Q1 2026 Holdings
Filed 2026-05-15 | 94 holdings | $5.1B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2026-05-29) | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $656.0M | 2,035,986 | 12.8% |
| Celcuity Inc(CELC) | COM | 15102K100 | $356.9M | 3,127,200 | 7.0% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $350.3M | 1,531,421 | 6.8% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $229.5M | 8,285,461 | 4.5% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $208.9M | 5,258,903 | 4.1% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $206.4M | 2,373,795 | 4.0% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $190.8M | 3,783,225 | 3.7% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $161.9M | 1,580,505 | 3.2% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $139.4M | 4,423,974 | 2.7% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $129.7M | 1,230,879 | 2.5% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $129.7M | 1,540,384 | 2.5% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $123.1M | 4,142,551 | 2.4% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $115.2M | 8,284,882 | 2.3% |
| Immatics N.v(IMTX) | SHS | N44445109 | $102.2M | 10,383,456 | 2.0% |
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $97.0M | 9,751,141 | 1.9% |
| Inhibrx Biosciences Inc(INBX) | COM | 45720N103 | $97.0M | 1,442,707 | 1.9% |
| Meiragtx Hldgs PLC(MGTX) | COM | G59665102 | $89.3M | 10,326,103 | 1.7% |
| Zymeworks Inc(ZYME) | COM | 98985Y108 | $87.9M | 3,510,078 | 1.7% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $85.7M | 11,906,646 | 1.7% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $84.6M | 4,668,839 | 1.7% |
| Biocryst Pharmaceuticals Inc(BCRX) | COM | 09058V103 | $70.8M | 7,434,033 | 1.4% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $68.4M | 1,395,501 | 1.3% |
| Artivion Inc(AORT) | COM | 228903100 | $60.0M | 1,637,290 | 1.2% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $57.5M | 3,710,877 | 1.1% |
| Moderna Inc(MRNA)Put | COM | 60770K107 | $50.8M | 1,000,000 | 1.0% |
| Nautilus Biotechnology Inc(NAUT) | COM | 63909J108 | $48.9M | 12,594,211 | 1.0% |
| Cytomx Therapeutics Inc.(CTMX) | COM | 23284F105 | $47.5M | 10,098,824 | 0.9% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $45.2M | 2,009,893 | 0.9% |
| Engene Holdings Inc(ENGN) | COM | 29286M105 | $39.7M | 5,827,506 | 0.8% |
| Immunovant Inc(IMVT) | COM | 45258J102 | $39.7M | 1,597,383 | 0.8% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $39.4M | 85,419 | 0.8% |
| Ionis Pharmaceuticals Inc(IONS) | COM | 462222100 | $37.8M | 504,000 | 0.7% |
| DAY One Biopharmaceuticals I(DAWN) | COM | 23954D109 | $37.6M | 1,755,799 | 0.7% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $36.6M | 328,884 | 0.7% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $33.5M | 2,292,441 | 0.7% |
| Repligen Corp(RGEN) | COM | 759916109 | $33.1M | 280,541 | 0.6% |
| Jazz Pharmaceuticals PLC(JAZZ) | SHS USD | G50871105 | $32.1M | 170,000 | 0.6% |
| Damora Therapeutics Inc(GLTO) | COM NEW | 36322Q206 | $31.7M | 1,223,000 | 0.6% |
| X4 Pharmaceuticals Inc(XFOR) | COM NEW | 98420X202 | $27.8M | 6,737,648 | 0.5% |
| Guardant Health Inc(GH) | COM | 40131M109 | $27.7M | 300,000 | 0.5% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $27.5M | 377,544 | 0.5% |
| Invivyd Inc(IVVD) | COM | 00534A102 | $27.1M | 20,859,303 | 0.5% |
| Sionna Therapeutics Inc(SION) | COM | 829401108 | $26.4M | 658,439 | 0.5% |
| Axsome Therapeutics Inc.(AXSM) | COM | 05464T104 | $25.3M | 149,950 | 0.5% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $25.1M | 258,600 | 0.5% |
| SAB Biotherapeutics Inc(SABS) | COM NEW | 78397T202 | $24.6M | 6,431,743 | 0.5% |
| Belite BIO Inc(BLTE) | SPONSORED ADS | 07782B104 | $24.2M | 151,979 | 0.5% |
| Tenax Therapeutics Inc(TENX) | COM NEW | 88032L605 | $23.2M | 1,447,782 | 0.5% |
| Axogen Inc(AXGN) | COM | 05463X106 | $23.1M | 697,312 | 0.5% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $22.9M | 1,170,829 | 0.4% |