Q2 2026 Holdings
Filed 2026-08-14 | 109 holdings | $6.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $681.6M | 2,035,986 | 10.2% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $383.5M | 4,319,496 | 5.8% |
| Celcuity Inc(CELC) | COM | 15102K100 | $334.5M | 3,197,200 | 5.0% |
| Ascendis Pharma A/S(ASND) | ORD SHS | K08588103 | $310.4M | 1,163,721 | 4.7% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $287.2M | 2,586,295 | 4.3% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $286.1M | 8,085,461 | 4.3% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $263.9M | 14,106,187 | 4.0% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $213.2M | 3,752,574 | 3.2% |
| Kardigan Inc(KARD) | COM | 485925101 | $195.6M | 8,200,662 | 2.9% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $195.2M | 1,580,505 | 2.9% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $177.7M | 4,373,974 | 2.7% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $173.6M | 1,308,113 | 2.6% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $149.7M | 8,334,882 | 2.2% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $145.7M | 10,786,658 | 2.2% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $128.0M | 1,345,063 | 1.9% |
| Inhibrx Biosciences Inc(INBX) | COM | 45720N103 | $123.0M | 1,297,763 | 1.8% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $120.4M | 981,879 | 1.8% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $118.9M | 11,906,646 | 1.8% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $109.3M | 4,182,953 | 1.6% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $105.6M | 3,377,000 | 1.6% |
| Immatics N.v(IMTX) | SHS | N44445109 | $105.2M | 10,383,456 | 1.6% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $104.8M | 4,320,422 | 1.6% |
| Biocryst Pharmaceuticals Inc(BCRX) | COM | 09058V103 | $103.1M | 10,308,888 | 1.5% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $98.8M | 527,600 | 1.5% |
| Avalyn Pharmaceuticals Inc(AVLN) | COM SHS | 05348Y105 | $88.1M | 2,675,296 | 1.3% |
| Moderna Inc(MRNA)Put | COM | 60770K107 | $70.0M | 1,000,000 | 1.1% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $59.7M | 2,689,235 | 0.9% |
| Biogen Inc(BIIB) | COM | 09062X103 | $59.7M | 276,173 | 0.9% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $52.3M | 1,357,383 | 0.8% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $48.5M | 116,806 | 0.7% |
| Spdr Series Trust(XBI)Put | ST STR SP BIOT | 78464A870 | $47.5M | 300,000 | 0.7% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $44.9M | 566,000 | 0.7% |
| Sutro Biopharma Inc(STRO) | COM SHS | 869367201 | $43.3M | 1,304,846 | 0.7% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $42.5M | 1,609,893 | 0.6% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $41.0M | 170,000 | 0.6% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $39.9M | 2,667,441 | 0.6% |
| Sionna Therapeutics Inc(SION) | COM | 829401108 | $39.8M | 905,000 | 0.6% |
| Cytomx Therapeutics Inc.(CTMX) | COM | 23284F105 | $39.1M | 10,439,185 | 0.6% |
| Artivion Inc(AORT) | COM | 228903100 | $39.0M | 1,737,290 | 0.6% |
| X4 Pharmaceuticals Inc(XFOR) | COM NEW | 98420X202 | $37.0M | 7,933,491 | 0.6% |
| Corcept Therapeutics Inc(CORT) | COM | 218352102 | $34.6M | 398,385 | 0.5% |
| Repligen Corp(RGEN) | COM | 759916109 | $33.9M | 248,212 | 0.5% |
| Anteris Technologies Global(AVR) | COM | 03675P102 | $33.7M | 3,425,476 | 0.5% |
| Rapport Therapeutics Inc(RAPP) | COM | 75383L102 | $32.2M | 773,342 | 0.5% |
| Damora Therapeutics Inc(GLTO) | COM NEW | 36322Q206 | $31.8M | 1,223,000 | 0.5% |
| Charles RIV Labs Intl Inc(CRL) | COM | 159864107 | $31.8M | 140,000 | 0.5% |
| Axsome Therapeutics Inc.(AXSM) | COM | 05464T104 | $29.0M | 118,450 | 0.4% |
| Eyepoint Inc(EYPT)Put | COM NEW | 30233G209 | $28.6M | 2,000,000 | 0.4% |
| DBV Technologies S A(DBVT) | SPONSORED ADS | 23306J309 | $27.1M | 1,653,350 | 0.4% |
| Irhythm Holdings Inc(IRTC) | COM | 450056106 | $26.6M | 223,766 | 0.4% |