Q4 2024 Holdings
Filed 2025-02-14 | 81 holdings | $1.6B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr SER TR(XBI)Call | S&P BIOTECH | 78464A870 | $270.2M | 3,000,000 | 17.0% |
| Novocure LTD(NVCR) | ORD SHS | G6674U108 | $81.6M | 2,739,704 | 5.1% |
| TG Therapeutics Inc(TGTX) | COM | 88322Q108 | $80.7M | 2,681,242 | 5.1% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $65.8M | 1,001,400 | 4.1% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $56.1M | 358,379 | 3.5% |
| Grifols S A(GRFS) | SP ADR REP B NVT | 398438408 | $49.1M | 6,605,425 | 3.1% |
| Axogen Inc(AXGN) | COM | 05463X106 | $48.7M | 2,955,943 | 3.1% |
| Iovance Biotherapeutics Inc(IOVA) | COM | 462260100 | $48.5M | 6,560,000 | 3.1% |
| Teva Pharmaceutical Inds LTD(TEVA) | SPONSORED ADS | 881624209 | $46.1M | 2,093,000 | 2.9% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $45.1M | 8,142,500 | 2.8% |
| Organogenesis Hldgs Inc(ORGO) | COM | 68621F102 | $40.0M | 12,484,876 | 2.5% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $39.6M | 2,102,833 | 2.5% |
| United Therapeutics Corp del(UTHR) | COM | 91307C102 | $38.6M | 109,394 | 2.4% |
| Celcuity Inc(CELC) | COM | 15102K100 | $33.6M | 2,565,087 | 2.1% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $32.9M | 2,492,000 | 2.1% |
| Jasper Therapeutics Inc(JSPR) | COM NEW | 471871202 | $32.0M | 1,494,420 | 2.0% |
| Integra Lifesciences Hldgs C(IART) | COM NEW | 457985208 | $28.9M | 1,276,000 | 1.8% |
| Neuropace Inc(NPCE) | COM | 641288105 | $27.2M | 2,433,168 | 1.7% |
| Astrazeneca PLC(AZN) | SPONSORED ADR | 046353108 | $26.8M | 409,000 | 1.7% |
| C4 Therapeutics Inc(CCCC) | COM STK | 12529R107 | $25.1M | 6,978,942 | 1.6% |
| Quidelortho Corp(QDEL) | COM | 219798105 | $24.4M | 547,082 | 1.5% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $22.1M | 320,272 | 1.4% |
| Inhibikase Therapeutics Inc(IKT) | COM NEW | 45719W205 | $20.6M | 6,325,000 | 1.3% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $19.8M | 144,000 | 1.2% |
| Rigel Pharmaceuticals Inc(RIGL) | COM | 766559702 | $19.0M | 1,130,679 | 1.2% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $18.7M | 243,540 | 1.2% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $18.1M | 76,800 | 1.1% |
| Adaptive Biotechnologies COR(ADPT) | COM | 00650F109 | $17.9M | 2,983,142 | 1.1% |
| Edap TMS S A(EDA) | SPONSORED ADR | 268311107 | $16.2M | 7,309,254 | 1.0% |
| Takeda Pharmaceutical Co LTD(TAK) | SPONSORED ADS | 874060205 | $15.6M | 1,180,000 | 1.0% |
| Pharvaris N V(PHVS) | COM | N69605108 | $15.6M | 814,652 | 1.0% |
| Surmodics Inc(SU6) | COM | 868873100 | $15.6M | 394,060 | 1.0% |
| Septerna Inc(SEPN) | COM | 81734D104 | $15.5M | 675,409 | 1.0% |
| Merus N V | COM | N5749R100 | $13.1M | 312,321 | 0.8% |
| Orthofix MED Inc(OFIX) | COM | 68752M108 | $12.0M | 686,374 | 0.8% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $11.3M | 205,294 | 0.7% |
| Verastem Inc(VSTM) | COM NEW | 92337C203 | $11.3M | 2,184,026 | 0.7% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $10.6M | 275,000 | 0.7% |
| Delcath SYS Inc(DCTH) | COM NEW | 24661P807 | $9.6M | 801,000 | 0.6% |
| CG Oncology Inc(CGON) | COM | 156944100 | $9.4M | 328,585 | 0.6% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $9.3M | 121,031 | 0.6% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $9.0M | 11,658 | 0.6% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $8.8M | 201,084 | 0.6% |
| Theratechnologies Inc(TQ80) | COM NEW | 88338H704 | $8.7M | 4,801,376 | 0.5% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $8.2M | 104,357 | 0.5% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $8.1M | 99,050 | 0.5% |
| Evolus Inc(EOLS) | COM | 30052C107 | $7.7M | 697,158 | 0.5% |
| Immunic Inc(IMUX) | COM | 4525EP101 | $7.3M | 7,293,007 | 0.5% |
| Scholar Rock Hldg Corp(SRRK) | COM | 80706P103 | $7.2M | 167,543 | 0.5% |
| Castle Biosciences Inc(CSTL) | COM | 14843C105 | $6.7M | 252,917 | 0.4% |