Q4 2025 Holdings
Filed 2026-02-17 | 35 holdings | $2.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $280.0M | 950,000 | 12.9% |
| Bridgebio Oncology Therapeut(BBOT) | COM NEW | 107924102 | $223.8M | 17,878,594 | 10.4% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $182.1M | 1,350,000 | 8.4% |
| Invesco QQQ TR(QQQ)Put | UNIT SER 1 | 46090E103 | $153.6M | 250,000 | 7.1% |
| Eyepoint Inc(EYPT) | COM NEW | 30233G209 | $151.0M | 8,265,000 | 7.0% |
| Ishares TR(IWM)Put | RUSSELL 2000 ETF | 464287655 | $123.1M | 500,000 | 5.7% |
| Spdr Series Trust(XBI)Put | STATE STREET SPD | 78464A870 | $121.9M | 1,000,000 | 5.6% |
| Rapport Therapeutics Inc(RAPP) | COM | 75383L102 | $91.9M | 3,027,521 | 4.2% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $91.8M | 1,200,000 | 4.2% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $82.7M | 1,059,331 | 3.8% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $81.5M | 3,285,000 | 3.8% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $68.8M | 2,750,000 | 3.2% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $57.4M | 4,355,433 | 2.7% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $47.9M | 275,000 | 2.2% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $36.1M | 4,000,000 | 1.7% |
| Alumis Inc(ALMS) | COM | 022307102 | $35.5M | 3,635,596 | 1.6% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $35.3M | 1,120,000 | 1.6% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $35.1M | 1,000,000 | 1.6% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $33.1M | 1,325,000 | 1.5% |
| Pharvaris N V(PHVS) | COM | N69605108 | $30.1M | 1,083,000 | 1.4% |
| Bioage Labs Inc(BIOA) | COM | 09077V100 | $27.0M | 2,040,605 | 1.2% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $21.3M | 100,000 | 1.0% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $20.5M | 250,000 | 0.9% |
| Corbus Pharmaceuticals Hldgs(CRBP) | COM NEW | 21833P301 | $19.1M | 2,344,971 | 0.9% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $16.5M | 1,300,000 | 0.8% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $16.2M | 533,340 | 0.7% |
| Arcutis Biotherapeutics Inc(ARQT) | COM | 03969K108 | $14.5M | 500,000 | 0.7% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $14.0M | 300,000 | 0.6% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $13.7M | 75,000 | 0.6% |
| Cabaletta BIO Inc(CABA) | COM | 12674W109 | $9.6M | 4,400,000 | 0.4% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $9.0M | 650,000 | 0.4% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $8.0M | 225,000 | 0.4% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $5.8M | 125,000 | 0.3% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $4.8M | 400,000 | 0.2% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $112.9K | 10,000 | 0.0% |