Q2 2026 Holdings
Filed 2026-08-14 | 129 holdings | $5.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $630.5M | 15,518,492 | 11.7% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $343.9M | 6,776,632 | 6.4% |
| ELI Lilly & Co(LLY) | COM | 532457108 | $309.3M | 257,900 | 5.7% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $189.3M | 3,428,736 | 3.5% |
| Sinovac Biotech LTD(SVA) | SHS | P8696W104 | $184.5M | 2,718,735 | 3.4% |
| Astrazeneca PLC(AZN) | ORD | G0593M107 | $171.1M | 915,700 | 3.2% |
| Structure Therapeutics Inc(GPCR) | SPONSORED ADS | 86366E106 | $118.6M | 2,209,400 | 2.2% |
| Sionna Therapeutics Inc(SION) | COM | 829401108 | $112.4M | 2,555,877 | 2.1% |
| Corvus Pharmaceuticals Inc(CRVS) | COM | 221015100 | $107.0M | 7,165,006 | 2.0% |
| Arrivent Biopharma Inc(AVBP) | COM | 04272N102 | $105.2M | 3,027,328 | 1.9% |
| Guardant Health Inc(GH) | COM | 40131M109 | $87.6M | 583,700 | 1.6% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $86.2M | 92,880 | 1.6% |
| Merck & Co Inc(MRK) | COM | 58933Y105 | $85.2M | 663,400 | 1.6% |
| Uniqure NV(QURE) | SHS | N90064101 | $83.3M | 1,807,486 | 1.5% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $77.0M | 230,100 | 1.4% |
| Edwards Lifesciences Corp(EW) | COM | 28176E108 | $75.5M | 834,900 | 1.4% |
| Prelude Therapeutics Inc(PRLD) | COM | 74065P101 | $73.2M | 13,724,571 | 1.4% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $72.8M | 546,522 | 1.3% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $71.9M | 3,235,684 | 1.3% |
| Natera Inc(NTRA) | COM | 632307104 | $71.1M | 262,000 | 1.3% |
| CG Oncology Inc(CGON) | COM | 156944100 | $69.1M | 972,800 | 1.3% |
| Unitedhealth Group Inc(UNH) | COM | 91324P102 | $67.0M | 161,100 | 1.2% |
| ARS Pharmaceuticals Inc(SPRY) | COM | 82835W108 | $66.4M | 8,288,510 | 1.2% |
| Ascendis Pharma A/S(ASND) | ORD SHS | K08588103 | $65.2M | 244,456 | 1.2% |
| Humana Inc(HUM) | COM | 444859102 | $65.2M | 164,100 | 1.2% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $65.1M | 1,681,300 | 1.2% |
| Boston Scientific Corp(BSX) | COM | 101137107 | $63.3M | 1,483,200 | 1.2% |
| Intuitive Surgical Inc(ISRG) | COM NEW | 46120E602 | $62.8M | 157,900 | 1.2% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $56.9M | 2,110,300 | 1.1% |
| Odyssey Therapeutics Inc(ODTX) | COMMON STOCK | 67613T104 | $56.2M | 3,001,198 | 1.0% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $53.9M | 892,471 | 1.0% |
| Arcutis Biotherapeutics Inc(ARQT) | COM | 03969K108 | $53.5M | 2,042,000 | 1.0% |
| Bristol-Myers Squibb Co(BMY) | COM | 110122108 | $53.3M | 925,000 | 1.0% |
| Q32 BIO Inc(QTTB) | COM | 746964105 | $52.6M | 4,127,987 | 1.0% |
| Stryker Corporation(SYK) | COM | 863667101 | $50.1M | 159,100 | 0.9% |
| Caris Life Sciences Inc(CAI) | COM | 142152107 | $50.0M | 2,806,811 | 0.9% |
| Spdr Series Trust(XBI)Put | ST STR SP BIOT | 78464A870 | $47.5M | 300,000 | 0.9% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $45.5M | 90,700 | 0.8% |
| Palvella Therapeutics Inc NE(PVLA) | COM | 697947109 | $44.7M | 292,360 | 0.8% |
| Elevance Health Inc Formerly(ELV) | COM | 036752103 | $44.4M | 114,700 | 0.8% |
| Shattuck Labs Inc(STTK) | COM | 82024L103 | $43.8M | 6,306,127 | 0.8% |
| Upstream BIO Inc(UPB) | COM | 91678A107 | $39.4M | 5,693,589 | 0.7% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $37.4M | 999,000 | 0.7% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $35.9M | 322,900 | 0.7% |
| Syndax Pharmaceuticals Inc(SNDX) | COM | 87164F105 | $33.7M | 1,542,000 | 0.6% |
| Forte Biosciences Inc(FBRX) | COM NEW | 34962G208 | $33.5M | 1,577,705 | 0.6% |
| Compass Therapeutics Inc(CMPX) | COM | 20454B104 | $33.3M | 15,219,994 | 0.6% |
| Nektar Therapeutics(NKTR) | COM NEW | 640268306 | $32.5M | 465,346 | 0.6% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $30.9M | 83,200 | 0.6% |
| Prelude Therapeutics Inc | NON VOTING | 000000000 | $30.3M | 5,680,186 | 0.6% |