Q4 2025 Holdings
Filed 2026-02-18 | 174 holdings | $1.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr Series Trust(XBI)Put | STATE STREET SPD | 78464A870 | $103.6M | 850,000 | 8.1% |
| Cidara Therapeutics Inc(CDTX)Put | COM NEW | 171757206 | $66.3M | 300,000 | 5.2% |
| Amgen Inc(AMGN)Put | COM | 031162100 | $65.5M | 200,000 | 5.1% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $64.5M | 1,596,378 | 5.0% |
| Cidara Therapeutics Inc(CDTX) | COM NEW | 171757206 | $60.4M | 273,243 | 4.7% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $29.1M | 205,985 | 2.3% |
| Jazz Pharmaceuticals PLC(JAZZ)Call | CALL | G50871905 | $28.9M | 170,000 | 2.3% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $27.3M | 160,367 | 2.1% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $26.7M | 644,680 | 2.1% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $25.5M | 86,581 | 2.0% |
| Harrow Inc(HROW)Call | COM | 415858109 | $25.0M | 509,700 | 1.9% |
| Soleno Therapeutics Inc(SLNO)Call | COM | 834203309 | $24.5M | 528,900 | 1.9% |
| Rapt Therapeutics Inc(RAPT) | COM NEW | 75382E208 | $22.5M | 665,271 | 1.8% |
| Kodiak Sciences Inc(KOD) | COM | 50015M109 | $20.1M | 719,787 | 1.6% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $19.0M | 758,654 | 1.5% |
| Cytokinetics Inc(CYTK)Call | COM NEW | 23282W605 | $18.5M | 290,900 | 1.4% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $17.5M | 378,682 | 1.4% |
| Crinetics Pharmaceuticals in(CRNX)Put | COM | 22663K107 | $17.2M | 368,500 | 1.3% |
| Abivax SA(ABVX)Call | SPONSORED ADS | 00370M103 | $16.9M | 125,100 | 1.3% |
| Capricor Therapeutics Inc(CAPR) | COM NEW | 14070B309 | $16.7M | 578,015 | 1.3% |
| Omeros Corp(OMER)Put | COM | 682143102 | $16.3M | 950,000 | 1.3% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $16.0M | 202,038 | 1.2% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $15.6M | 1,375,472 | 1.2% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $14.8M | 13,815 | 1.2% |
| Relmada Therapeutics Inc(RLMD) | COM | 75955J402 | $14.8M | 3,068,359 | 1.2% |
| Amgen Inc(AMGN) | COM | 031162100 | $14.7M | 45,000 | 1.1% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $13.5M | 3,172,616 | 1.1% |
| Pharvaris N V(PHVS) | COM | N69605108 | $13.5M | 486,856 | 1.1% |
| Connect Biopharma Hldgs LTD(CNTB) | SHS | G23549101 | $13.5M | 4,788,486 | 1.1% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $12.4M | 159,421 | 1.0% |
| Tenax Therapeutics Inc(TENX) | COM NEW | 88032L605 | $11.8M | 967,600 | 0.9% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $11.0M | 138,142 | 0.9% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $11.0M | 172,672 | 0.9% |
| Spruce Biosciences Inc(SPRB) | COM NEW | 85209E208 | $10.6M | 121,356 | 0.8% |
| Celcuity Inc(CELC) | COM | 15102K100 | $10.5M | 105,545 | 0.8% |
| Rapt Therapeutics Inc(RAPT)Call | COM NEW | 75382E208 | $9.8M | 290,000 | 0.8% |
| Omeros Corp(OMER)Call | COM | 682143102 | $9.4M | 550,000 | 0.7% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $9.2M | 515,000 | 0.7% |
| Dexcom Inc(DXCM)Call | COM | 252131107 | $9.1M | 137,500 | 0.7% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $9.0M | 118,657 | 0.7% |
| Harrow Inc(HROW) | COM | 415858109 | $9.0M | 183,347 | 0.7% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $8.7M | 958,704 | 0.7% |
| CG Oncology Inc(CGON) | COM | 156944100 | $8.3M | 199,473 | 0.6% |
| Corcept Therapeutics Inc(CORT)Put | COM | 218352102 | $8.2M | 236,700 | 0.6% |
| Forte Biosciences Inc(FBRX) | COM NEW | 34962G208 | $8.2M | 300,000 | 0.6% |
| Apellis Pharmaceuticals Inc(APLS)Call | COM | 03753U106 | $8.2M | 325,600 | 0.6% |
| Pelthos Therapeutics Inc(PTHS) | COM SHS | 171126204 | $7.9M | 255,758 | 0.6% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $7.7M | 54,062 | 0.6% |
| Revolution Medicines Inc(RVMD)Call | COM | 76155X100 | $7.6M | 95,000 | 0.6% |
| Ionis Pharmaceuticals Inc(IONS)Call | COM | 462222100 | $7.5M | 94,600 | 0.6% |