Q1 2026 Holdings
Filed 2026-05-15 | 84 holdings | $17.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Incyte Corporation(INCY) | COM | 45337C102 | $2.9B | 30,744,412 | 16.6% |
| BeOne Medicines Ltd.(ONC) | SPONSORED ADS | 07725L102 | $2.6B | 8,799,053 | 15.0% |
| Insmed Incorporated(INSM) | COM PAR $.01 | 457669307 | $1.2B | 7,421,111 | 7.0% |
| Madrigal Pharmaceuticals, Inc.(MDGL) | COM | 558868105 | $1.1B | 2,141,701 | 6.4% |
| Acadia Pharmaceuticals Inc.(ACAD) | COM | 004225108 | $954.9M | 42,896,690 | 5.5% |
| Revolution Medicines, Inc.(RVMD) | COM | 76155X100 | $929.3M | 9,555,357 | 5.3% |
| Celcuity Inc.(CELC) | COM | 15102K100 | $903.5M | 7,915,792 | 5.2% |
| Kodiak Sciences Inc.(KOD) | COM | 50015M109 | $759.3M | 19,919,186 | 4.4% |
| Kymera Therapeutics, Inc.(KYMR) | COM | 501575104 | $721.1M | 8,657,242 | 4.1% |
| Summit Therapeutics Inc.(SMMT) | COM | 86627T108 | $690.0M | 36,391,063 | 4.0% |
| Praxis Precision Medicines, Inc.(PRAX) | COM | 74006W207 | $564.9M | 1,753,198 | 3.2% |
| Rhythm Pharmaceuticals, Inc.(RYTM) | COM | 76243J105 | $487.4M | 5,604,483 | 2.8% |
| Alkermes plc(ALKS) | SHS | G01767105 | $354.0M | 10,012,267 | 2.0% |
| Grail, Inc.(GRAL) | COM | 384747101 | $208.2M | 4,028,614 | 1.2% |
| Edgewise Therapeutics, Inc.(EWTX) | COM | 28036F105 | $207.1M | 6,575,940 | 1.2% |
| Ionis Pharmaceuticals, Inc.(IONS) | COM | 462222100 | $153.8M | 2,047,727 | 0.9% |
| Kiniksa Pharmaceuticals International, plc(KNSA) | ORD SHS CL A | G52694109 | $136.1M | 2,826,246 | 0.8% |
| Immunovant, Inc.(IMVT) | COM | 45258J102 | $135.6M | 5,457,881 | 0.8% |
| Roivant Sciences Ltd.(ROIV) | SHS | G76279101 | $134.8M | 4,867,723 | 0.8% |
| Ideaya Biosciences, Inc.(IDYA) | COM | 45166A102 | $131.5M | 3,946,515 | 0.8% |
| Arrowhead Pharmaceuticals, Inc.(ARWR) | COM | 04280A100 | $124.9M | 1,992,783 | 0.7% |
| Stoke Therapeutics, Inc.(STOK) | COM | 86150R107 | $108.6M | 3,336,697 | 0.6% |
| Immatics N.V.(IMTX) | SHS | N44445109 | $107.4M | 10,916,693 | 0.6% |
| AbCellera Biologics Inc.(ABCL) | COM | 00288U106 | $105.7M | 30,275,938 | 0.6% |
| Abivax S.A.(ABVX) | SPONSORED ADS | 00370M103 | $97.5M | 875,796 | 0.6% |
| Crinetics Pharmaceuticals, Inc.(CRNX) | COM | 22663K107 | $85.4M | 2,351,465 | 0.5% |
| Replimune Group, Inc.(REPL) | COM | 76029N106 | $84.5M | 11,045,336 | 0.5% |
| Celcuity Inc. | Note 2.75% 8/1/2031 | 15102KAA8 | $74.9M | 30,750,000 | 0.4% |
| Nurix Therapeutics, Inc.(NRIX) | COM | 67080M103 | $72.2M | 4,658,556 | 0.4% |
| Denali Therapeutics Inc.(DNLI) | COM | 24823R105 | $71.6M | 3,731,695 | 0.4% |
| Dianthus Therapeutics, Inc.(DNTH) | COM | 252828108 | $71.5M | 852,164 | 0.4% |
| Monte Rosa Therapeutics, Inc.(GLUE) | COM | 61225M102 | $71.5M | 4,345,736 | 0.4% |
| Structure Therapeutics Inc.(GPCR) | SPONSORED ADS | 86366E106 | $69.0M | 1,432,529 | 0.4% |
| Entrada Therapeutics, Inc.(TRDA) | COM | 29384C108 | $64.0M | 5,072,730 | 0.4% |
| Bicycle Therapeutics plc(BCYC) | SPONSORED ADS | 088786108 | $50.5M | 10,885,357 | 0.3% |
| Spyre Therapeutics, Inc.(SYRE) | COM | 00773J202 | $50.4M | 1,000,000 | 0.3% |
| Rapport Therapeutics, Inc.(RAPP) | COM | 75383L102 | $48.4M | 1,547,090 | 0.3% |
| Alumis Inc.(ALMS) | COM | 022307102 | $44.3M | 2,012,500 | 0.3% |
| Mirum Pharmaceuticals, Inc.(MIRM) | COM | 604749101 | $41.2M | 445,975 | 0.2% |
| Viridian Therapeutics, Inc.(VRDN) | COM | 92790C104 | $38.6M | 1,971,678 | 0.2% |
| Enliven Therapeutics, Inc.(ELVN) | COM | 29337E102 | $35.5M | 905,191 | 0.2% |
| Prelude Therapeutics Inc.(PRLD) | COM | 74065P101 | $34.6M | 10,123,824 | 0.2% |
| DBV Technologies S.A.(DBVT) | SPONSORED ADS | 23306J309 | $30.5M | 1,461,425 | 0.2% |
| Design Therapeutics, Inc.(DSGN) | COM | 25056L103 | $27.5M | 2,585,978 | 0.2% |
| Centessa Pharmaceuticals plc(CNTA) | SPONSORED ADS | 152309100 | $26.6M | 670,751 | 0.2% |
| CytomX Therapeutics, Inc.(CTMX) | COM | 23284F105 | $23.4M | 4,975,826 | 0.1% |
| Jade Biosciences, Inc.(JBIO) | COM | 008064206 | $23.1M | 1,641,137 | 0.1% |
| Disc Medicine, Inc.(IRON) | COM | 254604101 | $22.4M | 349,657 | 0.1% |
| Immunocore Holdings plc(IMCR) | ADS | 45258D105 | $22.1M | 734,397 | 0.1% |
| Xenon Pharmaceuticals Inc.(XENE) | COM | 98420N105 | $21.5M | 370,208 | 0.1% |