Q4 2022 Holdings
Filed 2023-02-14 | 71 holdings | $1.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Prometheus Biosciences Inc | COM | 74349U108 | $208.7M | 1,897,500 | 11.0% |
| BeiGene Ltd(ONC) | SPONSORED ADR | 07725L102 | $110.0M | 500,000 | 5.8% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $96.2M | 2,100,000 | 5.1% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $94.9M | 3,984,264 | 5.0% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $90.6M | 2,000,000 | 4.8% |
| Springworks Therapeutics Inc | COM | 85205L107 | $89.0M | 3,421,541 | 4.7% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $81.5M | 1,576,000 | 4.3% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $77.0M | 2,084,000 | 4.1% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $51.6M | 7,123,642 | 2.7% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $49.0M | 6,448,359 | 2.6% |
| Reata Pharmaceuticals Inc(RETAEUR) | CL A | 75615P103 | $46.7M | 1,230,004 | 2.5% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $45.6M | 831,495 | 2.4% |
| iTeos Therapeutics Inc(5E7) | COM | 46565G104 | $42.1M | 2,154,058 | 2.2% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $41.7M | 1,094,000 | 2.2% |
| AnaptysBio Inc(ANAB) | COM | 032724106 | $40.3M | 1,300,000 | 2.1% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $40.0M | 2,202,812 | 2.1% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $38.8M | 1,251,137 | 2.0% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $36.0M | 1,210,192 | 1.9% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $32.4M | 2,169,132 | 1.7% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $30.9M | 400,000 | 1.6% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $29.6M | 1,432,200 | 1.6% |
| Merus N V | COM | N5749R100 | $29.4M | 1,900,000 | 1.5% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $28.7M | 1,466,051 | 1.5% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $28.4M | 2,325,000 | 1.5% |
| Ventyx Biosciences Inc(VTYX) | COM | 92332V107 | $27.9M | 850,000 | 1.5% |
| PMV Pharmaceuticals Inc(PMVP) | COM | 69353Y103 | $27.5M | 3,163,795 | 1.5% |
| Bellus Health Inc New(BLU) | COM NEW | 07987C204 | $26.3M | 3,200,000 | 1.4% |
| Day One Biopharmaceuticals I(DAWN) | COM | 23954D109 | $25.6M | 1,189,943 | 1.4% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $24.9M | 1,121,327 | 1.3% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $23.7M | 600,000 | 1.2% |
| Geron Corp(GERN) | COM | 374163103 | $19.6M | 8,100,000 | 1.0% |
| Exelixis Inc(EXEL) | COM | 30161Q104 | $18.4M | 1,150,000 | 1.0% |
| Point Biopharma Global Inc | COM | 730541109 | $18.2M | 2,500,000 | 1.0% |
| Prothena Corp PLC(PRTA) | SHS | G72800108 | $18.1M | 300,000 | 1.0% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $17.8M | 1,400,000 | 0.9% |
| Iveric Bio Inc(OPHTEUR) | COM | 46583P102 | $17.7M | 825,000 | 0.9% |
| Rain Oncology Inc | COM | 75082Q105 | $17.2M | 2,147,212 | 0.9% |
| Viking Therapeutics Inc(VKTX) | COM | 92686J106 | $14.1M | 1,500,000 | 0.7% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $13.4M | 1,224,892 | 0.7% |
| Fate Therapeutics Inc(FATE) | COM | 31189P102 | $12.6M | 1,250,000 | 0.7% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $11.6M | 95,000 | 0.6% |
| Cullinan Oncology Inc(CGEM) | COM | 230031106 | $11.3M | 1,074,082 | 0.6% |
| Iovance Biotherapeutics Inc(IOVA) | COM | 462260100 | $9.6M | 1,505,133 | 0.5% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $7.4M | 1,054,000 | 0.4% |
| Gossamer Bio Inc(GOSS) | COM | 38341P102 | $7.2M | 3,336,928 | 0.4% |
| Panacea Acquisition Corp II | CL A SHS | G6882C106 | $6.2M | 500,000 | 0.3% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $6.1M | 525,000 | 0.3% |
| BioAtla Inc(BCAB) | COM | 09077B104 | $5.7M | 686,347 | 0.3% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $5.1M | 150,000 | 0.3% |
| Cabaletta Bio Inc(CABA) | COM | 12674W109 | $5.0M | 540,000 | 0.3% |