345,8802.4%
Johnson & Johnson(JNJ)COM478160104$13.8M66,4442.4%
Structure Therapeutics Inc(GPCR)CallSPONSORED ADS86366E106$13.3M191,7002.3%
Viking Therapeutics Inc(VKTX)COM92686J106$11.9M336,8492.0%
Viking Therapeutics Inc(VKTX)PutCOM92686J106$11.1M316,7001.9%
Bridgebio Pharma Inc(BBIO)CallCOM10806X102$10.7M139,6001.8%
Johnson & Johnson(JNJ)CallCOM478160104$10.3M50,0001.8%
Abivax SA(ABVX)SPONSORED ADS00370M103$10.2M75,6441.8%
Incyte Corp(INCY)PutCOM45337C102$9.9M100,0001.7%
Insmed Inc(INSM)CallCOM PAR $.01457669307$9.2M52,8001.6%
Capricor Therapeutics Inc(CAPR)CallCOM NEW14070B309$9.0M312,3001.6%
Biomarin Pharmaceutical Inc(BMRN)COM09061G101$8.7M146,3611.5%
Ionis Pharmaceuticals Inc(IONS)CallCOM462222100$8.4M106,2001.4%
Regeneron Pharmaceuticals(REGN)COM75886F107$8.0M10,3001.4%
Indivior PLC(INDV)CallORDG4766E116$7.9M220,3001.4%
Uniqure NV(QURE)PutSHSN90064101$7.2M301,8001.2%
Roivant Sciences LTD(ROIV)PutSHSG76279101$6.9M318,7001.2%
Ocular Therapeutix Inc(OCUL)CallCOM67576A100$6.6M545,2001.1%
Zymeworks Inc(ZYME)CallCOM98985Y108$6.3M240,6001.1%
Crispr Therapeutics AG(CRSP)CallNAMEN AKTH17182108$5.9M112,7001.0%
Capricor Therapeutics Inc(CAPR)PutCOM NEW14070B309$5.8M200,0001.0%
Bridgebio Pharma Inc(BBIO)COM10806X102$5.4M70,0000.9%
United Therapeutics Corp del(UTHR)COM91307C102$4.9M10,0000.8%
Corcept Therapeutics Inc(CORT)PutCOM218352102$4.7M134,8000.8%
Cogent Biosciences Inc(COGT)COM19240Q201$4.7M131,8520.8%
Capricor Therapeutics Inc(CAPR)COM NEW14070B309$4.6M158,0750.8%
Vertex Pharmaceuticals Inc(VRTX)COM92532F100$4.5M10,0000.8%
ANI Pharmaceuticals Inc(ANIP)COM00182C103$4.2M53,3540.7%
Regeneron Pharmaceuticals(REGN)CallCOM75886F107$3.9M5,0000.7%
TG Therapeutics Inc(TGTX)COM88322Q108$3.7M123,2830.6%
Bioage Labs Inc(BIOA)COM09077V100$3.6M271,1640.6%
Corcept Therapeutics Inc(CORT)COM218352102$3.4M97,4450.6%
Mannkind Corp(MNKD)CallCOM NEW56400P706$3.1M552,3000.5%
Recursion Pharmaceuticals in(RXRX)CallCL A75629V104$3.0M741,9000.5%
TG Therapeutics Inc(TGTX)PutCOM88322Q108$3.0M100,0000.5%
Tenax Therapeutics Inc(TENX)COM NEW88032L605$3.0M243,1700.5%
Revolution Medicines Inc(RVMD)COM76155X100$2.9M37,0200.5%
Intellia Therapeutics Inc(NTLA)PutCOM45826J105$2.8M316,9000.5%
Gossamer BIO Inc(GOSS)CallCOM38341P102$2.7M877,1000.5%
Novo-Nordisk A S(NVO)PutADR670100205$2.7M53,1000.5%
Arbutus Biopharma Corp(ABUS)CallCOM03879J100$2.6M548,6000.5%
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