Q3 2025 Holdings
Filed 2025-11-14 | 51 holdings | $630.9M | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2025-11-14) | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $105.4M | 732,212 | 16.7% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $57.8M | 78,311 | 9.2% |
| Insmed Inc(INSM)Call | COM PAR $.01 | 457669307 | $57.6M | 400,000 | 9.1% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $45.4M | 672,176 | 7.2% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $40.4M | 379,004 | 6.4% |
| Uniqure NV(QURE) | SHS | N90064101 | $38.5M | 658,839 | 6.1% |
| Merus N V | COM | N5749R100 | $27.9M | 296,750 | 4.4% |
| Proshares TR II(UGL) | ULTRA GOLD | 74347W601 | $24.8M | 537,372 | 3.9% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $21.9M | 28,700 | 3.5% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $21.6M | 55,100 | 3.4% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $19.1M | 225,453 | 3.0% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $18.3M | 1,999,702 | 2.9% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $17.9M | 183,200 | 2.8% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $15.8M | 34,570 | 2.5% |
| Quest Diagnostics Inc(DGX) | COM | 74834L100 | $15.6M | 81,717 | 2.5% |
| Astrazeneca PLC(AZN) | SPONSORED ADR | 046353108 | $14.6M | 190,752 | 2.3% |
| Eyepoint Pharmaceuticals Inc(EYPT) | COM NEW | 30233G209 | $8.9M | 628,367 | 1.4% |
| Regeneron Pharmaceuticals(REGN) | COM | 75886F107 | $6.0M | 10,671 | 1.0% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $5.5M | 194,838 | 0.9% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $4.9M | 104,190 | 0.8% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $4.8M | 110,100 | 0.8% |
| Ultragenyx Pharmaceutical in(RARE)Call | COM | 90400D108 | $4.5M | 150,000 | 0.7% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $4.3M | 108,723 | 0.7% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $3.9M | 60,176 | 0.6% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $3.8M | 146,179 | 0.6% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $3.6M | 96,285 | 0.6% |
| Abbvie Inc(ABBV) | COM | 00287Y109 | $3.4M | 14,500 | 0.5% |
| Nektar Therapeutics(NKTR) | COM NEW | 640268306 | $3.3M | 57,999 | 0.5% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $3.2M | 133,291 | 0.5% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $2.4M | 12,240 | 0.4% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $2.1M | 56,600 | 0.3% |
| United Therapeutics Corp del(UTHR) | COM | 91307C102 | $2.1M | 5,000 | 0.3% |
| TG Therapeutics Inc(TGTX) | COM | 88322Q108 | $2.0M | 54,515 | 0.3% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $1.9M | 64,502 | 0.3% |
| Rapport Therapeutics Inc(RAPP) | COM | 75383L102 | $1.9M | 64,608 | 0.3% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $1.6M | 141,061 | 0.3% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $1.6M | 40,000 | 0.3% |
| Iren Limited(IREN) | ORDINARY SHARES | Q4982L109 | $1.6M | 33,200 | 0.2% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $1.5M | 22,951 | 0.2% |
| Brightspring Health Svcs Inc(BTSG) | COM | 10950A106 | $1.2M | 41,600 | 0.2% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $1.2M | 80,000 | 0.2% |
| Kiniksa Pharmaceuticals Intl(KNSA) | ORD SHS CL A | G52694109 | $1.1M | 29,200 | 0.2% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $1.1M | 20,400 | 0.2% |
| Mereo Biopharma Group PLC(MREO) | SPON ADS | 589492107 | $979.2K | 475,361 | 0.2% |
| Sarepta Therapeutics Inc | COM | 830607100 | $865.2K | 44,900 | 0.1% |
| Sarepta Therapeutics Inc(SRPT)A | COM | 803607100 | $865.2K | 44,900 | 0.1% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $738.5K | 30,900 | 0.1% |
| Moderna Inc(MRNA) | COM | 60770K107 | $614.8K | 23,800 | 0.1% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $506.1K | 41,555 | 0.1% |
| Atyr Pharma Inc(ATYR)Call | COM NEW | 002120202 | $432.8K | 600,000 | 0.1% |