Q1 2025 Holdings
Filed 2025-05-15 | 47 holdings | $2.2B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Newamsterdam Pharma Company(NAMS) | ORDINARY SHARES | N62509109 | $329.9M | 16,116,418 | 15.1% |
| Mirum Pharmaceuticals Inc(MIRM) | COM | 604749101 | $306.1M | 6,795,121 | 14.0% |
| Verona Pharma PLC(VRNA) | SPONSORED ADS | 925050106 | $219.5M | 3,457,850 | 10.0% |
| Arcutis Biotherapeutics Inc(ARQT) | COM | 03969K108 | $137.4M | 8,785,284 | 6.3% |
| Bridgebio Pharma Inc(BBIO) | COM | 10806X102 | $131.4M | 3,800,457 | 6.0% |
| Krystal Biotech Inc(KRYS) | COM | 501147102 | $124.1M | 688,460 | 5.7% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $87.1M | 1,754,834 | 4.0% |
| Tarsus Pharmaceuticals Inc(TARS) | COM | 87650L103 | $71.8M | 1,397,527 | 3.3% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $64.5M | 10,259,409 | 2.9% |
| Phathom Pharmaceuticals Inc(PHAT) | COM | 71722W107 | $63.4M | 10,109,279 | 2.9% |
| Kalvista Pharmaceuticals Inc(KALV) | COM | 483497103 | $56.4M | 4,887,867 | 2.6% |
| Maze Therapeutics Inc(MAZE) | COM | 578784100 | $45.5M | 4,129,001 | 2.1% |
| MBX Biosciences Inc(MBX) | COM | 55287L101 | $44.2M | 5,985,347 | 2.0% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $36.0M | 678,760 | 1.6% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $35.7M | 499,159 | 1.6% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $35.3M | 997,455 | 1.6% |
| Savara Inc(SVRA) | COM | 805111101 | $31.8M | 11,462,301 | 1.5% |
| Agios Pharmaceuticals Inc(AGIO) | COM | 00847X104 | $31.3M | 1,069,854 | 1.4% |
| Erasca Inc(ERAS) | COM | 29479A108 | $30.9M | 22,575,851 | 1.4% |
| Ultragenyx Pharmaceutical in(RARE) | COM | 90400D108 | $23.9M | 658,715 | 1.1% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $20.8M | 133,333 | 0.9% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $20.4M | 539,405 | 0.9% |
| Alkermes PLC(ALKS) | SHS | G01767105 | $19.8M | 601,129 | 0.9% |
| Palvella Therapeutics Inc NE(PVLA) | COM | 697947109 | $19.3M | 690,012 | 0.9% |
| CG Oncology Inc(CGON) | COM | 156944100 | $18.9M | 770,000 | 0.9% |
| Mereo Biopharma Group PLC(MREO) | SPON ADS | 589492107 | $17.6M | 7,819,863 | 0.8% |
| Merus N V | COM | N5749R100 | $15.7M | 373,100 | 0.7% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $15.5M | 525,000 | 0.7% |
| Hillevax Inc | COM | 43157M102 | $15.4M | 10,617,062 | 0.7% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $15.1M | 1,443,341 | 0.7% |
| ZAI LAB LTD(ZLAB) | ADR | 98887Q104 | $12.6M | 350,000 | 0.6% |
| Immunocore Hldgs PLC(IMCR) | ADS | 45258D105 | $8.9M | 301,170 | 0.4% |
| Oric Pharmaceuticals Inc(ORIC) | COM | 68622P109 | $7.9M | 1,410,193 | 0.4% |
| Acadia Pharmaceuticals Inc(ACAD) | COM | 004225108 | $7.8M | 470,338 | 0.4% |
| Design Therapeutics Inc(DSGN) | COM | 25056L103 | $7.5M | 1,953,547 | 0.3% |
| Rocket Pharmaceuticals Inc(RCKT) | COM | 77313F106 | $7.2M | 1,079,025 | 0.3% |
| Autolus Therapeutics PLC(AUTL) | SPON ADS | 05280R100 | $7.2M | 4,623,324 | 0.3% |
| Oruka Therapeutics Inc(ORKA) | COM | 687604108 | $6.0M | 583,327 | 0.3% |
| Allogene Therapeutics Inc(ALLO) | COM | 019770106 | $5.6M | 3,868,750 | 0.3% |
| Immatics N.v(IMTX) | SHS | N44445109 | $5.6M | 1,247,911 | 0.3% |
| Cogent Biosciences Inc(COGT) | COM | 19240Q201 | $5.6M | 936,576 | 0.3% |
| Adverum Biotechnologies Inc(AVU0) | COM NEW | 00773U207 | $4.7M | 1,069,244 | 0.2% |
| Newamsterdam Pharma Company | *W EXP 99/99/999 | N62509117 | $4.5M | 500,333 | 0.2% |
| Macrogenics Inc(MGNX) | COM | 556099109 | $4.0M | 3,175,665 | 0.2% |
| Lexeo Therapeutics Inc(LXEO) | COM | 52886X107 | $3.3M | 955,515 | 0.2% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $3.2M | 1,148,591 | 0.1% |
| Elevation Oncology Inc | COM | 28623U101 | $1.6M | 5,993,579 | 0.1% |