Q4 2023 Holdings
Filed 2024-02-14 | 64 holdings | $6.4B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $530.1M | 17,687,772 | 8.3% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $416.5M | 6,096,387 | 6.5% |
| Mirati Therapeutics Inc(MRTXEUR) | COM | 60468T105 | $397.7M | 6,768,514 | 6.2% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $357.3M | 4,489,596 | 5.6% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $352.3M | 11,253,551 | 5.5% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $329.3M | 6,887,086 | 5.1% |
| Alnylam Pharmaceuticals Inc(ALNY) | COM | 02043Q107 | $314.0M | 1,640,559 | 4.9% |
| Argenx SE(ARGX) | SPONSORED ADR | 04016X101 | $253.8M | 667,195 | 4.0% |
| Bruker Corp(BRKR) | COM | 116794108 | $245.7M | 3,344,095 | 3.8% |
| Cytokinetics Inc(CYTK) | COM NEW | 23282W605 | $210.8M | 2,525,080 | 3.3% |
| PTC Therapeutics Inc(PTCT) | COM | 69366J200 | $204.6M | 7,423,970 | 3.2% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $188.6M | 815,191 | 2.9% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $173.4M | 4,213,483 | 2.7% |
| Masimo Corp(MASI) | COM | 574795100 | $171.4M | 1,462,400 | 2.7% |
| Penumbra Inc(PEN) | COM | 70975L107 | $166.7M | 662,664 | 2.6% |
| Natera Inc(NTRA) | COM | 632307104 | $162.4M | 2,593,323 | 2.5% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $137.4M | 3,463,201 | 2.1% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $121.9M | 5,315,514 | 1.9% |
| Cargo Therapeutics Inc(CRGX) | COM | 14179K101 | $119.8M | 5,175,832 | 1.9% |
| Vericel Corp(VCEL) | COM | 92346J108 | $114.4M | 3,212,794 | 1.8% |
| Sage Therapeutics Inc(SG7) | COM | 78667J108 | $112.6M | 5,197,019 | 1.8% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $108.2M | 3,901,523 | 1.7% |
| Avadel Pharmaceuticals PLC | SPONSORED ADR | 05337M104 | $98.1M | 6,947,918 | 1.5% |
| 10X Genomics Inc(TXG) | CL A COM | 88025U109 | $86.7M | 1,549,951 | 1.4% |
| Akero Therapeutics Inc(AKRO) | COM | 00973Y108 | $83.9M | 3,592,759 | 1.3% |
| Merus N V | COM | N5749R100 | $65.3M | 2,373,625 | 1.0% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $64.6M | 2,494,138 | 1.0% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $63.8M | 3,152,341 | 1.0% |
| 89Bio Inc(ETNBGBP) | COM | 282559103 | $62.3M | 5,578,931 | 1.0% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $60.5M | 6,689,789 | 0.9% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $59.9M | 2,142,591 | 0.9% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $57.8M | 1,865,108 | 0.9% |
| Orchestra Biomed Hldgs Inc(OBIO) | COM | 68572M106 | $51.3M | 5,620,640 | 0.8% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $48.0M | 2,232,760 | 0.8% |
| Fulcrum Therapeutics Inc(FULC) | COM | 359616109 | $36.9M | 5,469,956 | 0.6% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $29.9M | 16,893,185 | 0.5% |
| Danaher Corporation(DHR) | COM | 235851102 | $27.4M | 118,584 | 0.4% |
| Thermo Fisher Scientific Inc(TMO) | COM | 883556102 | $26.5M | 50,000 | 0.4% |
| Urogen Pharma LTD(URGN) | COM | M96088105 | $25.9M | 1,726,808 | 0.4% |
| Radnet Inc(RDNT) | COM | 750491102 | $23.1M | 663,602 | 0.4% |
| Springworks Therapeutics Inc | COM | 85205L107 | $22.8M | 625,000 | 0.4% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $21.7M | 4,131,045 | 0.3% |
| Tango Therapeutics Inc(TNGX) | COM | 87583X109 | $19.5M | 1,966,752 | 0.3% |
| GH Research PLC(GHRS) | ORDINARY SHARES | G3855L106 | $19.3M | 3,327,129 | 0.3% |
| Roivant Sciences LTD(ROIV) | SHS | G76279101 | $16.3M | 1,454,273 | 0.3% |
| Immatics N.v(IMTX) | SHS | N44445109 | $15.6M | 1,484,911 | 0.2% |
| Essa Pharma Inc(EPIEUR) | COM NEW | 29668H708 | $15.2M | 2,298,662 | 0.2% |
| Guardant Health Inc(GH) | COM | 40131M109 | $13.3M | 492,977 | 0.2% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $13.2M | 605,816 | 0.2% |
| Allurion Technologies Inc | COM SHS | 02008G102 | $12.9M | 3,457,707 | 0.2% |