Q2 2026 Holdings
Filed 2026-08-14 | 85 holdings | $11.5B | 13F-HR | View on SEC ↗ · Holdings Table ↗
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| Issuer | Class | CUSIP | Value ↓ | Shares | % Portfolio |
|---|---|---|---|---|---|
| Ascendis Pharma A/S(ASND) | Common Stock | K08588103 | $2.7B | 10,281,496 | 23.8% |
| Parabilis Medicines Inc(PBLS) | Common Stock | 698955101 | $791.9M | 28,933,371 | 6.9% |
| Rhythm Pharmaceuticals Inc(RYTM) | Common Stock | 76243J105 | $740.2M | 6,666,837 | 6.4% |
| Vaxcyte Inc(PCVX) | Common Stock | 92243G108 | $667.0M | 11,474,599 | 5.8% |
| Sionna Therapeutics Inc(SION) | Common Stock | 829401108 | $435.7M | 9,905,045 | 3.8% |
| Tyra Biosciences Inc(TYRA) | Common Stock | 90240B106 | $389.6M | 12,198,625 | 3.4% |
| Edgewise Therapeutics Inc(EWTX) | Common Stock | 28036F105 | $341.0M | 8,392,730 | 3.0% |
| Newamsterdam Pharma Co NV(NAMS) | Common Stock | N62509109 | $323.7M | 9,550,191 | 2.8% |
| Hemab Therapeutics Holdings(COAG) | Common Stock | 423494103 | $286.8M | 7,808,627 | 2.5% |
| Septerna Inc(SEPN) | Common Stock | 81734D104 | $234.3M | 6,995,858 | 2.0% |
| Bicara Therapeutics Inc(BCAX) | Common Stock | 055477103 | $215.4M | 7,255,993 | 1.9% |
| Mineralys Therapeutics Inc(MLYS) | Common Stock | 603170101 | $207.6M | 7,692,750 | 1.8% |
| GH Research PLC(GHRS) | Common Stock | G3855L106 | $205.3M | 7,636,813 | 1.8% |
| Disc Medicine Inc(IRON) | Common Stock | 254604101 | $179.2M | 2,450,221 | 1.6% |
| Spyglass Pharma Inc(SGP) | Common Stock | 85220G109 | $178.6M | 8,021,117 | 1.6% |
| Artiva Biotherapeutics Inc(ARTV) | Common Stock | 04317A107 | $174.2M | 17,955,642 | 1.5% |
| Janux Therapeutics Inc(JANX) | Common Stock | 47103J105 | $171.9M | 11,189,693 | 1.5% |
| Taysha Gene Therapies Inc(TSHA) | Common Stock | 877619106 | $160.4M | 23,555,648 | 1.4% |
| Biocryst Pharmaceuticals Inc(BCRX) | Common Stock | 09058V103 | $158.3M | 15,827,186 | 1.4% |
| Wave Life Sciences LTD(WVE) | Common Stock | Y95308105 | $156.7M | 26,975,505 | 1.4% |
| Nuvalent Inc(NUVL) | Common Stock | 670703107 | $153.9M | 1,246,456 | 1.3% |
| Abivax SA(ABVX) | ADR | 00370M103 | $150.9M | 1,132,557 | 1.3% |
| Oruka Therapeutics Inc(ORKA) | Common Stock | 687604108 | $148.0M | 1,554,597 | 1.3% |
| Climb BIO Inc(CLYM) | Common Stock | 28658R106 | $147.4M | 11,300,939 | 1.3% |
| Solid Biosciences Inc(SLDB) | Common Stock | 83422E204 | $120.2M | 12,036,126 | 1.0% |
| ZAI LAB LTD(ZLAB) | ADR | 98887Q104 | $109.1M | 5,743,533 | 0.9% |
| ARS Pharmaceuticals Inc(SPRY) | Common Stock | 82835W108 | $87.0M | 10,860,977 | 0.8% |
| Xencor Inc(XNCR) | Common Stock | 98401F105 | $84.9M | 5,274,274 | 0.7% |
| Jade Biosciences Inc(JBIO) | Common Stock | 008064206 | $81.6M | 3,671,083 | 0.7% |
| Intellia Therapeutics Inc(NTLA) | Common Stock | 45826J105 | $76.6M | 4,526,926 | 0.7% |
| LB Pharmaceuticals Inc(LBRX) | Common Stock | 50180M108 | $71.7M | 2,208,604 | 0.6% |
| Definium Therapeutics Inc(DFTX) | Common Stock | 24477V105 | $70.6M | 1,500,000 | 0.6% |
| Aclaris Therapeutics Inc(ACRS) | Common Stock | 00461U105 | $67.3M | 12,723,026 | 0.6% |
| 4D Molecular Therapeutics in(FDMT) | Common Stock | 35104E100 | $67.2M | 5,049,779 | 0.6% |
| Sana Biotechnology Inc(SANA) | Common Stock | 799566104 | $65.4M | 18,750,000 | 0.6% |
| Damora Therapeutics Inc(GLTO) | Common Stock | 36322Q206 | $62.4M | 2,399,702 | 0.5% |
| Monopar Therapeutics Inc(MNPR) | Common Stock | 61023L207 | $61.8M | 667,207 | 0.5% |
| Acumen Pharmaceuticals Inc(ABOS) | Common Stock | 00509G209 | $56.1M | 20,992,669 | 0.5% |
| Geron Corp(GERN) | Common Stock | 374163103 | $54.8M | 42,809,751 | 0.5% |
| Rezolute Inc(RZLT) | Common Stock | 76200L309 | $49.1M | 9,445,039 | 0.4% |
| Evommune Inc(EVMN) | Common Stock | 30054Y107 | $46.4M | 3,494,638 | 0.4% |
| VOR Biopharma Inc(VOR) | Common Stock | 929033207 | $44.2M | 2,402,095 | 0.4% |
| Century Therapeutics Inc(IPSC) | Common Stock | 15673T100 | $43.5M | 17,754,430 | 0.4% |
| Aktis Oncology Inc(AKTS) | Common Stock | 01021M104 | $42.4M | 1,314,405 | 0.4% |
| Bioage Labs Inc(BIOA) | Common Stock | 09077V100 | $41.0M | 1,671,648 | 0.4% |
| C4 Therapeutics Inc(CCCC) | Common Stock | 12529R107 | $37.4M | 8,000,000 | 0.3% |
| Mirum Pharmaceuticals Inc(MIRM) | Common Stock | 604749101 | $37.3M | 318,554 | 0.3% |
| Capricor Therapeutics Inc(CAPR) | Common Stock | 14070B309 | $36.3M | 1,507,844 | 0.3% |
| Pepgen Inc(PEPG) | Common Stock | 713317105 | $36.1M | 20,064,545 | 0.3% |
| Prelude Therapeutics Inc(PRLD) | Common Stock | 74065P101 | $34.5M | 6,475,882 | 0.3% |