Q4 2022 Holdings
Filed 2023-02-14 | 78 holdings | $2.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Moonlake Immunotherapeutics(MLTX) | CLASS A ORD | 61559X104 | $228.4M | 21,751,284 | 9.6% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $135.4M | 1,755,000 | 5.7% |
| Repare Therapeutics Inc(RPTX) | COM | 760273102 | $122.0M | 8,291,988 | 5.1% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $117.1M | 4,692,604 | 4.9% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $89.7M | 9,275,158 | 3.8% |
| 4D Molecular Therapeutics in(FDMT) | COM | 35104E100 | $89.0M | 4,007,413 | 3.8% |
| Cullinan Oncology Inc(CGEM) | COM | 230031106 | $79.2M | 7,509,059 | 3.3% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $77.5M | 3,255,588 | 3.3% |
| Point Biopharma Global Inc | COM | 730541109 | $66.9M | 9,177,748 | 2.8% |
| Xoma Corp del(XOMA) | COM NEW | 98419J206 | $66.5M | 3,611,494 | 2.8% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $57.9M | 3,876,021 | 2.4% |
| CTI Biopharma Corp(CTIC1USD) | COM | 12648L601 | $53.0M | 8,813,021 | 2.2% |
| Aclaris Therapeutics Inc(ACRS) | COM | 00461U105 | $51.6M | 3,276,543 | 2.2% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $50.1M | 1,271,243 | 2.1% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $50.1M | 2,736,613 | 2.1% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $47.6M | 2,303,520 | 2.0% |
| Kura Oncology Inc(KURA) | COM | 50127T109 | $47.2M | 3,800,983 | 2.0% |
| Zymeworks del Inc(ZYME) | COM | 98985Y108 | $46.1M | 5,870,000 | 1.9% |
| Merus N V | COM | N5749R100 | $46.1M | 2,978,420 | 1.9% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $45.5M | 2,561,000 | 1.9% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $42.4M | 1,121,809 | 1.8% |
| Allakos Inc(ALLKGUSD) | COM | 01671P100 | $42.2M | 5,006,921 | 1.8% |
| Replimune Group Inc(REPL) | COM | 76029N106 | $41.4M | 1,522,629 | 1.7% |
| Ideaya Biosciences Inc(IDYA) | COM | 45166A102 | $40.1M | 2,205,089 | 1.7% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $36.9M | 1,451,197 | 1.6% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $36.2M | 1,238,974 | 1.5% |
| Iteos Therapeutics Inc(5E7) | COM | 46565G104 | $35.4M | 1,810,835 | 1.5% |
| Lexicon Pharmaceuticals Inc(LXRX) | COM NEW | 528872302 | $30.8M | 16,149,179 | 1.3% |
| Glycomimetics Inc(GLYCEUR) | COM | 38000Q102 | $28.9M | 9,544,262 | 1.2% |
| Rain Oncology Inc | COM | 75082Q105 | $28.2M | 3,526,729 | 1.2% |
| Sutro Biopharma Inc | COM | 869367102 | $27.1M | 3,347,946 | 1.1% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $23.0M | 1,508,416 | 1.0% |
| Vigil Neuroscience Inc(VIGL) | COM | 92673K108 | $22.7M | 1,813,633 | 1.0% |
| Essa Pharma Inc(EPIEUR) | COM NEW | 29668H708 | $22.0M | 8,748,629 | 0.9% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $21.4M | 6,894,345 | 0.9% |
| Concert Pharmaceuticals Inc(CNCEEUR) | COM | 206022105 | $21.2M | 3,629,000 | 0.9% |
| Annexon Inc(ANNX) | COM | 03589W102 | $19.5M | 3,780,694 | 0.8% |
| Janux Therapeutics Inc(JANX) | COM | 47103J105 | $19.4M | 1,470,334 | 0.8% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $18.8M | 2,472,327 | 0.8% |
| Third Harmonic BIO Inc(THRD) | COM | 88427A107 | $18.8M | 4,365,933 | 0.8% |
| Olema Pharmaceuticals Inc(OLMA) | COM | 68062P106 | $18.6M | 7,611,503 | 0.8% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $16.0M | 1,521,948 | 0.7% |
| AC Immune SA(ACIU) | SHS | H00263105 | $15.2M | 7,428,379 | 0.6% |
| An2 Therapeutics Inc(ANTX) | COM | 037326105 | $14.9M | 1,563,963 | 0.6% |
| Calliditas Therapeutics AB | SPONSERED ADS | 13124Q106 | $13.1M | 750,000 | 0.6% |
| Ovid Therapeutics Inc(OVID) | COM | 690469101 | $12.7M | 6,851,051 | 0.5% |
| Verve Therapeutics Inc | COM | 92539P101 | $12.6M | 650,000 | 0.5% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $11.4M | 984,824 | 0.5% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $10.6M | 6,595,801 | 0.4% |
| Alpine Immune Sciences Inc(NVLSEUR) | COM | 02083G100 | $8.3M | 1,135,940 | 0.4% |