Q1 2026 Holdings
Filed 2026-05-14 | 105 holdings | $1.9B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| State STR Spdr S&P 500 ETF T(SPY)Put | TR UNIT | 78462F103 | $130.1M | 200,000 | 6.7% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $108.2M | 1,284,926 | 5.6% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $97.4M | 1,675,000 | 5.0% |
| Erasca Inc(ERAS) | COM | 29479A108 | $86.6M | 5,350,000 | 4.5% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $78.5M | 480,000 | 4.1% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $77.6M | 2,800,000 | 4.0% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $64.5M | 1,279,134 | 3.3% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $55.6M | 1,400,000 | 2.9% |
| Praxis Precision Medicines I(PRAX) | COM NEW | 74006W207 | $54.8M | 170,000 | 2.8% |
| Anaptysbio Inc(ANAB) | COM | 032724106 | $52.1M | 940,000 | 2.7% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $47.7M | 1,350,000 | 2.5% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $46.2M | 700,483 | 2.4% |
| Abivax SA(ABVX) | SPONSORED ADS | 00370M103 | $45.1M | 405,000 | 2.3% |
| Teva Pharmaceutical Inds LTD(TEVA) | SPONSORED ADS | 881624209 | $42.2M | 1,400,000 | 2.2% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $41.7M | 362,764 | 2.2% |
| Moderna Inc(MRNA)Call | COM | 60770K107 | $40.6M | 800,000 | 2.1% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $30.7M | 300,000 | 1.6% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $29.7M | 562,631 | 1.5% |
| Dianthus Therapeutics Inc(DNTH) | COM | 252828108 | $29.4M | 350,000 | 1.5% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $29.0M | 5,050,211 | 1.5% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $28.9M | 750,000 | 1.5% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $28.8M | 55,000 | 1.5% |
| Sutro Biopharma Inc(STRO) | COM SHS | 869367201 | $26.6M | 1,069,519 | 1.4% |
| Forte Biosciences Inc(FBRX) | COM NEW | 34962G208 | $26.2M | 1,011,890 | 1.4% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $24.5M | 499,673 | 1.3% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $23.9M | 2,000,172 | 1.2% |
| Ovid Therapeutics Inc(OVID) | COM | 690469101 | $23.6M | 10,636,318 | 1.2% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $23.0M | 586,904 | 1.2% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $21.7M | 95,000 | 1.1% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $20.3M | 750,000 | 1.0% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $20.0M | 1,340,840 | 1.0% |
| Bristol-Myers Squibb Co(BMY)Call | COM | 110122108 | $18.2M | 300,000 | 0.9% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $18.1M | 172,125 | 0.9% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $15.9M | 500,000 | 0.8% |
| Zura BIO LTD(ZURA) | CLASS A ORD SHS | G9TY5A101 | $15.3M | 2,564,303 | 0.8% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $15.0M | 967,620 | 0.8% |
| Savara Inc(SVRA) | COM | 805111101 | $13.7M | 2,512,153 | 0.7% |
| Omeros Corp | NOTE 9.500% 6/1 | 682143AK8 | $13.2M | $6,525,000 | 0.7% |
| Perspective Therapeutics Inc(CATX) | COM NEW | 46489V302 | $13.2M | 3,164,582 | 0.7% |
| Helix Acquisition Corp III | USD CL A ORD SHS | G4444S107 | $12.7M | 1,250,000 | 0.7% |
| Arrowhead Pharmaceuticals in(ARWR) | COM | 04280A100 | $12.5M | 200,000 | 0.6% |
| Damora Therapeutics Inc(GLTO) | COM NEW | 36322Q206 | $11.7M | 450,000 | 0.6% |
| Eupraxia Pharmaceuticals Inc(EPRX) | COM | 29842P105 | $11.5M | 1,589,005 | 0.6% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $11.2M | 500,000 | 0.6% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $11.1M | 150,000 | 0.6% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $11.1M | 781,260 | 0.6% |
| Belite BIO Inc(BLTE) | SPONSORED ADS | 07782B104 | $10.4M | 65,000 | 0.5% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $10.2M | 1,401,727 | 0.5% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $10.1M | 250,000 | 0.5% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $9.9M | 257,512 | 0.5% |