Q2 2023 Holdings
Filed 2023-08-14 | 62 holdings | $5.3B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $361.5M | 6,029,633 | 6.9% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $351.5M | 17,687,772 | 6.7% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $319.7M | 1,683,362 | 6.1% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $307.9M | 4,284,277 | 5.9% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $294.3M | 7,235,196 | 5.6% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $249.3M | 5,405,089 | 4.7% |
| Masimo Corp(MASI) | COM | 574795100 | $247.1M | 1,501,493 | 4.7% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $234.3M | 9,783,249 | 4.5% |
| Penumbra Inc(PEN) | COM | 70975L107 | $231.7M | 673,371 | 4.4% |
| Bruker Corp(BRKR) | COM | 116794108 | $218.8M | 2,959,603 | 4.2% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $187.9M | 482,195 | 3.6% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $171.1M | 2,494,138 | 3.3% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $161.6M | 4,472,985 | 3.1% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $151.5M | 290,334 | 2.9% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $149.6M | 5,415,514 | 2.8% |
| Natera Inc(NTRA) | COM | 632307104 | $127.1M | 2,611,783 | 2.4% |
| Vericel Corp(VCEL) | COM | 92346J108 | $123.7M | 3,291,873 | 2.4% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $117.5M | 3,463,201 | 2.2% |
| Avadel Pharmaceuticals PLC | SPONSORED ADR | 05337M104 | $112.2M | 6,810,641 | 2.1% |
| Horizon Therapeutics PUB L | SHS | G46188101 | $102.9M | 1,000,000 | 2.0% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $84.0M | 2,574,198 | 1.6% |
| 10X Genomics Inc(TXG) | CL A COM | 88025U109 | $81.7M | 1,462,956 | 1.6% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $74.2M | 6,689,789 | 1.4% |
| Illumina Inc(ILMN) | COM | 452327109 | $70.5M | 376,250 | 1.3% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $58.1M | 170,000 | 1.1% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $51.2M | 221,562 | 1.0% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $46.7M | 4,390,558 | 0.9% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $46.0M | 2,548,125 | 0.9% |
| Axonics Inc(AXNX*) | COM | 05465P101 | $44.7M | 884,974 | 0.9% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $39.3M | 5,620,640 | 0.7% |
| Scpharmaceuticals Inc(SCPH) | COM | 810648105 | $33.6M | 3,297,843 | 0.6% |
| Cutera Inc(CUTREUR) | COM | 232109108 | $27.9M | 1,846,596 | 0.5% |
| Merus N V | COM | N5749R100 | $27.7M | 1,050,893 | 0.5% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $25.7M | 2,168,957 | 0.5% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $25.5M | 500,000 | 0.5% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $21.1M | 1,000,000 | 0.4% |
| Acelyrin Inc | COM | 00445A100 | $20.4M | 978,310 | 0.4% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $20.0M | 6,064,123 | 0.4% |
| Maravai Lifesciences Hldgs I(MRVI) | COM CL A | 56600D107 | $19.1M | 1,532,685 | 0.4% |
| PMV Pharmaceuticals Inc(PMVP) | COM | 69353Y103 | $19.0M | 3,029,551 | 0.4% |
| Guardant Health Inc(GH) | COM | 40131M109 | $17.9M | 500,887 | 0.3% |
| Outset MED Inc(OMGBP) | COM | 690145107 | $17.7M | 808,658 | 0.3% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $16.2M | 1,000,000 | 0.3% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $15.7M | 922,100 | 0.3% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $15.7M | 1,552,717 | 0.3% |
| Olink Hldg AB | SPONSORED ADS | 680710100 | $12.3M | 654,612 | 0.2% |
| Immunic Inc(IMUX) | COM | 4525EP101 | $10.8M | 4,294,459 | 0.2% |
| Adicet BIO Inc(TORCEUR) | COM | 007002108 | $10.3M | 4,241,472 | 0.2% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $9.8M | 1,563,031 | 0.2% |
| Immatics N.v(IMTX) | SHS | N44445109 | $9.8M | 845,000 | 0.2% |