Q4 2023 Holdings
Filed 2024-02-14 | 101 holdings | $4.5B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2024-02-26) | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Cerevel Therapeutics Hldng I(CERE1EUR) | COM | 15678U128 | $464.9M | 10,965,193 | 10.4% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $398.1M | 28,057,456 | 8.9% |
| Lianbio | SPONSORED ADS | 53000N108 | $257.3M | 57,558,451 | 5.7% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $252.2M | 4,544,809 | 5.6% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $214.7M | 2,917,991 | 4.8% |
| Inhibrx Inc(INBXUSD) | COM | 45720L107 | $161.7M | 4,256,104 | 3.6% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $123.8M | 3,074,542 | 2.8% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $99.0M | 2,154,110 | 2.2% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $98.1M | 2,328,082 | 2.2% |
| Iovance Biotherapeutics Inc(IOVA) | COM | 462260100 | $97.4M | 11,979,415 | 2.2% |
| Cymabay Therapeutics Inc(CBAYUSD) | COM | 23257D103 | $95.1M | 4,024,400 | 2.1% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $82.6M | 1,038,019 | 1.8% |
| Medtronic PLC(MDT) | SHS | G5960L103 | $80.5M | 976,652 | 1.8% |
| Cargo Therapeutics Inc(CRGX) | COM | 14179K101 | $79.6M | 3,436,600 | 1.8% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $79.5M | 11,331,103 | 1.8% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $76.9M | 3,866,214 | 1.7% |
| Biohaven LTD(BHVN) | COM | G1110E107 | $73.8M | 1,725,047 | 1.6% |
| Springworks Therapeutics Inc | COM | 85205L107 | $71.4M | 1,957,246 | 1.6% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $70.6M | 1,748,933 | 1.6% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $68.4M | 1,088,486 | 1.5% |
| Lyra Therapeutics Inc(LYRA) | COM | 55234L105 | $66.8M | 12,757,562 | 1.5% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $59.1M | 1,023,045 | 1.3% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $56.1M | 2,606,679 | 1.3% |
| Natera Inc(NTRA) | COM | 632307104 | $53.3M | 850,225 | 1.2% |
| Rapt Therapeutics Inc(RAPTEUR) | COM | 75382E109 | $53.2M | 2,139,950 | 1.2% |
| Verrica Pharmaceuticals Inc | COM | 92511W108 | $52.0M | 7,099,182 | 1.2% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $51.2M | 1,707,398 | 1.1% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $51.1M | 1,827,901 | 1.1% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $50.7M | 1,100,748 | 1.1% |
| Rayzebio Inc | COM | 75525N107 | $46.3M | 744,056 | 1.0% |
| Cabaletta BIO Inc(CABA) | COM | 12674W109 | $45.5M | 2,003,058 | 1.0% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $44.7M | 1,255,512 | 1.0% |
| Sarepta Therapeutics Inc(SRPT) | COM | 803607100 | $43.6M | 451,873 | 1.0% |
| Evolus Inc(EOLS) | COM | 30052C107 | $41.7M | 3,963,424 | 0.9% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $37.7M | 1,730,212 | 0.8% |
| Nautilus Biotechnology Inc(NAUT) | COM | 63909J108 | $37.7M | 12,594,211 | 0.8% |
| Abbvie Inc(ABBV) | COM | 00287Y109 | $36.9M | 238,000 | 0.8% |
| Immatics N.v(IMTX) | SHS | N44445109 | $36.8M | 3,491,500 | 0.8% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $35.7M | 270,794 | 0.8% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $35.0M | 151,151 | 0.8% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $30.8M | 4,004,070 | 0.7% |
| Aldeyra Therapeutics Inc(ALDX) | COM | 01438T106 | $30.2M | 8,593,586 | 0.7% |
| Adma Biologics Inc(ADMA) | COM | 000899104 | $29.1M | 6,433,369 | 0.6% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $27.5M | 1,869,125 | 0.6% |
| Fusion Pharmaceuticals Inc | COM | 36118A100 | $26.4M | 2,751,395 | 0.6% |
| Tarsus Pharmaceuticals(TARS) | COM | 87650L103 | $26.3M | 1,296,416 | 0.6% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $23.5M | 818,882 | 0.5% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $22.6M | 967,775 | 0.5% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $22.2M | 2,432,089 | 0.5% |
| Celcuity Inc(CELC) | COM | 15102K100 | $21.6M | 1,481,300 | 0.5% |