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Siren, L.L.C.

Q1 2025 Holdings

Filed 2025-05-14 | 117 holdings | $1.8B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗

Amended (2025-05-23) | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↑Shares% Portfolio
Avidity Biosciences Inc(RNA)COM05370A108$32.8M1,110,6101.8%
Arrowhead Pharmaceuticals Inc(ARWR)COM04280A100$34.0M2,669,8801.9%
Edgewise Therapeutics Inc(EWTX)COM28036F105$37.3M1,696,4442.1%
NewAmsterdam Pharma Company NV(NAMS)ORDINARY SHARESN62509109$39.1M1,912,0302.2%
Centessa Pharmaceuticals PLC(CNTA)SPONSORED ADS152309100$42.6M2,960,0292.4%
Bicara Therapeutics Inc(BCAX)COM055477103$42.6M3,267,0832.4%
Merus NVCOMN5749R100$43.9M1,043,4672.5%
Ascendis Pharma A/S(ASND)SPONSORED ADR04351P101$44.8M287,3662.5%
Soleno Therapeutics Inc(SLNO)COM834203309$52.0M727,3372.9%
Disc Medicine Inc(IRON)COM254604101$53.2M1,071,8653.0%
Apellis Pharmaceuticals Inc(APLS)COM03753U106$56.4M2,578,3963.2%
Crinetics Pharmaceuticals Inc(CRNX)COM22663K107$56.6M1,688,6113.2%
Blueprint Medicines Corp(2L9)COM09627Y109$64.3M726,1673.6%
Kymera Therapeutics Inc(KYMR)COM501575104$88.7M3,240,3135.0%
Beigene Ltd(ONC)SPONSORED ADS07725L102$135.7M498,6897.7%
Scholar Rock Holding Corp(SRRK)COM80706P103$297.4M9,250,00516.8%
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