Q4 2025 Holdings
Filed 2026-02-17 | 270 holdings | $1.4B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2026-02-18) | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $177.6M | 1,317,329 | 13.0% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $91.6M | 1,049,168 | 6.7% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $74.4M | 3,428,962 | 5.5% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $63.1M | 2,480,968 | 4.6% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $39.4M | 546,534 | 2.9% |
| EA Series Trust(BOXX) | ALPHA ARCH 1-3 | 02072L565 | $38.8M | 337,125 | 2.8% |
| Spdr S&P 500 ETF TR(SPY) | TR UNIT | 78462F103 | $37.3M | 54,684 | 2.7% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $34.3M | 540,166 | 2.5% |
| Septerna Inc(SEPN) | COM | 81734D104 | $32.3M | 1,157,611 | 2.4% |
| Arbutus Biopharma Corp(ABUS) | COM | 03879J100 | $26.0M | 5,415,109 | 1.9% |
| ZAI LAB LTD(ZLAB) | ADR | 98887Q104 | $22.0M | 1,246,520 | 1.6% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $21.9M | 541,615 | 1.6% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $17.8M | 4,182,769 | 1.3% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $17.6M | 646,767 | 1.3% |
| Rapt Therapeutics Inc(RAPT) | COM NEW | 75382E208 | $17.3M | 509,679 | 1.3% |
| Inhibikase Therapeutics Inc(IKT) | COM NEW | 45719W205 | $16.5M | 8,063,949 | 1.2% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $16.3M | 213,414 | 1.2% |
| Monopar Therapeutics Inc(MNPR) | COM NEW | 61023L207 | $15.3M | 233,908 | 1.1% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $14.6M | 315,642 | 1.1% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $14.4M | 309,368 | 1.1% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $14.2M | 1,253,749 | 1.0% |
| Prothena Corp PLC(PRTA) | SHS | G72800108 | $13.9M | 1,457,764 | 1.0% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $13.8M | 1,393,161 | 1.0% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $13.7M | 2,495,809 | 1.0% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $13.2M | 59,677 | 1.0% |
| Inventiva SA(IVA) | ADS | 46124U107 | $12.6M | 2,709,846 | 0.9% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $12.5M | 171,422 | 0.9% |
| Spdr Series Trust(BIL) | STATE STREET SPD | 78468R663 | $12.4M | 135,585 | 0.9% |
| Replimune Group Inc(REPL) | COM | 76029N106 | $12.1M | 1,241,322 | 0.9% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $11.6M | 147,130 | 0.9% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $11.6M | 145,079 | 0.8% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $10.8M | 890,356 | 0.8% |
| CG Oncology Inc(CGON) | COM | 156944100 | $10.7M | 258,139 | 0.8% |
| Teleflex Incorporated(TFX) | COM | 879369106 | $9.8M | 80,627 | 0.7% |
| Invivyd Inc(IVVD) | COM | 00534A102 | $9.6M | 3,899,397 | 0.7% |
| Regeneron Pharmaceuticals(REGN) | COM | 75886F107 | $9.3M | 12,051 | 0.7% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $9.1M | 203,969 | 0.7% |
| Equillium Inc(EQ) | COM | 29446K106 | $8.7M | 5,608,078 | 0.6% |
| Savara Inc(SVRA) | COM | 805111101 | $8.5M | 1,405,452 | 0.6% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $7.4M | 179,532 | 0.5% |
| Teva Pharmaceutical Inds LTD(TEVA) | SPONSORED ADS | 881624209 | $7.4M | 235,971 | 0.5% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $7.2M | 606,000 | 0.5% |
| Ovid Therapeutics Inc(OVID) | COM | 690469101 | $7.0M | 4,285,000 | 0.5% |
| Ishares TR(IWM)Put | RUSSELL 2000 ETF | 464287655 | $6.8M | 27,500 | 0.5% |
| Belite BIO Inc(BLTE) | SPONSORED ADS | 07782B104 | $6.4M | 39,839 | 0.5% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $6.2M | 13,716 | 0.5% |
| Brighthouse Finl Inc(BHF) | COM | 10922N103 | $6.2M | 95,523 | 0.5% |
| Anteris Technologies Global(AVR) | COM | 03675P102 | $6.2M | 1,238,777 | 0.5% |
| AA Mission Acquisition Corp | ORD SHS CL A | G1000R101 | $6.2M | 578,359 | 0.5% |
| Protara Therapeutics Inc(TARA) | COM STK | 74365U107 | $6.1M | 1,136,799 | 0.4% |