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Paradigm Biocapital Advisors LP

Q1 2025 Holdings

Filed 2025-05-15 | 28 holdings | $2.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↓Shares% Portfolio
Nuvalent Inc(NUVL)COM670703107$373.7M5,269,43317.1%
Arcellx Inc(ACLX)COMMON STOCK03940C100$294.7M4,492,03213.5%
Revolution Medicines Inc(RVMD)COM76155X100$218.5M6,178,11110.0%
Beigene LTD(ONC)SPONSORED ADS07725L102$181.3M666,0248.3%
Merus N VCOMN5749R100$141.8M3,369,6996.5%
Tarsus Pharmaceuticals Inc(TARS)COM87650L103$134.1M2,610,1976.1%
Edgewise Therapeutics Inc(EWTX)COM28036F105$96.7M4,394,5564.4%
Janux Therapeutics Inc(JANX)COM47103J105$89.9M3,329,9094.1%
Crinetics Pharmaceuticals in(CRNX)COM22663K107$65.3M1,946,1683.0%
Vaxcyte Inc(PCVX)COM92243G108$64.1M1,696,4812.9%
Disc Medicine Inc(IRON)COM254604101$60.1M1,210,9712.8%
Cogent Biosciences Inc(COGT)COM19240Q201$53.7M8,963,6552.5%
Lenz Therapeutics Inc(LENZ)COM52635N103$38.9M1,511,9321.8%
Apogee Therapeutics Inc(APGE)COM03770N101$35.9M961,7071.6%
Argenx SE(ARGX)SPONSORED ADR04016X101$35.3M59,6791.6%
Cytokinetics Inc(CYTK)COM NEW23282W605$34.5M858,6641.6%
Insmed Inc(INSM)COM PAR $.01457669307$34.4M451,3591.6%
Spyre Therapeutics Inc(SYRE)COM NEW00773J202$34.3M2,127,2051.6%
Metsera IncCOM59267L107$32.4M1,191,4621.5%
Viridian Therapeutics Inc(VRDN)COM92790C104$28.2M2,095,0791.3%
Olema Pharmaceuticals Inc(OLMA)COM68062P106$25.3M6,741,1721.2%
Moonlake Immunotherapeutics(MLTX)CLASS A ORD61559X104$24.5M627,4231.1%
Arcutis Biotherapeutics Inc(ARQT)COM03969K108$22.9M1,465,3341.0%
Y-Mabs Therapeutics Inc(YMABUSD)COM984241109$18.8M4,236,3460.9%
Erasca Inc(ERAS)COM29479A108$14.8M10,802,3540.7%
Edgewise Therapeutics Inc(EWTX)CallCOM28036F105$11.0M500,0000.5%
Ocular Therapeutix Inc(OCUL)COM67576A100$9.6M1,314,0180.4%
Immatics N.v(IMTX)SHSN44445109$8.6M1,907,1080.4%