Q4 2025 Holdings
Filed 2026-02-17 | 75 holdings | $2.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Aurinia Pharmaceuticals Inc(AUPH) | COM | 05156V102 | $180.7M | 11,329,500 | 8.9% |
| Galapagos NV(GLPG) | SPON ADR | 36315X101 | $128.2M | 3,921,219 | 6.3% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $113.9M | 1,500,000 | 5.6% |
| Celcuity Inc(CELC) | COM | 15102K100 | $104.7M | 1,050,000 | 5.2% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $97.6M | 1,236,027 | 4.8% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $97.3M | 1,188,624 | 4.8% |
| Kiniksa Pharmaceuticals Intl(KNSA) | ORD SHS CL A | G52694109 | $93.2M | 2,259,889 | 4.6% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $91.2M | 2,628,538 | 4.5% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $90.2M | 16,790,809 | 4.5% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $73.9M | 4,573,530 | 3.6% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $64.9M | 900,000 | 3.2% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $64.6M | 1,332,087 | 3.2% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $62.0M | 1,892,200 | 3.1% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $55.8M | 1,792,626 | 2.8% |
| Capricor Therapeutics Inc(CAPR) | COM NEW | 14070B309 | $49.1M | 1,700,000 | 2.4% |
| Biontech SE(BNTX) | SPONSORED ADS | 09075V102 | $44.7M | 470,000 | 2.2% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $38.0M | 481,437 | 1.9% |
| Vertex Pharmaceuticals Inc(VRTX) | COM | 92532F100 | $36.3M | 80,000 | 1.8% |
| Nuvation BIO Inc(NUVB) | COM CL A | 67080N101 | $34.6M | 3,857,457 | 1.7% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $26.7M | 700,000 | 1.3% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $25.4M | 2,814,000 | 1.3% |
| Nvidia Corporation(NVDA) | COM | 67066G104 | $23.8M | 127,788 | 1.2% |
| Precigen Inc(PGEN) | COM | 74017N105 | $23.5M | 5,617,500 | 1.2% |
| Spdr S&P 500 ETF TR(SPY) | TR UNIT | 78462F103 | $20.5M | 30,000 | 1.0% |
| Moderna Inc(MRNA) | COM | 60770K107 | $20.4M | 692,820 | 1.0% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $17.6M | 500,000 | 0.9% |
| Atea Pharmaceuticals Inc(AVIR) | COM | 04683R106 | $17.2M | 4,814,700 | 0.8% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $15.9M | 500,000 | 0.8% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $15.6M | 450,000 | 0.8% |
| Meta Platforms Inc(META) | CL A | 30303M102 | $15.4M | 23,331 | 0.8% |
| GSK PLC(GSK) | SPONSORED ADR | 37733W204 | $14.7M | 300,000 | 0.7% |
| Journey MED Corp(DERM) | COM | 48115J109 | $14.3M | 1,854,596 | 0.7% |
| Lenz Therapeutics Inc(LENZ) | COM | 52635N103 | $13.8M | 865,169 | 0.7% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $12.7M | 275,000 | 0.6% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $10.9M | 264,692 | 0.5% |
| Harmony Biosciences Hldgs in(HRMY) | COM | 413197104 | $10.9M | 290,292 | 0.5% |
| Bristol-Myers Squibb Co(BMY) | COM | 110122108 | $10.8M | 200,000 | 0.5% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $10.4M | 60,000 | 0.5% |
| Crescent Biopharma Inc.(CBIO) | COM | G2545C104 | $10.3M | 872,398 | 0.5% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $10.2M | 600,000 | 0.5% |
| Teladoc Health Inc(TDOC) | COM | 87918A105 | $9.8M | 1,400,000 | 0.5% |
| Dynavax Technologies Corp(DVAX) | COM NEW | 268158201 | $8.6M | 556,359 | 0.4% |
| Evolus Inc(EOLS) | COM | 30052C107 | $8.3M | 1,245,692 | 0.4% |
| Verastem Inc(VSTM) | COM NEW | 92337C203 | $8.3M | 1,069,810 | 0.4% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $8.2M | 350,000 | 0.4% |
| Heron Therapeutics Inc(HRTX) | COM | 427746102 | $8.1M | 6,250,000 | 0.4% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $8.0M | 300,000 | 0.4% |
| Altimmune Inc(ALT) | COM NEW | 02155H200 | $7.7M | 2,131,307 | 0.4% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $7.5M | 349,220 | 0.4% |
| Pliant Therapeutics Inc(PLRX) | COM | 729139105 | $7.5M | 6,143,132 | 0.4% |