Q1 2026 Holdings
Filed 2026-05-15 | 63 holdings | $6.1B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr Series Trust(XBI)Put | STATE STREET SPD | 78464A870 | $1.3B | 10,000,000 | 20.9% |
| Guardant Health Inc(GH) | COM | 40131M109 | $308.4M | 3,338,241 | 5.0% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $286.3M | 11,526,971 | 4.7% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $252.5M | 3,600,000 | 4.1% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $249.9M | 4,300,000 | 4.1% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $206.3M | 4,279,848 | 3.4% |
| Axsome Therapeutics Inc.(AXSM) | COM | 05464T104 | $185.9M | 1,100,000 | 3.0% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $182.3M | 4,532,374 | 3.0% |
| Ocular Therapeutix Inc(OCUL) | COM | 67576A100 | $166.7M | 19,686,282 | 2.7% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $165.2M | 4,106,067 | 2.7% |
| Alumis Inc(ALMS) | COM | 022307102 | $149.2M | 6,772,595 | 2.4% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $146.4M | 1,950,000 | 2.4% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $141.0M | 1,376,324 | 2.3% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $127.0M | 3,590,323 | 2.1% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $125.4M | 3,158,041 | 2.0% |
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $119.5M | 6,408,863 | 2.0% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $103.8M | 3,477,562 | 1.7% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $99.8M | 2,034,203 | 1.6% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $98.4M | 6,345,244 | 1.6% |
| Genmab A/S(GMAB) | SPONSORED ADS | 372303206 | $98.3M | 3,663,250 | 1.6% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $90.6M | 1,374,320 | 1.5% |
| Grail Inc(GRAL) | COM | 384747101 | $89.0M | 1,722,797 | 1.5% |
| LB Pharmaceuticals Inc(LBRX) | COM SHS | 50180M108 | $82.7M | 3,352,804 | 1.4% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $82.3M | 2,757,569 | 1.3% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $80.8M | 4,062,500 | 1.3% |
| Compass Pathways PLC(CMPS) | SPONSORED ADS | 20451W101 | $67.3M | 12,161,496 | 1.1% |
| Biomarin Pharmaceutical Inc(BMRN) | COM | 09061G101 | $65.0M | 1,150,000 | 1.1% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $62.5M | 841,445 | 1.0% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $58.2M | 1,931,884 | 1.0% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $57.5M | 2,750,000 | 0.9% |
| Definium Therapeutics Inc(DFTX) | COM SHS | 24477V105 | $56.7M | 3,000,000 | 0.9% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $56.6M | 1,073,877 | 0.9% |
| Geron Corp(GERN) | COM | 374163103 | $47.3M | 31,720,278 | 0.8% |
| ANI Pharmaceuticals Inc(ANIP) | COM | 00182C103 | $46.1M | 600,000 | 0.8% |
| Cormedix Inc(CRMD) | COM | 21900C308 | $42.6M | 6,274,076 | 0.7% |
| Ataibeckley Inc(ATAI) | COM SHS | 04650F101 | $42.5M | 12,000,000 | 0.7% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $40.7M | 1,283,979 | 0.7% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $38.5M | 1,000,000 | 0.6% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $36.5M | 2,491,539 | 0.6% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $36.3M | 2,000,000 | 0.6% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $36.1M | 1,078,710 | 0.6% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $35.0M | 9,345,000 | 0.6% |
| Veradermics Inc(MANE) | COMMON STOCK | 922967104 | $31.6M | 500,000 | 0.5% |
| Verastem Inc(VSTM) | COM NEW | 92337C203 | $30.4M | 5,740,850 | 0.5% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $29.8M | 4,377,572 | 0.5% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $27.3M | 1,393,944 | 0.4% |
| X4 Pharmaceuticals Inc(XFOR) | COM NEW | 98420X202 | $26.2M | 6,339,535 | 0.4% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $25.7M | 3,565,062 | 0.4% |
| Enanta Pharmaceuticals Inc(ENTA) | COM | 29251M106 | $24.7M | 1,956,867 | 0.4% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $24.0M | 285,000 | 0.4% |