Q3 2025 Holdings
Filed 2025-11-14 | 110 holdings | $4.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $251.7M | 15,518,492 | 5.9% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $237.2M | 2,429,300 | 5.6% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $229.8M | 301,200 | 5.4% |
| Sinovac Biotech LTD(SVA) | SHS | P8696W104 | $184.5M | 2,718,735 | 4.3% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $162.9M | 7,959,538 | 3.8% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $137.5M | 301,600 | 3.2% |
| Stryker Corporation(SYK) | COM | 863667101 | $132.8M | 359,200 | 3.1% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $131.0M | 1,684,000 | 3.1% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $128.4M | 287,200 | 3.0% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $127.1M | 172,300 | 3.0% |
| Sionna Therapeutics Inc(SION) | COM | 829401108 | $109.0M | 3,704,959 | 2.6% |
| Upstream BIO Inc(UPB) | COM | 91678A107 | $107.1M | 5,693,589 | 2.5% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $93.5M | 1,415,020 | 2.2% |
| Caris Life Sciences Inc(CAI) | COM | 142152107 | $91.8M | 3,034,858 | 2.2% |
| ARS Pharmaceuticals Inc(SPRY) | COM | 82835W108 | $83.3M | 8,288,510 | 2.0% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $71.4M | 1,638,886 | 1.7% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $70.1M | 4,002,887 | 1.6% |
| CG Oncology Inc(CGON) | COM | 156944100 | $69.6M | 1,726,850 | 1.6% |
| Natera Inc(NTRA) | COM | 632307104 | $69.1M | 429,300 | 1.6% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $64.6M | 531,800 | 1.5% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $56.8M | 7,562,971 | 1.3% |
| Arrivent Biopharma Inc(AVBP) | COM | 04272N102 | $55.9M | 3,027,328 | 1.3% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $55.7M | 1,469,494 | 1.3% |
| Exact Sciences Corp(EXAS) | COM | 30063P105 | $54.4M | 994,616 | 1.3% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $53.3M | 15,219,994 | 1.3% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $52.8M | 7,165,006 | 1.2% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $52.6M | 2,323,368 | 1.2% |
| Danaher Corporation(DHR) | COM | 235851102 | $52.2M | 263,100 | 1.2% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $49.6M | 353,640 | 1.2% |
| United Therapeutics Corp del(UTHR) | COM | 91307C102 | $48.2M | 114,900 | 1.1% |
| The Cigna Group(CI) | COM | 125523100 | $46.9M | 162,800 | 1.1% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $45.8M | 1,099,000 | 1.1% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $43.7M | 3,641,756 | 1.0% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $43.2M | 1,766,100 | 1.0% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $41.1M | 2,714,798 | 1.0% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $38.2M | 191,905 | 0.9% |
| Si-Bone Inc(SIBN) | COM | 825704109 | $38.0M | 2,578,979 | 0.9% |
| Scpharmaceuticals Inc(SCPH) | COM | 810648105 | $34.4M | 6,059,528 | 0.8% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $32.3M | 380,000 | 0.8% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $31.9M | 1,139,300 | 0.7% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $30.3M | 3,308,400 | 0.7% |
| Integer Hldgs Corp(ITGR) | COM | 45826H109 | $30.0M | 290,000 | 0.7% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $29.3M | 2,314,184 | 0.7% |
| Rapt Therapeutics Inc(RAPT) | COM NEW | 75382E208 | $28.0M | 1,086,618 | 0.7% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $27.0M | 8,461,500 | 0.6% |
| Neuropace Inc(NPCE) | COM | 641288105 | $27.0M | 2,614,184 | 0.6% |
| Uniqure NV(QURE) | SHS | N90064101 | $26.8M | 458,500 | 0.6% |
| Eyepoint Pharmaceuticals Inc(EYPT) | COM NEW | 30233G209 | $25.6M | 1,796,000 | 0.6% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $25.0M | 526,200 | 0.6% |
| ADC Therapeutics SA(ADCT) | SHS | H0036K147 | $23.6M | 5,907,351 | 0.6% |