Q4 2025 Holdings
Filed 2026-02-13 | 60 holdings | $2.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Natera Inc(NTRA) | COM | 632307104 | $355.2M | 1,550,280 | 15.3% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $163.2M | 959,860 | 7.0% |
| Astrazeneca PLC(AZN) | SPONSORED ADR | 046353108 | $150.1M | 1,632,334 | 6.5% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $141.5M | 2,793,987 | 6.1% |
| Bristol-Myers Squibb Co(BMY) | COM | 110122108 | $81.6M | 1,512,994 | 3.5% |
| United Therapeutics Corp(UTHR) | COM | 91307C102 | $76.8M | 157,641 | 3.3% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $74.6M | 164,594 | 3.2% |
| Abbvie Inc(ABBV) | COM | 00287Y109 | $72.6M | 317,783 | 3.1% |
| Intuitive Surgical Inc(ISRG) | COM | 46120E602 | $71.9M | 126,968 | 3.1% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $70.1M | 1,973,625 | 3.0% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $66.3M | 61,652 | 2.9% |
| Rapport Therapeutics Inc(RAPP) | COM | 75383L102 | $57.8M | 1,904,408 | 2.5% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $55.1M | 720,448 | 2.4% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $53.7M | 745,116 | 2.3% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $44.1M | 2,254,161 | 1.9% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $41.4M | 697,133 | 1.8% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $40.4M | 534,845 | 1.7% |
| Cidara Therapeutics Inc(CDTX) | COM | 171757206 | $39.8M | 180,265 | 1.7% |
| Praxis Precision Medicines Inc(PRAX) | COM | 74006W207 | $37.1M | 125,722 | 1.6% |
| Immatics N.v(IMTX) | SHS | N44445109 | $36.1M | 3,435,542 | 1.6% |
| Inhibrx Biosciences Inc(INBX) | COM | 45720N103 | $35.9M | 454,657 | 1.5% |
| Immunome Inc(IMNM) | COM | 45257U108 | $34.8M | 1,618,477 | 1.5% |
| Arrivent Biopharma Inc(AVBP) | COM | 04272N102 | $34.1M | 1,696,752 | 1.5% |
| Glaukos Corp(GKOS) | COM | 377322102 | $32.5M | 288,128 | 1.4% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $30.6M | 885,121 | 1.3% |
| Bioage Labs Inc(BIOA) | COM | 09077V100 | $30.3M | 2,293,788 | 1.3% |
| Celcuity Inc(CELC) | COM | 15102K100 | $29.9M | 299,417 | 1.3% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $29.1M | 271,394 | 1.3% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $27.6M | 1,104,274 | 1.2% |
| Supernus Pharmaceuticals Inc(SUPN) | COM | 868459108 | $27.5M | 553,095 | 1.2% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $27.3M | 156,801 | 1.2% |
| Alcon AG(ALC) | ORD SHS | H01301128 | $26.2M | 332,520 | 1.1% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $26.1M | 1,096,705 | 1.1% |
| Dexcom Inc(DXCM) | COM | 252131107 | $25.1M | 378,219 | 1.1% |
| Pharvaris N V(PHVS) | COM | N69605108 | $20.7M | 745,169 | 0.9% |
| Nektar Therapeutics(NKTR) | COM | 640268306 | $18.5M | 438,630 | 0.8% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $18.1M | 3,365,446 | 0.8% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $15.9M | 734,582 | 0.7% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $13.9M | 287,690 | 0.6% |
| GE Healthcare Technologies I(GEHC) | COMMON STOCK | 36266G107 | $13.2M | 160,876 | 0.6% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $10.9M | 437,819 | 0.5% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $10.3M | 101,443 | 0.4% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $8.8M | 111,010 | 0.4% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $6.4M | 527,099 | 0.3% |
| Masimo Corp(MASI) | COM | 574795100 | $6.0M | 46,201 | 0.3% |
| Uniqure NV(QURE) | SHS | N90064101 | $4.2M | 176,513 | 0.2% |
| Nextcure Inc(NXTC) | COM | 65343E207 | $3.2M | 222,654 | 0.1% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $2.7M | 158,182 | 0.1% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $2.7M | 59,900 | 0.1% |
| Evommune Inc(EVMN) | COM SHS | 30054Y107 | $2.6M | 153,320 | 0.1% |