Q4 2025 Holdings
Filed 2026-02-12 | 68 holdings | $720.1M | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $56.9M | 422,193 | 7.9% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $44.2M | 1,245,254 | 6.1% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $40.7M | 1,738,821 | 5.7% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $39.2M | 2,427,118 | 5.4% |
| Celcuity Inc(CELC) | COM | 15102K100 | $37.4M | 375,132 | 5.2% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $31.3M | 311,430 | 4.4% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $30.9M | 750,136 | 4.3% |
| Kodiak Sciences Inc(KOD) | COM | 50015M109 | $28.6M | 1,023,122 | 4.0% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $24.3M | 82,465 | 3.4% |
| Immunome Inc(IMNM) | COM | 45257U108 | $24.2M | 1,126,210 | 3.4% |
| Fractyl Health Inc(GUTS) | COM | 35168W103 | $21.6M | 9,840,041 | 3.0% |
| Uniqure NVCall | CALL | N90064901 | $17.2M | 720,800 | 2.4% |
| Monte Rosa Therapeutics Inc(GLUE) | COM | 61225M102 | $16.1M | 1,029,066 | 2.2% |
| Veracyte Inc(VCYT) | COM | 92337F107 | $15.1M | 357,558 | 2.1% |
| CG Oncology Inc(CGON) | COM | 156944100 | $15.0M | 361,158 | 2.1% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $14.6M | 135,950 | 2.0% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $13.5M | 642,899 | 1.9% |
| Biogen Inc(BIIB) | COM | 09062X103 | $13.3M | 75,412 | 1.8% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $12.4M | 71,256 | 1.7% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $11.5M | 458,203 | 1.6% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $10.8M | 348,569 | 1.5% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $10.5M | 49,228 | 1.5% |
| Pfizer Inc(PFE) | COM | 717081103 | $10.4M | 419,134 | 1.4% |
| Benitec Biopharma Inc(BNTC) | COM NEW | 08205P209 | $9.9M | 731,717 | 1.4% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $9.5M | 524,436 | 1.3% |
| Guardant Health Inc(GH) | COM | 40131M109 | $9.4M | 91,914 | 1.3% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $9.1M | 1,116,604 | 1.3% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $6.9M | 148,787 | 1.0% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $6.8M | 541,240 | 0.9% |
| Gossamer BIO Inc(GOSS) | COM | 38341P102 | $6.6M | 2,135,722 | 0.9% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $6.2M | 187,737 | 0.9% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $6.1M | 617,608 | 0.9% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $6.1M | 506,242 | 0.8% |
| Cerus Corp(CERS) | COM | 157085101 | $5.8M | 2,814,383 | 0.8% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $5.6M | 1,051,343 | 0.8% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $5.4M | 117,485 | 0.8% |
| Compugen LTD(CGEN) | ORD | M25722105 | $5.3M | 3,479,805 | 0.7% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $5.2M | 191,074 | 0.7% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $5.2M | 206,280 | 0.7% |
| Erasca Inc(ERAS) | COM | 29479A108 | $4.9M | 1,317,584 | 0.7% |
| Kalvista Pharmaceuticals IncCall | CALL | 483497903 | $4.7M | 290,600 | 0.7% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $4.5M | 394,650 | 0.6% |
| Fulcrum Therapeutics IncCall | CALL | 359616909 | $4.4M | 391,900 | 0.6% |
| Aardvark Therapeutics Inc(AARD) | COM | 002942100 | $4.0M | 303,939 | 0.6% |
| C4 Therapeutics Inc(CCCC) | COM STK | 12529R107 | $3.8M | 1,994,224 | 0.5% |
| Surrozen Inc(SRZN) | COM NEW | 86889P208 | $3.6M | 157,323 | 0.5% |
| Contineum Therapeutics Inc(CTNM) | CL A | 21217B100 | $3.5M | 307,540 | 0.5% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $3.4M | 94,983 | 0.5% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $3.4M | 398,167 | 0.5% |
| Abeona Therapeutics Inc(ABEO) | COM NEW | 00289Y206 | $3.3M | 627,738 | 0.5% |