Q1 2023 Holdings
Filed 2023-05-15 | 60 holdings | $4.8B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Prometheus Biosciences Inc | COM | 74349U108 | $351.2M | 3,272,104 | 7.3% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $343.6M | 7,093,298 | 7.2% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $337.2M | 1,683,362 | 7.0% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $303.0M | 17,687,772 | 6.3% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $279.3M | 5,649,943 | 5.8% |
| Masimo Corp(MASI) | COM | 574795100 | $277.1M | 1,501,493 | 5.8% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $233.2M | 3,780,855 | 4.9% |
| Penumbra Inc(PEN) | COM | 70975L107 | $187.7M | 673,371 | 3.9% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $179.7M | 482,195 | 3.7% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $171.3M | 4,270,996 | 3.6% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $167.3M | 290,334 | 3.5% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $161.8M | 2,389,138 | 3.4% |
| Acadia Pharmaceuticals Inc C(ACAD) | COM | 004225108 | $155.1M | 8,242,864 | 3.2% |
| Natera Inc(NTRA) | COM | 632307104 | $145.0M | 2,611,783 | 3.0% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $135.5M | 3,643,114 | 2.8% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $111.0M | 3,084,215 | 2.3% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $105.8M | 4,600,799 | 2.2% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $100.2M | 5,118,507 | 2.1% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $98.0M | 6,387,178 | 2.0% |
| Vericel Corp(VCEL) | COM | 92346J108 | $96.5M | 3,291,873 | 2.0% |
| Bruker Corp(BRKR) | COM | 116794108 | $93.6M | 1,187,342 | 1.9% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $90.6M | 2,574,198 | 1.9% |
| Illumina Inc(ILMN) | COM | 452327109 | $87.5M | 376,250 | 1.8% |
| Avadel Pharmaceuticals PLC | SPONSORED ADR | 05337M104 | $52.6M | 5,741,939 | 1.1% |
| 10X Genomics Inc(TXG) | CL A COM | 88025U109 | $51.8M | 929,286 | 1.1% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $48.3M | 884,974 | 1.0% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $46.5M | 1,388,881 | 1.0% |
| Cutera Inc(CUTREUR) | COM | 232109108 | $43.6M | 1,846,596 | 0.9% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $36.6M | 4,390,558 | 0.8% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $32.0M | 2,548,125 | 0.7% |
| Scpharmaceuticals Inc(SCPH) | COM | 810648105 | $29.9M | 3,297,843 | 0.6% |
| Adicet BIO Inc(TORCEUR) | COM | 007002108 | $24.4M | 4,241,472 | 0.5% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $17.3M | 2,168,957 | 0.4% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $16.7M | 1,000,000 | 0.3% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $15.7M | 5,511,839 | 0.3% |
| Outset MED Inc(OMGBP) | COM | 690145107 | $14.9M | 808,658 | 0.3% |
| Olink Hldg AB | SPONSORED ADS | 680710100 | $14.7M | 654,612 | 0.3% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $14.4M | 922,100 | 0.3% |
| PMV Pharmaceuticals Inc(PMVP) | COM | 69353Y103 | $14.3M | 2,999,098 | 0.3% |
| Milestone Pharmaceuticals in(MIST) | COM | 59935V107 | $12.8M | 3,256,102 | 0.3% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $11.5M | 1,552,717 | 0.2% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $10.7M | 500,000 | 0.2% |
| Guardant Health Inc(GH) | COM | 40131M109 | $10.1M | 430,887 | 0.2% |
| Dermtech Inc(DMTKQ) | COM | 24984K105 | $10.0M | 2,718,356 | 0.2% |
| Apyx Medical Corporation(APYX) | COM | 03837C106 | $9.8M | 3,398,279 | 0.2% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $7.9M | 857,464 | 0.2% |
| Immunic Inc(IMUX) | COM | 4525EP101 | $6.4M | 4,294,459 | 0.1% |
| Allakos Inc(ALLKGUSD) | COM | 01671P100 | $5.9M | 1,326,608 | 0.1% |
| Castle Biosciences Inc(CSTL) | COM | 14843C105 | $5.9M | 258,498 | 0.1% |
| Immatics N.v(IMTX) | SHS | N44445109 | $5.8M | 845,000 | 0.1% |