Q4 2025 Holdings
Filed 2026-02-17 | 49 holdings | $718.4M | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Insmed Inc(INSM) | COM | 457669307 | $85.2M | 489,482 | 11.9% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $74.1M | 5,205,767 | 10.3% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $68.7M | 903,916 | 9.6% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $66.3M | 2,484,031 | 9.2% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $44.3M | 746,256 | 6.2% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $33.5M | 690,032 | 4.7% |
| Biogen Inc(BIIB) | SPONSORED ADS | 09062X103 | $32.3M | 183,571 | 4.5% |
| Dyne Therapeutics Inc(DYN) | SPONSORED ADS | 26818M108 | $28.8M | 1,472,197 | 4.0% |
| United Therapeutics Corp(UTHR) | COM | 91307C102 | $28.4M | 58,186 | 3.9% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $25.2M | 317,456 | 3.5% |
| Iovance Biotherapeutics Inc(IOVA) | COM NEW | 462260100 | $19.4M | 7,116,676 | 2.7% |
| Novocure LTD(NVCR) | COM | G6674U108 | $16.8M | 1,298,964 | 2.3% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $16.7M | 794,507 | 2.3% |
| Gossamer BIO Inc(GOSS) | COM | 38341P102 | $13.9M | 4,471,592 | 1.9% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $13.6M | 2,532,419 | 1.9% |
| Prothena Corp PLC(PRTA) | COM CL A | G72800108 | $12.6M | 1,320,510 | 1.8% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $12.4M | 156,421 | 1.7% |
| Annexon Inc(ANNX) | COM | 03589W102 | $12.0M | 2,384,192 | 1.7% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $10.6M | 461,294 | 1.5% |
| Denali Therapeutics Inc(DNLI) | COM | 24823R105 | $10.6M | 641,239 | 1.5% |
| Caredx Inc(CDNA) | COM | 14167L103 | $9.0M | 478,220 | 1.3% |
| Ehealth Inc(EHTH) | COM | 28238P109 | $7.0M | 1,531,429 | 1.0% |
| Alkermes PLC(ALKS) | COM | G01767105 | $6.8M | 242,560 | 0.9% |
| Capricor Therapeutics Inc(CAPR) | COM NEW | 14070B309 | $6.5M | 226,304 | 0.9% |
| Taysha Gene Therapies Inc(TSHA) | COM | 877619106 | $6.5M | 1,183,195 | 0.9% |
| Align Technology Inc(ALGN) | COM | 016255101 | $6.5M | 41,520 | 0.9% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $5.8M | 212,499 | 0.8% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $5.0M | 298,575 | 0.7% |
| Nuvation BIO Inc(NUVB) | COM CL A | 67080N101 | $4.8M | 538,079 | 0.7% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $4.7M | 1,566,840 | 0.7% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $4.3M | 96,519 | 0.6% |
| Travere Therapeutics Inc(TVTX) | COM SHS | 89422G107 | $4.2M | 110,719 | 0.6% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $2.9M | 33,640 | 0.4% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $2.6M | 18,117 | 0.4% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $2.3M | 72,022 | 0.3% |
| Crispr Therapeutics AG(CRSP) | NAMEN AKT | H17182108 | $2.2M | 41,226 | 0.3% |
| Biontech SE(BNTX) | COM | 09075V102 | $1.9M | 19,614 | 0.3% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $1.8M | 59,985 | 0.3% |
| Bicycle Therapeutics PLC(BCYC) | COM | 088786108 | $1.6M | 221,071 | 0.2% |
| Pyxis Oncology Inc(PYXS) | COM | 747324101 | $1.2M | 1,037,421 | 0.2% |
| Aldeyra Therapeutics Inc(ALDX) | SPONSORED ADR | 01438T106 | $1.2M | 225,465 | 0.2% |
| Humana Inc(HUM) | COM | 444859102 | $1.0M | 3,985 | 0.1% |
| Inspire Medical Systems Inc(INSP) | COM | 457730109 | $809.0K | 8,772 | 0.1% |
| Compass Pathways PLC ADR(CMPS) | SPONSORED ADS | 20451W101 | $797.8K | 115,616 | 0.1% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $573.8K | 24,500 | 0.1% |
| Abeona Therapeutics Inc(ABEO) | COM NEW | 00289Y206 | $573.7K | 108,865 | 0.1% |
| Proqr Therapeutics NV | SHS EURO | N71542109 | $381.4K | 188,807 | 0.1% |
| Generation BIO Co | COM | 37148K209 | $85.5K | 15,047 | 0.0% |
| Akari Therapeutics PLC(AKTX) | COM | 00972G207 | $42.2K | 146,024 | 0.0% |