Q1 2025 Holdings
Filed 2025-05-14 | 117 holdings | $1.8B | 13F-HR/A | View on SEC ↗ · Holdings Table ↗
Amended (2025-05-23) | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Scholar Rock Holding Corp(SRRK) | COM | 80706P103 | $297.4M | 9,250,005 | 16.8% |
| Beigene Ltd(ONC) | SPONSORED ADS | 07725L102 | $135.7M | 498,689 | 7.7% |
| Kymera Therapeutics Inc(KYMR) | COM | 501575104 | $88.7M | 3,240,313 | 5.0% |
| Blueprint Medicines Corp(2L9) | COM | 09627Y109 | $64.3M | 726,167 | 3.6% |
| Crinetics Pharmaceuticals Inc(CRNX) | COM | 22663K107 | $56.6M | 1,688,611 | 3.2% |
| Apellis Pharmaceuticals Inc(APLS) | COM | 03753U106 | $56.4M | 2,578,396 | 3.2% |
| Disc Medicine Inc(IRON) | COM | 254604101 | $53.2M | 1,071,865 | 3.0% |
| Soleno Therapeutics Inc(SLNO) | COM | 834203309 | $52.0M | 727,337 | 2.9% |
| Ascendis Pharma A/S(ASND) | SPONSORED ADR | 04351P101 | $44.8M | 287,366 | 2.5% |
| Merus NV | COM | N5749R100 | $43.9M | 1,043,467 | 2.5% |
| Bicara Therapeutics Inc(BCAX) | COM | 055477103 | $42.6M | 3,267,083 | 2.4% |
| Centessa Pharmaceuticals PLC(CNTA) | SPONSORED ADS | 152309100 | $42.6M | 2,960,029 | 2.4% |
| NewAmsterdam Pharma Company NV(NAMS) | ORDINARY SHARES | N62509109 | $39.1M | 1,912,030 | 2.2% |
| Edgewise Therapeutics Inc(EWTX) | COM | 28036F105 | $37.3M | 1,696,444 | 2.1% |
| Arrowhead Pharmaceuticals Inc(ARWR) | COM | 04280A100 | $34.0M | 2,669,880 | 1.9% |
| Avidity Biosciences Inc(RNA) | COM | 05370A108 | $32.8M | 1,110,610 | 1.8% |
| Wave Life Sciences Ltd(WVE) | SHS | Y95308105 | $29.9M | 3,696,322 | 1.7% |
| Taboola.com Ltd(TBLA) | ORD SHS | M8744T106 | $29.4M | 9,969,495 | 1.7% |
| Dyne Therapeutics Inc(DYN) | COM | 26818M108 | $28.4M | 2,717,987 | 1.6% |
| Solid Biosciences Inc(SLDB) | COM NEW | 83422E204 | $27.4M | 7,415,905 | 1.5% |
| Xenon Pharmaceuticals Inc(XENE) | COM | 98420N105 | $24.6M | 732,761 | 1.4% |
| Apogee Therapeutics Inc(APGE) | COM | 03770N101 | $22.2M | 594,994 | 1.3% |
| Revolution Medicines Inc(RVMD) | COM | 76155X100 | $19.9M | 563,755 | 1.1% |
| Trevi Therapeutics Inc(TRVI) | COM | 89532M101 | $18.0M | 2,863,793 | 1.0% |
| Vera Therapeutics Inc(VERA) | CL A | 92337R101 | $17.9M | 747,216 | 1.0% |
| Lexicon Pharmaceuticals Inc(LXRX)A | COM NEW | 528872302 | $17.9M | 38,918,903 | 1.0% |
| Prothena Corporation PLC(PRTA) | SHS | G72800108 | $15.9M | 1,283,555 | 0.9% |
| Bicycle Therapeutics PLC(BCYC) | SPONSORED ADS | 088786108 | $15.4M | 1,812,752 | 0.9% |
| Stoke Therapeutics Inc(STOK) | COM | 86150R107 | $14.9M | 2,247,347 | 0.8% |
| Rhythm Pharmaceuticals Inc(RYTM) | COM | 76243J105 | $14.7M | 277,533 | 0.8% |
| Summit Therapeutics Inc(SMMT) | COM | 86627T108 | $13.4M | 695,000 | 0.8% |
| Septerna Inc(SEPN) | COM | 81734D104 | $12.8M | 2,202,514 | 0.7% |
| Arcus Biosciences Inc(RCUS) | COM | 03969F109 | $12.7M | 1,612,077 | 0.7% |
| IHS Holding Limited(IHS) | ORD SHS | G4701H109 | $12.3M | 2,357,520 | 0.7% |
| Erasca Inc(ERAS) | COM | 29479A108 | $12.0M | 8,757,249 | 0.7% |
| Denali Therapeutics Inc(DNLI) | COM | 24823R105 | $11.2M | 821,513 | 0.6% |
| Vaxcyte Inc(PCVX) | COM | 92243G108 | $11.2M | 295,543 | 0.6% |
| Amazon.com Inc(AMZN) | COM | 023135106 | $10.7M | 56,500 | 0.6% |
| Microsoft Corp(MSFT) | COM | 594918104 | $10.7M | 28,500 | 0.6% |
| Remitly Global Inc(RELY) | COM | 75960P104 | $10.2M | 490,449 | 0.6% |
| Taysha Gene Therapies Inc(TSHA) | COM SHS | 877619106 | $9.1M | 6,514,737 | 0.5% |
| Cullinan Therapeutics Inc(CGEM) | COM | 230031106 | $9.0M | 1,193,410 | 0.5% |
| CrowdStrike Holdings Inc(CRWD) | CL A | 22788C105 | $8.8M | 25,000 | 0.5% |
| Silence Therapeutics PLC(SLN) | ADS | 82686Q101 | $7.9M | 2,789,833 | 0.4% |
| Alphabet Inc(GOOGL) | CAP STK CL A | 02079K305 | $7.8M | 50,703 | 0.4% |
| Cartesian Therapeutics Inc(RNAC) | COM NEW | 816212302 | $7.4M | 563,272 | 0.4% |
| Adobe Inc(ADBE) | COM | 00724F101 | $7.4M | 19,298 | 0.4% |
| Korro Bio Inc(KRRO) | COM | 500946108 | $7.3M | 418,833 | 0.4% |
| ServiceNow Inc(NOW) | COM | 81762P102 | $7.3M | 9,126 | 0.4% |
| Seer Inc(SEER) | COM CL A | 81578P106 | $6.8M | 4,000,000 | 0.4% |