Q1 2025 Holdings
Filed 2025-05-14 | 98 holdings | $1.0B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr S&P 500 ETF TR(SPY)Put | TR UNIT | 78462F103 | $223.8M | 400,000 | 21.4% |
| Ishares TR(IWM)Put | RUSSELL 2000 ETF | 464287655 | $59.8M | 300,000 | 5.7% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $44.6M | 1,328,175 | 4.3% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $43.0M | 1,151,199 | 4.1% |
| Spdr Series Trust(XBI)Put | S&P BIOTECH | 78464A870 | $40.6M | 500,000 | 3.9% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $39.0M | 615,000 | 3.7% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $34.8M | 530,000 | 3.3% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $33.0M | 1,000,000 | 3.2% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $32.6M | 460,000 | 3.1% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $26.5M | 80,000 | 2.5% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $22.2M | 1,546,662 | 2.1% |
| Amgen Inc(AMGN)Call | COM | 031162100 | $21.8M | 70,000 | 2.1% |
| Teva Pharmaceutical Inds LTD(TEVA) | SPONSORED ADS | 881624209 | $21.5M | 1,400,000 | 2.1% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $19.3M | 400,000 | 1.8% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $19.2M | 1,070,000 | 1.8% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $17.5M | 1,100,000 | 1.7% |
| Spdr S&P 500 ETF TR(SPY) | TR UNIT | 78462F103 | $16.8M | 30,000 | 1.6% |
| Alnylam Pharmaceuticals Inc(ALNY)Call | COM | 02043Q107 | $14.9M | 55,000 | 1.4% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $14.7M | 1,825,000 | 1.4% |
| Omeros Corp | NOTE 5.250% 2/1 | 682143AG7 | $14.3M | $15,525,000 | 1.4% |
| Merus N V | COM | N5749R100 | $13.6M | 321,962 | 1.3% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $11.7M | 100,000 | 1.1% |
| Karyopharm Therapeutics Inc | NOTE 3.000%10/1 | 48576UAA4 | $11.6M | $15,250,000 | 1.1% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $11.4M | 280,000 | 1.1% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $10.7M | 140,000 | 1.0% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $10.4M | 300,000 | 1.0% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $9.6M | 810,669 | 0.9% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $8.5M | 355,143 | 0.8% |
| Protagonist Therapeutics Inc(PTGX)Call | COM | 74366E102 | $8.3M | 172,500 | 0.8% |
| Corcept Therapeutics Inc(CORT)Call | COM | 218352102 | $8.0M | 70,000 | 0.8% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $7.9M | 1,250,000 | 0.8% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $7.8M | 481,678 | 0.7% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $7.3M | 430,000 | 0.7% |
| Travere Therapeutics Inc | NOTE 2.250% 3/0 | 89422GAA5 | $7.0M | $7,000,000 | 0.7% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $6.7M | 325,000 | 0.6% |
| Vera Therapeutics Inc(VERA)Call | CL A | 92337R101 | $6.4M | 265,000 | 0.6% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $5.6M | 545,362 | 0.5% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $5.5M | 50,000 | 0.5% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $5.3M | 657,154 | 0.5% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $5.3M | 390,000 | 0.5% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $5.1M | 1,480,881 | 0.5% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $5.1M | 152,252 | 0.5% |
| Exelixis Inc(EXEL)Call | COM | 30161Q104 | $5.0M | 135,000 | 0.5% |
| Rezolute Inc(RZLT) | COM NEW | 76200L309 | $4.9M | 1,700,000 | 0.5% |
| Perspective Therapeutics Inc(CATX) | COM NEW | 46489V302 | $4.7M | 2,224,196 | 0.5% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $4.7M | 3,045,000 | 0.5% |
| Erasca Inc(ERAS) | COM | 29479A108 | $4.6M | 3,341,519 | 0.4% |
| Edgewise Therapeutics Inc(EWTX)Put | COM | 28036F105 | $4.4M | 200,000 | 0.4% |
| Proqr Thrapeutics N V | SHS EURO | N71542109 | $4.4M | 3,284,512 | 0.4% |
| Uniqure NV(QURE) | SHS | N90064101 | $4.2M | 400,000 | 0.4% |