Q4 2025 Holdings
Filed 2026-02-17 | 41 holdings | $3.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $428.2M | 5,502,710 | 14.4% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $267.4M | 3,356,782 | 9.0% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $260.3M | 19,751,284 | 8.8% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $242.0M | 3,479,022 | 8.1% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $132.4M | 5,295,893 | 4.5% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $118.1M | 1,495,290 | 4.0% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $112.1M | 8,827,712 | 3.8% |
| Xencor Inc(XNCR) | COM | 98401F105 | $109.2M | 7,133,720 | 3.7% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $103.7M | 3,938,641 | 3.5% |
| Palvella Therapeutics Inc NE(PVLA) | COM | 697947109 | $92.0M | 879,009 | 3.1% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $89.5M | 8,617,162 | 3.0% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $71.9M | 2,265,674 | 2.4% |
| Xoma Royalty Corporation(XOMA) | COM NEW | 98419J206 | $68.9M | 2,590,303 | 2.3% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $68.5M | 508,031 | 2.3% |
| Nektar Therapeutics(NKTR) | COM NEW | 640268306 | $65.9M | 1,559,595 | 2.2% |
| AC Immune SA(ACIU) | SHS | H00263105 | $62.2M | 19,822,436 | 2.1% |
| Monte Rosa Therapeutics Inc(GLUE) | COM | 61225M102 | $60.1M | 3,835,886 | 2.0% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $59.5M | 5,750,683 | 2.0% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $55.9M | 2,127,665 | 1.9% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $51.6M | 650,000 | 1.7% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $50.3M | 1,488,975 | 1.7% |
| Invivyd Inc(IVVD) | COM | 00534A102 | $48.2M | 19,525,000 | 1.6% |
| Septerna Inc(SEPN) | COM | 81734D104 | $48.0M | 1,720,782 | 1.6% |
| Annexon Inc(ANNX) | COM | 03589W102 | $45.8M | 9,128,080 | 1.5% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $41.7M | 7,764,842 | 1.4% |
| 4D Molecular Therapeutics in(FDMT) | COM | 35104E100 | $34.7M | 4,629,289 | 1.2% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $32.6M | 2,748,763 | 1.1% |
| Foghorn Therapeutics Inc(FHTX) | COM | 344174107 | $28.6M | 5,302,000 | 1.0% |
| Repare Therapeutics Inc(RPTX) | COM | 760273102 | $26.9M | 10,333,600 | 0.9% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $24.6M | 1,355,257 | 0.8% |
| Pepgen Inc(PEPG) | COM | 713317105 | $12.5M | 1,915,000 | 0.4% |
| Eledon Pharmaceuticals Inc(ELDN) | COM | 28617K101 | $9.5M | 6,293,282 | 0.3% |
| X4 Pharmaceuticals Inc(XFOR) | COM NEW | 98420X202 | $8.9M | 2,233,742 | 0.3% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $8.4M | 45,757 | 0.3% |
| Molecular Partners AG(MOLN) | ADS | 60853G106 | $5.8M | 1,353,968 | 0.2% |
| Imagenebio Inc(IMA) | COM | 45175G207 | $5.5M | 802,102 | 0.2% |
| Tscan Therapeutics Inc(TCRX) | COM | 89854M101 | $5.2M | 5,226,074 | 0.2% |
| Tenax Therapeutics Inc(TENX) | COM NEW | 88032L605 | $4.1M | 339,549 | 0.1% |
| Immunic Inc(IMUX) | COM | 4525EP101 | $4.1M | 7,652,972 | 0.1% |
| Inventiva SA(IVA) | ADS | 46124U107 | $3.2M | 686,040 | 0.1% |
| Engene Holdings Inc(ENGNW) | *W EXP 10/31/202 | 29286M113 | $2.4M | 945,402 | 0.1% |