Q4 2025 Holdings
Filed 2026-02-17 | 54 holdings | $757.9M | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2026-04-13) | View on SEC ↗ · Holdings Table ↗
Sign in to see sub-manager breakdown
| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Harrow Health Inc(HROW) | COM | 415858109 | $191.3M | 3,905,000 | 25.2% |
| Liquidia Corporation(LQDA) | COM NEW | 53635D202 | $85.0M | 2,435,000 | 11.2% |
| Eton Pharmaceuticals Inc(ETON) | COM | 29772L108 | $48.4M | 2,860,000 | 6.4% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $35.3M | 330,000 | 4.7% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $29.3M | 388,257 | 3.9% |
| Sanuwave Health Inc(SNWV) | COM | 80303D305 | $29.3M | 981,267 | 3.9% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $22.1M | 695,000 | 2.9% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $19.4M | 1,595,000 | 2.6% |
| SOL GEL Technologies(SLGL) | SHS NEW | M8694L137 | $19.1M | 453,739 | 2.5% |
| CG Oncology Inc(CGON) | COM | 156944100 | $17.0M | 410,000 | 2.2% |
| TG Therapeutics Inc(TGTX) | COM | 88322Q108 | $15.9M | 535,000 | 2.1% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $15.9M | 200,000 | 2.1% |
| Rezolute Inc(RZLT) | COM NEW | 76200L309 | $14.8M | 6,287,156 | 2.0% |
| Crescent Biopharma Inc(CBIO) | COM | G2545C104 | $14.0M | 1,178,300 | 1.8% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $13.7M | 490,000 | 1.8% |
| Alpha Cognition Inc(ACOG) | COM NEW | 02074J501 | $13.5M | 2,070,784 | 1.8% |
| Annexon Inc(ANNX) | COM | 03589W102 | $13.1M | 2,600,000 | 1.7% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $12.4M | 500,000 | 1.6% |
| Codexis Inc(CDXS) | COM | 192005106 | $11.1M | 6,789,738 | 1.5% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $9.2M | 105,000 | 1.2% |
| Gossamer BIO Inc(GOSS) | COM | 38341P102 | $8.4M | 2,720,000 | 1.1% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $8.2M | 260,000 | 1.1% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $8.0M | 100,000 | 1.1% |
| Xoma Corp del(XOMA) | COM NEW | 98419J206 | $7.8M | 292,590 | 1.0% |
| Journey Medical Corp(DERM) | COM | 48115J109 | $7.5M | 975,000 | 1.0% |
| Karyopharm Therapeutics Inc(KPTI) | COM NEW | 48576U205 | $6.8M | 930,000 | 0.9% |
| Jade Biosciences Inc(JBIO) | COM NEW | 008064206 | $6.6M | 427,608 | 0.9% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $6.3M | 268,423 | 0.8% |
| Alumis Inc(ALMS) | COM | 022307102 | $5.2M | 535,000 | 0.7% |
| Perspective Therapeutics Inc(CATX) | COM | 46489V302 | $5.0M | 1,184,500 | 0.7% |
| Voyager Therapeutics Inc(VYGR) | COM | 92915B106 | $4.7M | 1,196,904 | 0.6% |
| Relmada Therapeutics Inc(RLMD) | COM | 75955J402 | $4.5M | 935,000 | 0.6% |
| Tectonic Therapeutics Inc(TECX) | COM | 878972108 | $4.5M | 214,747 | 0.6% |
| Protalix Biotherapeutics Inc(PLX) | COM | 74365A309 | $4.5M | 2,478,176 | 0.6% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $4.3M | 345,100 | 0.6% |
| Fortress Biotech Inc(FBIO) | COM NEW | 34960Q307 | $4.0M | 1,090,000 | 0.5% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $3.4M | 955,000 | 0.4% |
| Meiragtx Holdings PLC(MGTX) | COM | G59665102 | $3.1M | 390,844 | 0.4% |
| Rigel Pharmaceuticals Inc(RIGL) | COM | 766559702 | $3.0M | 70,000 | 0.4% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $2.9M | 108,929 | 0.4% |
| Assertio Holdings Inc | COM NEW | 04546C205 | $2.6M | 285,000 | 0.3% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $2.3M | 251,932 | 0.3% |
| Opus Genetics Inc(IRD) | COM | 67577R102 | $2.3M | 1,120,000 | 0.3% |
| Sutro Biopharma Inc(STRO) | COM SHS | 869367201 | $2.2M | 190,671 | 0.3% |
| Cabaletta BIO Inc(CABA) | COM | 12674W109 | $2.0M | 900,000 | 0.3% |
| Zentalis Pharmaceuticals Inc(ZNTL) | COM | 98943L107 | $1.9M | 1,400,906 | 0.2% |
| Generation BIO Co | COM NEW | 37148K209 | $1.8M | 310,000 | 0.2% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $1.4M | 18,319 | 0.2% |
| Enanta Pharmaceuticals Inc(ENTA) | COM | 29251M106 | $1.2M | 75,000 | 0.2% |
| Q32 BIO Inc(QTTB) | COM | 746964105 | $708.4K | 213,363 | 0.1% |