Q4 2025 Holdings
Filed 2026-02-17 | 33 holdings | $1.5B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Relay Therapeutics Inc(RLAY) | COM | 75943R102 | $143.8M | 17,000,000 | 9.6% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $99.3M | 3,550,000 | 6.6% |
| Tyra Biosciences Inc(TYRA) | COM | 90240B106 | $88.7M | 3,375,000 | 5.9% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $80.7M | 1,800,000 | 5.4% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $78.2M | 2,388,245 | 5.2% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $78.0M | 2,196,845 | 5.2% |
| Enliven Therapeutics Inc(ELVN) | COM | 29337E102 | $72.3M | 4,692,809 | 4.8% |
| Celldex Therapeutics Inc New(CLDX) | COM NEW | 15117B202 | $69.7M | 2,565,000 | 4.6% |
| Amylyx Pharmaceuticals Inc(AMLX) | COM | 03237H101 | $68.3M | 5,650,000 | 4.5% |
| Terns Pharmaceuticals Inc(TERN) | COM | 880881107 | $59.6M | 1,475,000 | 4.0% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $58.4M | 750,000 | 3.9% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $55.6M | 1,200,000 | 3.7% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $55.3M | 550,000 | 3.7% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $53.1M | 1,753,054 | 3.5% |
| Pharvaris N V(PHVS) | COM | N69605108 | $52.4M | 1,889,445 | 3.5% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $43.2M | 2,275,000 | 2.9% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $39.3M | 450,000 | 2.6% |
| Assembly Biosciences Inc(ASMB) | COM NEW | 045396207 | $34.0M | 1,000,000 | 2.3% |
| LB Pharmaceuticals Inc(LBRX) | COM SHS | 50180M108 | $33.4M | 1,500,000 | 2.2% |
| Cytomx Therapeutics Inc(CTMX) | COM | 23284F105 | $32.8M | 7,692,300 | 2.2% |
| Alto Neuroscience Inc(ANRO) | COM SHS | 02157Q109 | $32.5M | 1,823,196 | 2.2% |
| Palisade BIO Inc(PALI) | COM | 696389402 | $26.9M | 11,445,000 | 1.8% |
| Mind Medicine Mindmed Inc(BRD1EUR) | COM NEW | 60255C885 | $26.8M | 2,000,000 | 1.8% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $25.0M | 1,000,000 | 1.7% |
| Pepgen Inc(PEPG) | COM | 713317105 | $22.1M | 3,400,000 | 1.5% |
| SAB Biotherapeutics Inc(SABS) | COM NEW | 78397T202 | $16.5M | 4,401,500 | 1.1% |
| Replimune Group Inc(REPL) | COM | 76029N106 | $13.9M | 1,425,000 | 0.9% |
| Inhibikase Therapeutics Inc(IKT) | COM NEW | 45719W205 | $11.1M | 5,397,488 | 0.7% |
| Contineum Therapeutics Inc(CTNM) | CL A | 21217B100 | $9.3M | 816,326 | 0.6% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $8.8M | 483,000 | 0.6% |
| Rapt Therapeutics Inc(RAPT) | COM NEW | 75382E208 | $8.5M | 250,000 | 0.6% |
| Athira Pharma Inc(LONA) | COM | 04746L203 | $3.5M | 464,398 | 0.2% |
| Bright Minds Biosciences Inc(DRUG) | COM NEW | 10919W405 | $1.5M | 18,851 | 0.1% |