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Frazier Management LLC

Q4 2021 Holdings

Filed 2022-02-08 | 43 holdings | $303.1M | 13F-HR | View on SEC ↗ · Holdings Table ↗

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IssuerClassCUSIPValue ↓Shares% Portfolio
Arcutis Biotherapeutics Inc(ARQT)COM03969K108$174.9M8,434,23257.7%
Crinetics Pharmaceuticals in(CRNX)COM22663K107$39.3M1,384,29313.0%
Bicycle Therapeutics PLC(BCYC)SPONSORED ADS088786108$33.8M555,24011.2%
Autolus Therapeutics PLC(AUTL)SPON ADS05280R100$19.4M3,746,8576.4%
Cogent Biosciences Inc(COGT)COM19240Q201$15.2M1,774,8915.0%
Arvinas Inc(ARVN)COM04335A105$13.5M163,7634.4%
Aclaris Therapeutics Inc(ACRS)COM00461U105$5.9M408,3292.0%
Phathom Pharmaceuticals Inc(PHAT)COM71722W107$114.6K5,827,4150.0%
Imago Biosciences IncCOM45250K107$70.4K2,971,2740.0%
Syndax Pharmaceuticals Inc(SNDX)COM87164F105$60.7K2,772,0620.0%
Gritstone BIO Inc(2JQ)COM39868T105$60.0K4,667,2420.0%
Mirum Pharmaceuticals Inc(MIRM)COM604749101$56.9K3,566,9120.0%
Vaxcyte Inc(PCVX)COM92243G108$54.9K2,309,5540.0%
Krystal Biotech Inc(KRYS)COM501147102$53.9K771,2500.0%
Pardes Biosciences IncCOM69945Q105$40.2K2,457,5070.0%
Chinook Therapeutics Inc(290A)COM16961L106$38.7K2,371,9180.0%
Iovance Biotherapeutics Inc(IOVA)COM462260100$33.4K1,747,6220.0%
Tarsus Pharmaceuticals Inc(TARS)COM87650L103$31.9K1,417,1570.0%
Passage BIO IncCOM702712100$31.8K5,009,2190.0%
Anaptysbio Inc(ANAB)COM032724106$31.3K899,7000.0%
Iveric BIO Inc(OPHTEUR)COM46583P102$30.7K1,838,4020.0%
Viridian Therapeutics Inc(VRDN)COM92790C104$29.8K1,505,2000.0%
Sierra Oncology IncCOM NEW82640U404$27.5K1,264,8610.0%
Sutro Biopharma IncCOM869367102$26.4K1,776,4790.0%
Alpine Immune Sciences Inc(NVLSEUR)COM02083G100$24.7K1,784,9130.0%
Silence Therapeutics PLC(SLN)ADS82686Q101$21.2K886,1730.0%
Merus N VCOMN5749R100$17.8K559,1790.0%
Replimune Group Inc(REPL)COM76029N106$17.6K650,8620.0%
Tyra Biosciences Inc(TYRA)COM90240B106$17.6K1,250,0000.0%
Kalvista Pharmaceuticals Inc(KALV)COM483497103$17.3K1,305,0870.0%
Tricida Inc(1T7)COM89610F101$17.1K1,783,8930.0%
Frazier Lifesciences Acqu CoUNIT 12/09/2025G3710A121$14.9K1,501,0000.0%
Gracell Biotechnologies IncSPONSORED ADS38406L103$10.0K1,654,9380.0%
Essa Pharma Inc(EPIEUR)COM NEW29668H708$7.7K543,4700.0%
Regenxbio Inc(RGNX)COM75901B107$7.7K235,8090.0%
Avadel Pharmaceuticals PLCSPONSORED ADR05337M104$7.7K951,8140.0%
Molecular Templates IncCOM608550109$5.4K1,374,0470.0%
Aptinyx IncCOM03836N103$5.0K1,883,2440.0%
Immunovant Inc(IMVT)COM45258J102$5.0K585,7590.0%
Scholar Rock Hldg Corp(SRRK)COM80706P103$3.9K156,0000.0%
Epizyme Inc(EPZMEUR)COM29428V104$1.8K739,3690.0%
Allena Pharmaceuticals(ALNAEUR)COM018119107$9781,651,3570.0%
Nabriva Therapeutics PLCSHSG63637113$255425,6500.0%