Q4 2022 Holdings
Filed 2023-02-14 | 70 holdings | $4.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $849.7M | 6,957,179 | 17.2% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $280.9M | 5,857,459 | 5.7% |
| Aerovate Therapeutics Inc | COM | 008064107 | $242.1M | 8,263,982 | 4.9% |
| Dice Therapeutics Inc | COM | 23345J104 | $213.7M | 6,848,911 | 4.3% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $165.1M | 6,317,990 | 3.3% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $160.6M | 5,516,067 | 3.3% |
| DAY One Biopharmaceuticals I(DAWN) | COM | 23954D109 | $151.5M | 7,040,622 | 3.1% |
| VOR Biopharma Inc | COM | 929033108 | $151.3M | 22,748,880 | 3.1% |
| Biogen Inc(BIIB) | COM | 09062X103 | $147.6M | 532,892 | 3.0% |
| Cytek Biosciences Inc(CTKB) | COM | 23285D109 | $136.6M | 13,381,054 | 2.8% |
| Legend Biotech Corp(LEGN) | SPONSORED ADS | 52490G102 | $121.6M | 2,436,223 | 2.5% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $121.0M | 5,454,533 | 2.5% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $120.4M | 17,202,009 | 2.4% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $114.2M | 8,670,644 | 2.3% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $114.0M | 8,955,410 | 2.3% |
| Pepgen Inc(PEPG) | COM | 713317105 | $108.7M | 8,131,952 | 2.2% |
| Immunogen Inc(IMGNEUR) | COM | 45253H101 | $108.4M | 21,853,958 | 2.2% |
| Bellus Health Inc New(BLU) | COM NEW | 07987C204 | $102.4M | 12,452,574 | 2.1% |
| Inhibrx Inc(INBXUSD) | COM | 45720L107 | $95.0M | 3,853,867 | 1.9% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $92.5M | 2,075,000 | 1.9% |
| Iteos Therapeutics Inc(5E7) | COM | 46565G104 | $86.3M | 4,417,259 | 1.7% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $83.8M | 3,984,681 | 1.7% |
| Cogent Communications Hldgs(COGT) | COM NEW | 19240Q201 | $69.4M | 5,999,481 | 1.4% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $69.3M | 4,398,453 | 1.4% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $69.2M | 9,505,925 | 1.4% |
| Acrivon Therapeutics Inc(ACRV) | COMMON STOCK | 004890109 | $55.4M | 4,810,508 | 1.1% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $55.0M | 7,236,454 | 1.1% |
| Acumen Pharmaceuticals Inc(ABOS) | COM | 00509G209 | $52.8M | 9,770,773 | 1.1% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $52.6M | 958,980 | 1.1% |
| Eliem Therapeutics Inc(CLYM) | COM | 28658R106 | $48.3M | 13,150,849 | 1.0% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $47.6M | 4,898,373 | 1.0% |
| Icosavax Inc | COM | 45114M109 | $47.4M | 5,963,565 | 1.0% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $47.1M | 2,407,149 | 1.0% |
| Nkarta Inc(NKTX) | COM | 65487U108 | $46.8M | 7,805,129 | 0.9% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $43.6M | 4,000,000 | 0.9% |
| Rxsight Inc(RXST) | COM | 78349D107 | $38.7M | 3,052,796 | 0.8% |
| An2 Therapeutics Inc(ANTX) | COM | 037326105 | $36.0M | 3,773,517 | 0.7% |
| Alpine Immune Sciences Inc(NVLSEUR) | COM | 02083G100 | $32.3M | 4,397,368 | 0.7% |
| Geron Corp(GERN) | COM | 374163103 | $31.3M | 12,930,711 | 0.6% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $30.5M | 2,971,231 | 0.6% |
| Hillevax Inc | COM | 43157M102 | $29.4M | 1,760,019 | 0.6% |
| Kinnate Biopharma Inc | COM | 49705R105 | $26.0M | 4,264,144 | 0.5% |
| Viridian Therapeutics Inc(VRDN) | SPONSORED ADS | 92790C104 | $25.7M | 880,000 | 0.5% |
| ARS Pharmaceuticals Inc(SPRY) | COM | 82835W108 | $25.7M | 3,009,678 | 0.5% |
| Celcuity Inc(CELC) | COM | 15102K100 | $19.6M | 1,400,001 | 0.4% |
| Solid Biosciences Inc(SLDB) | COM | 83422E204 | $18.4M | 3,426,286 | 0.4% |
| Da32 Life Scnce | CLASS A COM | 23312M106 | $15.0M | 1,500,000 | 0.3% |
| Scpharmaceuticals Inc(SCPH) | COM | 810648105 | $13.3M | 1,856,904 | 0.3% |
| Imara Inc | COM | 45249V107 | $13.3M | 3,250,724 | 0.3% |
| Tenaya Therapeutics Inc(TNYA) | COM | 87990A106 | $12.2M | 6,067,483 | 0.2% |