Q4 2024 Holdings
Filed 2025-02-13 | 85 holdings | $746.0M | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Spdr SER TR(XBI)Put | S&P BIOTECH | 78464A870 | $67.5M | 750,000 | 9.1% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $45.5M | 1,161,237 | 6.1% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $42.2M | 931,728 | 5.7% |
| Arcellx Inc(ACLX) | COMMON STOCK | 03940C100 | $32.6M | 425,000 | 4.4% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $31.6M | 1,100,000 | 4.2% |
| Teva Pharmaceutical Inds LTD(TEVA) | SPONSORED ADS | 881624209 | $30.9M | 1,400,000 | 4.1% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $30.7M | 660,000 | 4.1% |
| Madrigal Pharmaceuticals Inc(MDGL) | COM | 558868105 | $25.5M | 82,500 | 3.4% |
| Crinetics Pharmaceuticals in(CRNX) | COM | 22663K107 | $23.5M | 460,000 | 3.2% |
| Nuvalent Inc(NUVL) | COM | 670703107 | $22.3M | 285,000 | 3.0% |
| Spyre Therapeutics Inc(SYRE) | COM NEW | 00773J202 | $19.2M | 824,328 | 2.6% |
| Wave Life Sciences LTD(WVE) | SHS | Y95308105 | $18.6M | 1,500,000 | 2.5% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $18.4M | 1,095,924 | 2.5% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $18.0M | 425,000 | 2.4% |
| Nurix Therapeutics Inc(NRIX) | COM | 67080M103 | $17.7M | 940,083 | 2.4% |
| Mesoblast LTD(MESO)Put | SPONS ADR | 590717401 | $16.6M | 838,600 | 2.2% |
| Merus N V | COM | N5749R100 | $16.4M | 389,241 | 2.2% |
| Coherus Biosciences Inc | NOTE 1.500% 4/1 | 19249HAB9 | $16.2M | $16,625,000 | 2.2% |
| Omeros Corp | NOTE 5.250% 2/1 | 682143AG7 | $14.6M | $15,525,000 | 2.0% |
| Establishment Labs Hldgs Inc(ESTA) | COM | G31249108 | $12.9M | 279,445 | 1.7% |
| Arvinas Inc(ARVN) | COM | 04335A105 | $12.1M | 630,000 | 1.6% |
| Karyopharm Therapeutics Inc | NOTE 3.000%10/1 | 48576UAA4 | $11.9M | $15,250,000 | 1.6% |
| Inozyme Pharma Inc | COM | 45790W108 | $11.0M | 3,972,318 | 1.5% |
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $10.9M | 425,000 | 1.5% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $10.6M | 4,500,000 | 1.4% |
| Geron Corp(GERN) | COM | 374163103 | $8.0M | 2,250,000 | 1.1% |
| Amgen Inc(AMGN)Call | COM | 031162100 | $7.8M | 30,000 | 1.0% |
| Rezolute Inc(RZLT) | COM NEW | 76200L309 | $7.7M | 1,575,000 | 1.0% |
| Proqr Thrapeutics N V | SHS EURO | N71542109 | $7.5M | 2,825,000 | 1.0% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $7.1M | 368,698 | 1.0% |
| Axsome Therapeutics Inc(AXSM) | COM | 05464T104 | $6.3M | 75,000 | 0.9% |
| Erasca Inc(ERAS) | COM | 29479A108 | $6.3M | 2,499,431 | 0.8% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $5.8M | 130,000 | 0.8% |
| Travere Therapeutics Inc | NOTE 2.250% 3/0 | 89422GAA5 | $5.7M | $6,000,000 | 0.8% |
| Arrowhead Pharmaceuticals in(ARWR) | COM | 04280A100 | $5.6M | 300,000 | 0.8% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $5.5M | 200,000 | 0.7% |
| Neumora Therapeutics Inc.(NMRA)Call | COM | 640979100 | $5.0M | 475,000 | 0.7% |
| Protagonist Therapeutics Inc(PTGX) | COM | 74366E102 | $5.0M | 130,000 | 0.7% |
| Mineralys Therapeutics Inc(MLYS) | COM | 603170101 | $4.3M | 350,000 | 0.6% |
| Perspective Therapeutics Inc(CATX) | COM NEW | 46489V302 | $4.1M | 1,300,000 | 0.6% |
| Cassava Sciences Inc(SAVA)Put | COM | 14817C107 | $4.1M | 1,739,400 | 0.6% |
| Avalo Therapeutics Inc(AVTX) | COM NEW | 05338F306 | $4.1M | 550,765 | 0.5% |
| Perceptive Cap Solutions COR | CL A ORD SHS | G70077105 | $3.6M | 350,000 | 0.5% |
| Travere Therapeutics Inc(TVTX) | COM | 89422G107 | $3.5M | 200,000 | 0.5% |
| Insmed Inc(INSM) | COM PAR $.01 | 457669307 | $3.5M | 50,000 | 0.5% |
| Newamsterdam Pharma Company | *W EXP 99/99/999 | N62509117 | $3.3M | 237,935 | 0.4% |
| Compass Pathways PLC(CMPS) | SPONSORED ADS | 20451W101 | $3.2M | 850,512 | 0.4% |
| Galectin Therapeutics Inc(GALT)Put | COM NEW | 363225202 | $3.2M | 2,492,000 | 0.4% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $3.2M | 263,817 | 0.4% |
| Viridian Therapeutics Inc(VRDN) | COM | 92790C104 | $3.1M | 159,614 | 0.4% |