Q4 2024 Holdings
Filed 2025-02-14 | 119 holdings | $4.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $401.1M | 15,021,721 | 8.3% |
| Sinovac Biotech LTD(SVA) | SHS | P8696W104 | $334.0M | 2,718,735 | 6.9% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $282.3M | 3,160,300 | 5.8% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $260.6M | 337,600 | 5.4% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $209.7M | 401,700 | 4.3% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $179.1M | 7,959,538 | 3.7% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $128.1M | 938,120 | 2.6% |
| Stryker Corporation(SYK) | COM | 863667101 | $124.0M | 344,400 | 2.6% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $117.1M | 963,400 | 2.4% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $116.7M | 189,700 | 2.4% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $113.2M | 1,785,571 | 2.3% |
| Tenet Healthcare Corp(THC) | COM NEW | 88033G407 | $100.0M | 792,000 | 2.1% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $98.5M | 2,817,347 | 2.0% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $97.8M | 415,600 | 2.0% |
| Upstream BIO Inc(UPB) | COM | 91678A107 | $93.6M | 5,693,589 | 1.9% |
| ARS Pharmaceuticals Inc(SPRY) | COM | 82835W108 | $87.4M | 8,288,510 | 1.8% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $84.8M | 1,145,302 | 1.7% |
| Merck & Co Inc(MRK) | COM | 58933Y105 | $82.6M | 829,900 | 1.7% |
| Arrivent Biopharma Inc(AVBP) | COM | 04272N102 | $80.6M | 3,027,328 | 1.7% |
| Biogen Inc(BIIB) | COM | 09062X103 | $77.9M | 509,100 | 1.6% |
| Integer Hldgs Corp(ITGR) | COM | 45826H109 | $76.2M | 575,000 | 1.6% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $74.5M | 1,584,005 | 1.5% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $70.3M | 3,812,215 | 1.4% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $66.2M | 130,900 | 1.4% |
| Natera Inc(NTRA) | COM | 632307104 | $65.4M | 413,000 | 1.3% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $60.8M | 151,000 | 1.3% |
| Third Harmonic BIO Inc(THRD) | COM | 88427A107 | $59.5M | 5,779,071 | 1.2% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $51.1M | 999,000 | 1.1% |
| Universal Hlth Svcs Inc(UHS) | CL B | 913903100 | $48.3M | 269,300 | 1.0% |
| Si-Bone Inc(SIBN) | COM | 825704109 | $48.3M | 3,442,853 | 1.0% |
| Springworks Therapeutics Inc | COM | 85205L107 | $45.3M | 1,255,031 | 0.9% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $43.9M | 84,400 | 0.9% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $41.9M | 7,562,971 | 0.9% |
| CG Oncology Inc(CGON) | COM | 156944100 | $41.0M | 1,431,114 | 0.8% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $40.6M | 758,566 | 0.8% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $38.2M | 679,816 | 0.8% |
| Neuropace Inc(NPCE) | COM | 641288105 | $38.1M | 3,406,335 | 0.8% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $37.2M | 947,877 | 0.8% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $37.1M | 6,943,654 | 0.8% |
| Spdr SER TR(XBI) | S&P BIOTECH | 78464A870 | $33.5M | 372,000 | 0.7% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $32.4M | 22,362,850 | 0.7% |
| Xtant MED Hldgs Inc(XTNT) | COM NEW | 98420P308 | $32.4M | 73,114,592 | 0.7% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $32.4M | 1,112,886 | 0.7% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $31.4M | 742,572 | 0.6% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $28.9M | 1,227,080 | 0.6% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $23.7M | 1,942,555 | 0.5% |
| VIR Biotechnology Inc(VIR) | COM | 92764N102 | $23.6M | 3,218,617 | 0.5% |
| Gilead Sciences Inc(GILD) | COM | 375558103 | $22.7M | 245,600 | 0.5% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $22.4M | 400,000 | 0.5% |
| Immatics N.v(IMTX) | SHS | N44445109 | $22.0M | 3,087,462 | 0.5% |