Q2 2025 Holdings
Filed 2025-08-14 | 85 holdings | $2.7B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $520.9M | 5,507,591 | 19.3% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $166.4M | 963,886 | 6.2% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $163.2M | 2,478,000 | 6.0% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $152.8M | 2,418,299 | 5.7% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $104.9M | 1,375,180 | 3.9% |
| Artivion Inc(AORT) | COM | 228903100 | $86.9M | 2,793,703 | 3.2% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $82.2M | 12,626,103 | 3.0% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $65.4M | 650,252 | 2.4% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $60.8M | 4,639,949 | 2.3% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $59.4M | 1,074,448 | 2.2% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $58.0M | 11,906,646 | 2.1% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $51.3M | 1,182,148 | 1.9% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $50.7M | 7,902,365 | 1.9% |
| Immatics N.v(IMTX) | SHS | N44445109 | $50.5M | 9,383,456 | 1.9% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $48.9M | 915,887 | 1.8% |
| Omada Health Inc(OMDA) | COM | 68170A108 | $44.4M | 2,426,330 | 1.6% |
| Amicus Therapeutics Inc(FOLD) | COM | 03152W109 | $42.5M | 7,412,830 | 1.6% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $37.5M | 3,331,465 | 1.4% |
| Merus N V | COM | N5749R100 | $37.3M | 708,176 | 1.4% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $36.1M | 430,439 | 1.3% |
| Astria Therapeutics Inc(CATBUSD) | COM | 04635X102 | $34.8M | 6,485,420 | 1.3% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $34.2M | 2,137,890 | 1.3% |
| Neurocrine Biosciences Inc(NBIX) | COM | 64125C109 | $32.1M | 255,050 | 1.2% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $31.7M | 752,921 | 1.2% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $30.1M | 280,000 | 1.1% |
| Caris Life Sciences Inc(CAI) | COM | 142152107 | $29.3M | 1,098,163 | 1.1% |
| Spdr Series Trust(XBI)Put | S&P BIOTECH | 78464A870 | $24.9M | 300,000 | 0.9% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $24.5M | 45,119 | 0.9% |
| Adma Biologics Inc(ADMA) | COM | 000899104 | $23.7M | 1,303,468 | 0.9% |
| Beta Bionics Inc(BBNX) | COM NEW | 08659B102 | $23.2M | 1,593,608 | 0.9% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $22.9M | 1,529,445 | 0.8% |
| Evolus Inc(EOLS) | COM | 30052C107 | $22.8M | 2,474,843 | 0.8% |
| Celcuity Inc(CELC) | COM | 15102K100 | $21.8M | 1,633,208 | 0.8% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $21.4M | 2,247,390 | 0.8% |
| Sionna Therapeutics Inc(SION) | COM | 829401108 | $21.1M | 1,216,045 | 0.8% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $20.7M | 198,534 | 0.8% |
| Repligen Corp(RGEN) | COM | 759916109 | $20.6M | 166,000 | 0.8% |
| Insulet Corp(PODD) | COM | 45784P101 | $19.0M | 60,387 | 0.7% |
| Outset MED Inc(OM) | COM | 690145206 | $16.0M | 833,333 | 0.6% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $16.0M | 1,275,274 | 0.6% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $15.9M | 6,993,646 | 0.6% |
| Aldeyra Therapeutics Inc(ALDX) | COM | 01438T106 | $15.5M | 4,051,631 | 0.6% |
| Charles RIV Labs Intl Inc(CRL) | COM | 159864107 | $15.2M | 100,000 | 0.6% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $15.1M | 1,146,935 | 0.6% |
| Inhibrx Biosciences Inc(INBX) | COM | 45720N103 | $14.0M | 977,892 | 0.5% |
| Adagio MED Hldgs Inc(ADGM) | COM | 00534B100 | $12.8M | 9,876,576 | 0.5% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $12.5M | 1,096,985 | 0.5% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $12.3M | 834,252 | 0.5% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $12.3M | 4,592,556 | 0.5% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $11.0M | 420,690 | 0.4% |